ESR MICROSCOPE MKII HIGH VOLTAGE PREREGULATOR

ESR 显微镜 MKII 高压预调节器

• 批准号: 8364083
• 负责人: CURT R DUNNAM
• 金额: $ 1.5万
• 依托单位: CORNELL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-01 至 2012-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8364083
• 关键词: Automobile Driving; Biological; Devices; Electric Capacitance; Funding; Generations; Goals; Grant; Image; Microscope; Modification; National Center for Research Resources; Output; Physiologic pulse; Principal Investigator; Research; Research Infrastructure; Resolution; Resources; Signal Transduction; Source; System; Technology; United States National Institutes of Health; Width; cost; voltage

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. At its present level of resolution, ~0.7x0.75x0.75¿m, the ACERT Ku-band pulse ESR microscope utilizes peak gradient coil drive voltages of up to 425 volts. For observation of biological ESRM signals, we desire a significantly shorter gradient pulse interval, implying higher voltages and smaller values of driver network energy storage capacitance. Our goals are generation of peak coil drive voltages up to 600 volts, minimum, and pulse widths of 800ns or less at peak gradients approaching 100 T/m. The strategy for accomplishing significantly reduced pulse widths is to upgrade the gradient driver subsystem by installation of 800 volt MOSFET output devices in place of the prior 600 volt devices, and to replace the existing preregulator system that is employed to precharge the driver channel high-voltage capacitors with a substantially upgraded version. Modifications of the gradient driver subsystem to achieve higher output voltage capability have already been made. However, the preregulator driving it is capable of only 450 volts, although ca 11 amperes peak current output. We will replace the preregulator within a few weeks with a MKII version providing two channels of at least 800 volt, 10 amperes capability. With this combined gradient driver system, we anticipate utilizing spin probes with shorter T2, e.g. nitroxides, that are appropriate for biological imaging.

该副本是利用资源的众多研究子项目之一 由NIH/NCRR资助的中心赠款提供。对该子弹的主要支持 而且，副投影的主要研究员可能是其他来源提供的 包括其他NIH来源。列出的总费用可能 代表subproject使用的中心基础架构的估计量， NCRR赠款不直接向子弹或副本人员提供的直接资金。 在目前的分辨率水平上，〜0.7x0.75x0.75¿m，Acert Ku波段脉冲ESR显微镜使用峰值梯度线圈驱动电压高达425伏。为了观察生物ESRM信号，我们希望明显较短的梯度脉冲间隔，这意味着较高的电压和较小的驾驶员网络存储能力值。我们的目标是在接近100 t/m的峰值梯度下产生高达600伏的峰值线圈驱动电压，最小和脉冲宽度为800n或更少。实现显着降低脉冲宽度的策略是通过安装800伏MOSFET输出设备来升级梯度驱动程序子系统，以代替先前的600伏设备，并用来替换现有的预启动器系统，以替换现有的预先调节器系统，以便将驾驶员通道高压助力器与实质上升级的版本相结合。已经对梯度驱动程序子系统的修改已经进行了更高的输出电压能力。然而，驱动前调节器的能力仅能450伏，尽管CA 11安培峰值电流输出。我们将在几周内用MKII版本在几周内替换预算力，提供两个频道，其中两个频道至少为800伏，10安培功能。使用此组合的梯度驱动程序系统，我们预计使用较短的T2来利用自旋问题，例如氮氧化物，适合生物成像。