Melanopsin function in humans

黑视蛋白在人类中的功能

• 批准号: DP170100274
• 负责人: Prof Andrew Zele
• 金额: $ 16.57万
• 依托单位: Queensland University of Technology
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP170100274
• 关键词: Melanopsin; function; humans

This project aims to understand melanopsin signalling in humans. A newly discovered retinal ganglion cell class expresses the melanopsin photopigment. Melanopsin signalling controls neural functions for light dependent image formation and non-image forming processes. Many of these are unknown in humans. This project will use a 5-primary photostimulator to define how melanopsin controls these processes in humans. The outcomes are expected to advance understanding of human vision. This could provide avenues for using light to increase active participation in society and improve health and well-being, and strategies to assess human vision and the body’s internal clock.

该项目旨在了解人类的黑视素信号。一种新发现的表达黑视素的视网膜神经节细胞。黑视蛋白信号传导控制光依赖性图像形成和非图像形成过程的神经功能。其中许多是人类未知的。该项目将使用5初级光刺激器来定义黑视素如何控制人类的这些过程。这些成果有望促进对人类视觉的理解。这可以提供利用光来增加积极参与社会和改善健康和福祉的途径，以及评估人类视力和身体内部时钟的策略。