ESR MICROSCOPE MKII HIGH VOLTAGE PREREGULATOR

ESR 显微镜 MKII 高压预调节器

• 批准号: 8364083
• 负责人: CURT R DUNNAM
• 金额: $ 1.5万
• 依托单位: CORNELL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-01 至 2012-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8364083
• 关键词: Automobile Driving; Biological; Devices; Electric Capacitance; Funding; Generations; Goals; Grant; Image; Microscope; Modification; National Center for Research Resources; Output; Physiologic pulse; Principal Investigator; Research; Research Infrastructure; Resolution; Resources; Signal Transduction; Source; System; Technology; United States National Institutes of Health; Width; cost; voltage

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. At its present level of resolution, ~0.7x0.75x0.75¿m, the ACERT Ku-band pulse ESR microscope utilizes peak gradient coil drive voltages of up to 425 volts. For observation of biological ESRM signals, we desire a significantly shorter gradient pulse interval, implying higher voltages and smaller values of driver network energy storage capacitance. Our goals are generation of peak coil drive voltages up to 600 volts, minimum, and pulse widths of 800ns or less at peak gradients approaching 100 T/m. The strategy for accomplishing significantly reduced pulse widths is to upgrade the gradient driver subsystem by installation of 800 volt MOSFET output devices in place of the prior 600 volt devices, and to replace the existing preregulator system that is employed to precharge the driver channel high-voltage capacitors with a substantially upgraded version. Modifications of the gradient driver subsystem to achieve higher output voltage capability have already been made. However, the preregulator driving it is capable of only 450 volts, although ca 11 amperes peak current output. We will replace the preregulator within a few weeks with a MKII version providing two channels of at least 800 volt, 10 amperes capability. With this combined gradient driver system, we anticipate utilizing spin probes with shorter T2, e.g. nitroxides, that are appropriate for biological imaging.

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其他NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， NCRR赠款不直接向子项目或子项目工作人员提供资金。 在其目前的分辨率水平，~0.7x0.75x0.75 μ m，ACERT Ku波段脉冲ESR显微镜利用高达425伏的峰值梯度线圈驱动电压。对于生物ESRM信号的观察，我们期望显著更短的梯度脉冲间隔，这意味着更高的电压和更小的驱动器网络能量存储电容值。我们的目标是在峰值梯度接近100 T/m时产生最低600 V的峰值线圈驱动电压和800 ns或更小的脉冲宽度。实现显著减小的脉冲宽度的策略是通过安装800伏MOSFET输出器件来代替先前的600伏器件来升级梯度驱动器子系统，并且用实质上升级的版本来替换用于对驱动器通道高压电容器进行预充电的现有预调节器系统。已经对梯度驱动器子系统进行了修改以实现更高的输出电压能力。然而，驱动它的前置稳压器只能提供450伏的电压，尽管大约11安培的峰值电流输出。我们将在几周内用MKII版本取代预调节器，该版本提供至少800伏，10安培能力的两个通道。通过这种组合的梯度驱动系统，我们预期利用具有较短T2的自旋探针，例如氮氧化物，其适合于生物成像。