Vanderbilt Site for Network of Excellence in Neuroscience Clinical Trials

范德比尔特神经科学临床试验卓越网络网站

• 批准号: 8339418
• 负责人: BETH A MALOW
• 金额: $ 31.2万
• 依托单位: VANDERBILT UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-30 至 2018-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8339418
• 关键词: Adult; Child; Clinical Research; Clinical Trials; Clinical Trials Network; Collaborations; Commit; Data Quality; Disease; Educational Background; Enrollment; Environment; Faculty; Fostering; Foundations; Funding; Goals; Industry; Institutes; Institutional Review Boards; Internal Medicine; Leadership; Mentorship; Modeling; Multicenter Trials; National Institute of Neurological Disorders and Stroke; Neurologic; Neurosciences; Participant; Pediatric Neurology; Positioning Attribute; Principal Investigator; Psychiatry; Research; Research Infrastructure; Research Personnel; Resources; Site; Students; Training; Translating; Translational Research; United States National Institutes of Health; Universities; clinical practice; clinical research site; data integrity; experience; innovation; meetings; multidisciplinary; nervous system disorder; neurosurgery; response

DESCRIPTION (provided by applicant): Vanderbilt University is ideally positioned to be a clinical site in the Network of Excellence in Neuroscience Clinical Trials (NEXT). The Principal Investigator and her co-investigators have participated in a multitude of diverse disease-oriented networks and multicenter trials, and have a strong track record of developing and participating in innovative trials with NIH (including NINDS), industry, and foundation support. The Vanderbilt NINDS Clinical Trials team will leverage the many strengths of the collegial, multidisciplinary environment for clinical and translational research on our campus, including the Vanderbilt Institute for Clinical and Translational Research, 38 funded Cores and Centers, and rich collaborations among the departments of Neurology, Pediatrics, Neurosurgery, Psychiatry, and Internal Medicine. Our overarching goal is to establish a Vanderbilt neuroscience clinical trials network site that is uniquely positioned to translate neuroscience advances into clinical practice through the conduct of exploratory clinical trials. Our Specific Aims are: (1) To fully engage our collaborative leadership team in developing a transformative neuroscience network site that is agile and responsive to the needs of the overall NINDS Clinical Trials Network; (2) To leverage the abundant institutional resources of the Vanderbilt research enterprise-this will provide the NINDS Clinical Trials Network with deliverables including high enrollment and retention of study participants, with an emphasis on quality data and data integrity; and (3) To establish a cadre of new investigators focused on the developing and implementing neurological clinical trials. We are uniquely poised to provide mentorship and collaboration at all levels of education, including students, residents, fellows, junior faculty, and research staff. Vanderbilt is also committed to utilization of a central Institutional Review Board (IRB) model to aid in the efficiency of IRB reviews and to sharing of successful clinical trial practices with the other NINDS Clinical Trials Network sites.

描述（由申请人提供）：范德比尔特大学（Vanderbilt University）是神经科学临床试验卓越网络（下一个）的临床场所（下一个）。首席研究员及其共同研究人员参加了许多不同的面向疾病的网络和多中心试验，并在与NIH（包括Ninds），行业和基金会支持的创新试验中具有良好的良好记录。 Vanderbilt Ninds临床试验团队将利用校园的临床和转化研究，包括范德比尔特临床和转化研究所，38个资助的核心和中心，以及神经学部门，神经学，培养基，神经疗法，精神疗法，精神疗法和内部，包括38个资助的核心和中心。 我们的总体目标是建立一个范德比尔特神经科学临床试验网站，该网站是通过进行探索性临床试验将神经科学进步转化为临床实践的独特位置。我们的具体目标是：（1）充分吸引我们的协作领导团队，以开发一个变革性的神经科学网站，该网站敏捷且响应了整个NINDS临床试验网络的需求； （2）为了利用范德比尔特研究企业的丰富机构资源 - 这将为Ninds临床试验网络提供可交付成果，包括高入学和保留研究参与者，重点是质量数据和数据完整性； （3）建立一批新的研究人员，专注于发展和实施神经系统临床试验。我们有独特的准备在各个级别的教育中提供指导和协作，包括学生，居民，研究员，初级教师和研究人员。 范德比尔特还致力于利用中央机构审查委员会（IRB）模型，以协助IRB审查的效率，并与其他NINDS临床试验网站共享成功的临床试验实践。