The rules governing combined rod and cone photoreceptor signalling in visual pathways

视觉通路中杆状和锥状光感受器组合信号传导的规则

• 批准号: DP140100333
• 负责人: Prof Andrew Zele
• 金额: $ 18.16万
• 依托单位: Queensland University of Technology
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2017-07-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP140100333
• 关键词: rules; governing; combined; rod; cone

The research program investigates vision at dim (mesopic) light levels where rod and cone photoreceptors simultaneously transmit visual information. The interaction between rod and cone signals is not trivial because their different amplitudes, timings and delays significantly change the perceptual qualities of our visual experience. The research addresses fundamental questions about how the retina and brain integrate disparate signals from the rods and cones to produce a homogenous visual percept. New psychophysical and electroretinographic paradigms will independently control the retinal photoreceptors to resolve the long standing problem of how noise modifies signalling and information flow between the retina and visual cortex.

该研究项目调查了在昏暗（中间视觉）光水平下的视觉，其中杆和锥光感受器同时传输视觉信息。视杆细胞和视锥细胞信号之间的相互作用并不是微不足道的，因为它们不同的幅度、时间和延迟显著地改变了我们视觉体验的感知质量。这项研究解决了视网膜和大脑如何整合来自视杆细胞和视锥细胞的不同信号以产生同质视觉感受的基本问题。新的心理物理和视网膜电图范例将独立控制视网膜光感受器，以解决噪声如何改变视网膜和视觉皮层之间的信号和信息流的长期问题。