课题基金 / 基金详情

Nanoparticle-Enhanced Magneto-Acoustic Tomography

纳米颗粒增强磁声断层扫描

批准号：

8564406

负责人：

Gary Mikaelian

金额：

$17.08万

依托单位：

PHYSICAL OPTICS CORPORATION

依托单位国家：

美国

项目类别：

财政年份：

2012

资助国家：

美国

项目状态：

已结题

起止时间：

2012-09-28 至 2013-06-27

来源：

https://reporter.nih.gov/project-details/8564406

关键词：

Acoustics Address Algorithms Amines Animal Model Bathing Binding Businesses Computer software Computers Contracts Dendrimers Detection Development Funding Generations Glutamate Carboxypeptidase II Goals Healthcare Market IACUC Image In Vitro Magnetism Market Research Measurement Phase Polyethylene Glycols Predisposition Process Protocols documentation Relaxation Reporting Sampling Shapes Site Source System Technology Time Ultrasonic Transducer Universities acoustic imaging base cancer site carboxylate commercialization data acquisition design file format functional group image reconstruction in vivo iron oxide laptop man nanocarrier nanoparticle operation phantom model prototype research study self assembly sensor technical report tomography tumor

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中文摘要

翻译

该项目的总体目标是解决NCI的需求，通过开发和首次，

英文摘要

The overall goal of this project is to address the NCI need by developing and, for the first time, demonstrating relaxation-time-selective magneto-acoustic detection of functionalized iron oxide nanoparticles. Functionalized magnetic nanoparticles will be developed for specific aggregation at the tumor site. A nanoparticle-enhanced magneto-acoustic tomography (NEMAT) detection system will be designed and developed including the magnetoacoustic, and magnetic susceptibility measurement systems. A Phase I NEMAT prototype will be fabricated and assembled, and its operation demonstrated on phantom models. Final, the commercial promise of the NEMAT technology will be preliminarily established.

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