Aspergillus Genome Database
Aspergillus Genome Database
批准号:
8197088
负责人:
Gavin J Sherlock
金额:
$64.18万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2008
资助国家:
美国
项目状态:
已结题
起止时间:
2008-12-05 至 2013-11-30
关键词:
AdoptedAlgorithmsAmino Acid SequenceAnimalsAntifungal AgentsArchivesAspergillusAspergillus fumigatusBinding SitesBiological ProcessCandidaCandida albicansChimeric ProteinsCodeCollaborationsCommunicationCommunitiesComparative Genomic AnalysisComparative StudyComplementComputer softwareConsensusCoupledDataData SetDatabasesDiseaseGenesGenetic ModelsGenomeGenomicsGoalsHealthHumanImageryIndiumInfectionInstitutionInternetKnowledgeLinkLiteratureLocationMethodsModelingMoldsMolecularMorbidity - disease rateMutationNamesNucleic Acid Regulatory SequencesNucleic AcidsOntologyOrganismOrthologous GeneOther GeneticsPeptide Sequence DeterminationPharmacotherapyPhenotypePolicy ResearchProtein FamilyProteinsPublishingResearchResearch PersonnelResourcesRestriction MappingRetrievalRunningSaccharomycesScientistServicesSyntenyTechnologyTimeTranscription Initiation SiteTranslatingUntranslated RNAVirulencebasecomparative genomicsdatabase structurefight againstfungusgenetic elementgenome databasegenome sequencingimprovedmortalitymutantpathogenrepositorytooltranscription factorweb-accessible
中文摘要
本项目的目标是开发一个基于软件和模式的数据库,用于
英文摘要
The goal of this project is to develop a database, based on the software and schema used for
the Saccharomyces and Candida Genome Databases, for the Aspergilli, wherein there will be
data curated from the literature connected to specific genes. In curating the literature, we will
record gene names and aliases, Gene Ontology annotations, and mutant phenotypes, as well
as provide tools and interfaces for exploring the genome and its annotations. In addition, we will
further develop and refine a robust, state-of-the-art genome annotation pipeline, and use this to
perform primary genome annotation on each of the Aspergilli. This pipeline will take advantage
of comparative genomic data between the Aspergilli, and will be re-run periodically, either when
new data come to light (such as additional genomes), or when improved algorithms are
incorporated into the pipeline. Thus, we will provide to the Aspergillus research community high
quality literature based curation, coupled with the best possible primary annotation of each of
the genomes. In this way, as has been done in other organism research communities, we will
help to accelerate research into the Aspergilli, by enabling researchers to easily access relevant
annotation information. This is particularly important, as the Aspergilli contain both the
opportunistic pathogen, A. fumigaus, as well as the model genetic organism, A. nidulans, and
enabling research into these organism will have a positive impact on human health.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Fitness Effects of Beneficial Mutations
-
批准号:9913557
-
项目类别:
-
资助金额:$42.81万
-
财政年份:2019
-
负责人:Gavin J Sherlock
-
依托单位:
Fitness Effects of Beneficial Mutations
-
批准号:10612770
-
项目类别:
-
资助金额:$42.98万
-
财政年份:2019
-
负责人:Gavin J Sherlock
-
依托单位:
Fitness Effects of Beneficial Mutations
-
批准号:10391436
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项目类别:
-
资助金额:$42.92万
-
财政年份:2019
-
负责人:Gavin J Sherlock
-
依托单位:
Evolution of drug resistance in Candida glabrata
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批准号:10531319
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项目类别:
-
资助金额:$7.2万
-
财政年份:2018
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负责人:Gavin J Sherlock
-
依托单位:
Adaptation of Candida glabrata to host-associated niches
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批准号:10270449
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项目类别:
-
资助金额:$4.46万
-
财政年份:2018
-
负责人:Gavin J Sherlock
-
依托单位:
Evolution of drug resistance in Candida glabrata
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批准号:10308481
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项目类别:
-
资助金额:$67.49万
-
财政年份:2018
-
负责人:Gavin J Sherlock
-
依托单位:
Evolution of drug resistance in Candida glabrata
-
批准号:10062810
-
项目类别:
-
资助金额:$67.72万
-
财政年份:2018
-
负责人:Gavin J Sherlock
-
依托单位:
PPiSeq: High-Throughput Protein-Protein Interaction Sequencing
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批准号:10653194
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项目类别:
-
资助金额:$41.16万
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财政年份:2015
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负责人:Gavin J Sherlock
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依托单位:
Systematic Molecular Analysis of Antagonistic Pleiotropy
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批准号:8672196
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项目类别:
-
资助金额:$42.45万
-
财政年份:2014
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负责人:Gavin J Sherlock
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依托单位:
Systematic Molecular Analysis of Antagonistic Pleiotropy
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批准号:9243270
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项目类别:
-
资助金额:$38.93万
-
财政年份:2014
-
负责人:Gavin J Sherlock
-
依托单位:
Systematic Molecular Analysis of Antagonistic Pleiotropy
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批准号:9027856
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项目类别:
-
资助金额:$42.06万
-
财政年份:2014
-
负责人:Gavin J Sherlock
-
依托单位:
A publicly-accessible Cryptococcus genome database: annotation of the Cryptococcu
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批准号:8491604
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项目类别:
-
资助金额:$9.09万
-
财政年份:2013
-
负责人:Gavin J Sherlock
-
依托单位:
A publicly-accessible Cryptococcus genome database: annotation of the Cryptococcu
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批准号:8601428
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项目类别:
-
资助金额:$7.79万
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财政年份:2013
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负责人:Gavin J Sherlock
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依托单位:
Analysis of the C.albicansTranscriptome
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批准号:8092581
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项目类别:
-
资助金额:$44.64万
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财政年份:2009
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负责人:Gavin J Sherlock
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依托单位:
Analysis of the C.albicansTranscriptome
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批准号:7737493
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项目类别:
-
资助金额:$48.26万
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财政年份:2009
-
负责人:Gavin J Sherlock
-
依托单位:
Analysis of the C.albicansTranscriptome
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批准号:7876688
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项目类别:
-
资助金额:$45.01万
-
财政年份:2009
-
负责人:Gavin J Sherlock
-
依托单位:
Aspergillus Genome Database
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批准号:8384872
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项目类别:
-
资助金额:$59.24万
-
财政年份:2008
-
负责人:Gavin J Sherlock
-
依托单位:
Aspergillus Genome Database
-
批准号:7991828
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项目类别:
-
资助金额:$70.94万
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财政年份:2008
-
负责人:Gavin J Sherlock
-
依托单位:
Aspergillus Genome Database
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批准号:8893190
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项目类别:
-
资助金额:$76.41万
-
财政年份:2008
-
负责人:Gavin J Sherlock
-
依托单位:
Aspergillus Genome Database
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批准号:7581113
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项目类别:
-
资助金额:$77.62万
-
财政年份:2008
-
负责人:Gavin J Sherlock
-
依托单位:
海外基金