DATA MANAGEMENT AND STATISTICS CORE

核心C：数据管理和统计核心 加州大学欧文分校（UCI）阿尔茨海默病研究中心（ADRC）的数据管理和统计核心（DMSC）的总体目标是在科学项目的所有阶段为所有ADRC研究人员提供后勤和智力支持。因此，DMSC教职员工的使命是密切参与ADRC成员进行的研究的概念，设计，实施，分析和报告。强有力的统计设计、干净有序的数据以及高效的数据分析是实现UCI ADRC提出的科学目标的关键组成部分。考虑到这一点，DMSC强调与ADRC调查人员定期沟通，并积极参与ADRC赞助的项目。虽然DMSC教师的大部分努力都致力于为ADRC调查人员提供合作和服务，但DMSC还将强调和鼓励DMSC成员之间的独立研究计划的发展。这些研究项目将包括开发和验证新的数据收集机制，开发新的统计方法来处理缺失数据，以及开发生存分析的统计方法。这些专门针对DMSC的研究工作不仅会增加DMSC对整个科学界的智力贡献，而且肯定会改进通过当地ADRC获得的复杂数据的收集、输入和分析方法。 项目

CORE C: DATA MANAGEMENT and STATISTICS CORE The overarching goal of the Data Management and Statistics Core (DMSC) within the University of California-Irvine (UCI) Alzheimer's Disease Research Center (ADRC) is to provide logistical and intellectual support to all ADRC investigators at all phases of scientific projects. As such, the mission of the DMSC faculty and staff is to be intimately involved in the conception, design, implementation, analysis, and reporting of research conducted by members of the ADRC. Strong statistical design, clean and organized data, and efficient data analyses are crucial components to achieving the scientific goals set forth by the UCI ADRC. With this in mind the DMSC emphasizes regular communication with ADRC investigators and proactive involvement in ADRC-sponsored projects. While a large portion of effort from DMSC faculty has been devoted to providing collaboration and service to ADRC investigators, the DMSC will also emphasize and encourage the development of independent research programs among members of the DMSC. These research projects will include the development and validation of novel data collection mechanisms, the development of new statistical methodology for addressing missing data, and the development of statistical methods for survival analysis. These DMSC-specific research endeavors will not only increase the intellectual contribution of the DMSC to the scientific community at large, but will most certainly lead to improved methods for collecting, entering, and analyzing complex data obtained through local ADRC projects.