STRUCTURAL BIOLOGY OF RNA-MEDIATED PROCESSES AND EPIGENETIC REGULATION

RNA介导过程的结构生物学和表观遗传调控

• 批准号: 8361614
• 负责人: DINSHAW J PATEL
• 金额: $ 4.21万
• 依托单位: CORNELL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-01 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8361614
• 关键词: Alternative Splicing; Bypass; Complex; Epigenetic Process; Family; Funding; Gene Expression Regulation; Grant; Histones; Mediating; National Center for Research Resources; Pattern recognition receptor; Polymerase; Principal Investigator; Proteins; RNA; Reader; Regulation; Research; Research Infrastructure; Resources; Source; United States National Institutes of Health; cost; structural biology

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. (a) Structural biology of riboswitches and gene regulation (b) Structural biology protein-RNA complexes mediating alternate splicing (c) Structural biology of damage bypass by Y family polymerases (d) Structural biology of pattern recognition receptors (e) Structural biology of readers and erasers of histone marks

这个子项目是利用资源的许多研究子项目之一。 由NIH/NCRR资助的中心拨款提供。对子项目的主要支持 子项目的首席调查员可能是由其他来源提供的， 包括美国国立卫生研究院的其他来源。为子项目列出的总成本可能 表示该子项目使用的中心基础设施的估计数量， 不是由NCRR赠款提供给次级项目或次级项目工作人员的直接资金。 (A)核糖开关的结构生物学和基因调控 (B)介导交替剪接的结构生物学蛋白质-RNA复合体 (C)Y家族聚合酶损伤旁路的结构生物学 (D)模式识别受体的结构生物学 (E)组蛋白标记读取器和擦除器的结构生物学