Aspergillus Genome Database

这个项目的目标是开发一个数据库，基于用于 曲霉的酵母菌和念珠菌基因组数据库，其中将有 从与特定基因相关的文献中精选的数据。在策划文学作品时，我们将 记录基因名称和别名、基因本体论注释以及突变表型 AS为探索基因组及其注释提供了工具和接口。此外，我们还将 进一步开发和提炼一个健壮的、最先进的基因组注释管道，并使用它来 对每个曲霉进行初级基因组注释。这条管道将利用 曲霉之间的比较基因组数据，并将定期重新运行，在以下情况下 新数据浮出水面(例如额外的基因组)，或者当改进的算法 被合并到管道中。因此，我们将向曲霉研究社区提供高 以质量文献为基础的精选，再加上每个文档可能的最佳主要注释 基因组。通过这种方式，就像在其他生物体研究社区中所做的那样，我们将 通过使研究人员能够轻松访问相关的 注释信息。这一点特别重要，因为曲霉既包含 条件致病菌，烟曲霉菌，以及模式遗传有机体，根瘤弧菌，和 对这些生物体的研究将对人类健康产生积极影响。

The goal of this project is to develop a database, based on the software and schema used for the Saccharomyces and Candida Genome Databases, for the Aspergilli, wherein there will be data curated from the literature connected to specific genes. In curating the literature, we will record gene names and aliases, Gene Ontology annotations, and mutant phenotypes, as well as provide tools and interfaces for exploring the genome and its annotations. In addition, we will further develop and refine a robust, state-of-the-art genome annotation pipeline, and use this to perform primary genome annotation on each of the Aspergilli. This pipeline will take advantage of comparative genomic data between the Aspergilli, and will be re-run periodically, either when new data come to light (such as additional genomes), or when improved algorithms are incorporated into the pipeline. Thus, we will provide to the Aspergillus research community high quality literature based curation, coupled with the best possible primary annotation of each of the genomes. In this way, as has been done in other organism research communities, we will help to accelerate research into the Aspergilli, by enabling researchers to easily access relevant annotation information. This is particularly important, as the Aspergilli contain both the opportunistic pathogen, A. fumigaus, as well as the model genetic organism, A. nidulans, and enabling research into these organism will have a positive impact on human health.