Stress Neurobiology Workshop 2012

压力神经生物学研讨会 2012

• 批准号: 8400120
• 负责人: TERESA M REYES
• 金额: $ 2.5万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-07-01 至 2013-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8400120
• 关键词: Address; Adolescent; Adverse effects; Behavior; Biology; Brain; Caring; Child; Clinical; Collaborations; Commit; Communities; Data; Development; Discipline; Disease; Drug Addiction; Drug abuse; Drug usage; Education; Educational workshop; Environment; Epigenetic Process; Exposure to; Family; Fees; Fostering; Funding; Future; Gene Expression Regulation; Goals; Grant; Hour; Institutes; International; Journals; Knowledge; Mental Depression; Mental Health; Minority; Molecular; National Institute of Drug Abuse; Neurobiology; Pediatric Hospitals; Pennsylvania; Pharmacologic Substance; Philadelphia; Physiology; Post-Traumatic Stress Disorders; Postdoctoral Fellow; Process; Productivity; Publications; Publishing; Recruitment Activity; Regulation; Relapse; Research; Research Personnel; Resources; Risk Factors; Role; Scientist; Secure; Sex Characteristics; Societies; Stress; Suggestion; Time; Training; Travel; Underrepresented Minority; Universities; Vendor; Woman; Work; addiction; base; biological adaptation to stress; career development; clinically relevant; drug relapse; graduate student; interest; meetings; member; minority trainee; neural circuit; neurobiological mechanism; next generation; novel; physical conditioning; posters; pre-clinical; programs; sex; social; stress related disorder; symposium

DESCRIPTION (provided by applicant): While many factors may contribute to initial and continued drug use, exposure to stress at any point in the addiction cycle appears to worsen this disease. Therefore, it is critical to advance our knowledge about the neurobiological underpinnings of stress. The role of stress in drug addiction/relapse has not been addressed in previous Stress Neurobiology Workshops, and is therefore the focus of the current workshop. A Neurobiology of Stress Workshop will be organized for June 12-15th, 2012 at the University of Pennsylvania, Philadelphia, PA. This rigorous scientific meeting will bring together preclinical and clinical researchers who study stress-brain interactions. This Workshop addresses an important need to strengthen the community of stress researchers in a manner that will maximize the productivity and clinical benefit of future stress research. Thus, the Workshop will provide a unique opportunity for researchers to participate in face-to-face examination of recent research advances, to share perspectives, identify relevant issues, debate controversies and exchange diverse expertise. Five sessions are planned in which invited speakers will present new research work, novel ideas, and examination of clinically relevant issues. These sessions are: (1) The role of stress in drug addiction and relapse, (2) Epigenetics and Stress, (3) Neurobiological mechanisms underlying stress-related disorders, (4) Molecular Mechanisms and Neural Circuits in Stress Regulation, and (5) Stress effects in vulnerable development time periods. A keynote presentation will be given by Dr. George Koob. In addition to the discussion time within each session, the Workshop features extensive time for interaction among all attendees at the opening data blitz reception, shared daily lunch period, Poster Session, and a social hour. A priority of the Workshop is to foster the professional development of new investigators and women by including them at all levels of meeting organization and Program participation. Further the Workshop will nurture career development of graduate students and postdoctoral researchers by giving them ample opportunity to participate in the Workshop via the data blitz session, Poster Session, discussion sessions, and issue-related luncheon roundtables. Travel Grants will be made available to select trainees through a merit based application process, with a detailed plan in place to recruit applications from interested minority candidates. This revised application of a highly scored initial application has incorporated all of the reviewers suggestions. PUBLIC HEALTH RELEVANCE: The adverse effects of stress on mental and physical health have come to the fore as one of the most pressing biomedical problems in our society. The proposed Neurobiology of Stress Workshop to be held June 12-15th at the University of Pennsylvania will bring together basic, preclinical and clinical researchers and affiliated trainee in order to significantly enhance the productivity and clinical benefit of future stress research.

描述（由申请人提供）：虽然许多因素可能导致最初和持续吸毒，但在成瘾周期的任何时候暴露于压力似乎都会使这种疾病恶化。因此，增进我们对压力的神经生物学基础的了解至关重要。压力在毒瘾/复发中的作用在之前的压力神经生物学研讨会中尚未得到解决，因此是本次研讨会的重点。压力神经生物学研讨会将于 2012 年 6 月 12 日至 15 日在宾夕法尼亚州费城宾夕法尼亚大学举办。这次严格的科学会议将汇集研究压力与大脑相互作用的临床前和临床研究人员。本次研讨会解决了加强压力研究人员社区的重要需求，以最大限度地提高未来压力研究的生产力和临床效益。因此，研讨会将为研究人员提供一个独特的机会，让他们参与面对面审查最新研究进展、分享观点、确定相关问题、辩论争议和交流不同的专业知识。计划举行五场会议，受邀演讲者将介绍新的研究工作、新颖的想法以及对临床相关问题的审查。这些会议包括：(1) 压力在毒瘾和复发中的作用，(2) 表观遗传学和压力，(3) 压力相关疾病的神经生物学机制，(4) 压力调节中的分子机制和神经回路，以及 (5) 脆弱发育时期的压力影响。乔治·库布博士将发表主题演讲。 除了每场会议的讨论时间外，研讨会还为所有与会者提供了大量的互动时间，包括开幕数据闪电招待会、每日共享午餐时间、海报会议和社交时间。研讨会的一个优先事项是通过让新研究者和女性参与各级会议组织和计划参与来促进新研究者和女性的专业发展。此外，研讨会还将通过数据闪电会议、海报会议、讨论会和与问题相关的午餐圆桌会议为研究生和博士后研究人员提供充足的机会参与研讨会，从而促进研究生和博士后研究人员的职业发展。将通过基于绩效的申请流程向选定的学员提供旅行补助金，并制定详细计划以从感兴趣的少数群体中招募申请 候选人。这个高分初始申请的修订申请已纳入所有 审稿人的建议。 公共卫生相关性：压力对身心健康的不利影响已成为我们社会最紧迫的生物医学问题之一。拟议的压力神经生物学研讨会将于 6 月 12 日至 15 日在宾夕法尼亚大学举行，将汇集基础、临床前和临床研究人员以及附属实习生，以显着提高未来压力研究的生产力和临床效益。