DNA Extraction Service

小鼠DNA的筛选是评估在我们的殖民地出生的小鼠的关键的第一步。由DNA确定的遗传特征用于继续育种选择，选择用于实验的动物，并确保保持近交系小鼠的遗传完整性。使用蛋白水解酶消化尾部样品，并使用Autogen GenePrep DNA分离机器人分离DNA。在2012财年，已处理了70，000多个样本。这是一个高度自动化的过程，非常具有成本效益。消耗性成本/尾部约为0.50美元。BioQual合同的监督包括与合同工作人员的日常对话和适当时的访问。在过去一年中，合同费用一直在预算限度内。

The screening of mouse DNA is a critical first step in evaluating mice born in our colonies. The genetic characteristics determined by the DNA is used to continue selection for breeding, to choose animals to utilize in experiments, and to assure the maintenance of genetic integrity of inbred strains of mice. Tail samples are digested using a proteolytic enzyme and the DNA is isolated utilizing an Autogen GenePrep DNA isolation robot. During FY12 over 70,000 samples have been processed. This is a highly automated process and is very cost effective. Expendable costs/tail are approximately $0.50. Oversight of the BioQual contract consists of daily conversations with contract staff and visits when appropriate. Contract expenses have been within budget limits during the past year.