VACCINES FOR CHLAMYDIA TRACHOMATIS INFECTIONS

沙眼衣原体感染疫苗

• 批准号: 8357310
• 负责人: LUIS M DE LA MAZA
• 金额: $ 2.52万
• 依托单位: UNIVERSITY OF CALIFORNIA AT DAVIS
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-05-01 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8357310
• 关键词: California; Chlamydia trachomatis; Funding; Grant; Human; Immune response; Infection; Macaca mulatta; Modeling; National Center for Research Resources; Primates; Principal Investigator; Proteins; Research; Research Infrastructure; Resources; Source; United States National Institutes of Health; Vaccines; cost; nonhuman primate; preclinical study

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The objective of this project is to demonstrate that Chlamydia trachomatis proteins stimulate vigorous immune responses in immunized rhesus macaques. This is a pre-clinical study in a nonhuman primate model with direct translational relevance to studies in humans.

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 本项目的目的是证明沙眼衣原体蛋白刺激免疫恒河猴的强烈免疫反应。 这是一项在非人灵长类动物模型中进行的临床前研究，与人类研究有直接的翻译相关性。