Stress Neurobiology Workshop 2012

描述（由申请人提供）：虽然许多因素可能有助于初始和持续使用药物，但在成瘾周期的任何时候暴露于压力似乎都会使这种疾病恶化。因此，提高我们对压力的神经生物学基础的认识至关重要。压力在药物成瘾/复吸中的作用在以前的压力神经生物学研讨会中没有得到解决，因此是当前研讨会的重点。压力研讨会的神经生物学将于2012年6月12日至15日在宾夕法尼亚大学费城举行。这个严格的科学会议将汇集临床前和临床研究人员谁研究压力大脑的相互作用。本次研讨会解决了一个重要的需要，以加强社区的压力研究人员的方式，将最大限度地提高生产力和临床效益的未来压力研究。因此，讲习班将为研究人员提供一个独特的机会，使他们能够参加对最近研究进展的面对面审查，分享观点，确定相关问题，辩论争议和交流各种专门知识。计划举办五次会议，邀请演讲者将介绍新的研究工作，新颖的想法和临床相关问题的检查。这些会议是：（1）压力在药物成瘾和复发中的作用，（2）表观遗传学和压力，（3）压力相关疾病的神经生物学机制，（4）压力调节的分子机制和神经回路，（5）脆弱发育时期的压力效应。乔治库布博士将作主旨发言。 除了每个会议的讨论时间外，研讨会还在开幕式数据闪电战接待会、每日共享午餐时间、海报会议和社交时间为所有与会者提供了大量的互动时间。讲习班的一个优先事项是促进新调查员和妇女的专业发展，让她们参加各级会议组织和方案参与。此外，研讨会将通过数据闪电会议，海报会议，讨论会和与问题相关的午餐圆桌会议，为研究生和博士后研究人员提供充分的机会参与研讨会，以促进他们的职业发展。将通过基于成绩的申请程序向选定的学员提供旅行赠款，并制定详细计划，以招募感兴趣的少数族裔申请人 候选人这一高评分的初始申请的修订申请纳入了所有 评论者的建议。 公共卫生相关性：压力对身心健康的不利影响已经成为我们社会中最紧迫的生物医学问题之一。拟于6月12日至15日在宾夕法尼亚大学举行的应激神经生物学研讨会将汇集基础，临床前和临床研究人员和附属实习生，以显着提高未来应激研究的生产力和临床效益。

DESCRIPTION (provided by applicant): While many factors may contribute to initial and continued drug use, exposure to stress at any point in the addiction cycle appears to worsen this disease. Therefore, it is critical to advance our knowledge about the neurobiological underpinnings of stress. The role of stress in drug addiction/relapse has not been addressed in previous Stress Neurobiology Workshops, and is therefore the focus of the current workshop. A Neurobiology of Stress Workshop will be organized for June 12-15th, 2012 at the University of Pennsylvania, Philadelphia, PA. This rigorous scientific meeting will bring together preclinical and clinical researchers who study stress-brain interactions. This Workshop addresses an important need to strengthen the community of stress researchers in a manner that will maximize the productivity and clinical benefit of future stress research. Thus, the Workshop will provide a unique opportunity for researchers to participate in face-to-face examination of recent research advances, to share perspectives, identify relevant issues, debate controversies and exchange diverse expertise. Five sessions are planned in which invited speakers will present new research work, novel ideas, and examination of clinically relevant issues. These sessions are: (1) The role of stress in drug addiction and relapse, (2) Epigenetics and Stress, (3) Neurobiological mechanisms underlying stress-related disorders, (4) Molecular Mechanisms and Neural Circuits in Stress Regulation, and (5) Stress effects in vulnerable development time periods. A keynote presentation will be given by Dr. George Koob. In addition to the discussion time within each session, the Workshop features extensive time for interaction among all attendees at the opening data blitz reception, shared daily lunch period, Poster Session, and a social hour. A priority of the Workshop is to foster the professional development of new investigators and women by including them at all levels of meeting organization and Program participation. Further the Workshop will nurture career development of graduate students and postdoctoral researchers by giving them ample opportunity to participate in the Workshop via the data blitz session, Poster Session, discussion sessions, and issue-related luncheon roundtables. Travel Grants will be made available to select trainees through a merit based application process, with a detailed plan in place to recruit applications from interested minority candidates. This revised application of a highly scored initial application has incorporated all of the reviewers suggestions. PUBLIC HEALTH RELEVANCE: The adverse effects of stress on mental and physical health have come to the fore as one of the most pressing biomedical problems in our society. The proposed Neurobiology of Stress Workshop to be held June 12-15th at the University of Pennsylvania will bring together basic, preclinical and clinical researchers and affiliated trainee in order to significantly enhance the productivity and clinical benefit of future stress research.