Training in Environmental Toxicology of Complex Diseases

描述（由申请人提供）：亚利桑那大学毒理学研究生项目在培养博士科学家方面有着长期的卓越声誉。我们的许多毕业生现在是学术界、工业界和政府的领导人。目前的学员是通过全校范围的竞争选拔出来的。研究生课程已经从基于系统的毒理学经验发展到训练学生应用最先进的技术来解决影响各种器官系统复杂疾病的环境毒性机制。22名培训资助教师的尖端基础科学研究项目，亚利桑那大学与西南环境健康科学中心和Bio5联合开发的最先进技术，以及NIEHS超级基金项目和美墨两国中心开展的转化方法，为研究生和博士后的培训提供了一个非常刺激的环境。我们的培训资助学院和我们最先进的设施核心的互动研究将培训环境从单一的实验室为导向的领域扩展到一个多学科的经验，强烈支持合作研究。学校为博士一年级学生提供财政支持，为竞争选拔博士预科生提供了大量高素质的候选人。博士前的训练是通过课程作业、实验室研究和补充丰富活动的结合来实现的。博士后学员参与创新研究项目，培养口头、书面交流和监督方面的专业技能。在过去的五年里，课程的变化与培训资助学院在利用最先进的技术进行研究项目方面不断发展的专业知识相一致。本中心招收了3名高级教师（教授）和3名初级教师（助理教授）进入培训资助项目，大大增强了以机械为基础的分子毒理学培训的核心实力。为进一步鼓励跨学科/多学科的研究和培训方法，我们已开设培训补助金，供全校范围内的学生选择。我们的项目非常成功，对毕业生的明确需求，我们对学员和博士后的领导技能的重视，对毒理学感兴趣的学生数量的增加，大量的机构承诺，我们教师强大而资金充足的研究项目，以及卓越的培训环境，都证明了我们继续支持NIEHS的要求。

DESCRIPTION (provided by applicant): The Toxicology Graduate Program at the University of Arizona has a long-standing reputation for excellence in training Ph.D. scientist. Many of our graduates are now leaders in academia, industry, and government. Current trainees are now selected through a University-wide competition. The graduate program has evolved from a systems-based toxicology experience to training students to apply state-of-the art techniques to solve mechanisms of environmental toxicity affecting complex diseases in various organ systems. The cutting-edge basic science research programs of 22 Training Grant Faculty members, state-of-the-art technologies developed at the University of Arizona in association with the Southwest Environmental Health Sciences Center and Bio5, and translational approaches undertaken by our NIEHS Superfund Program and US-Mexico Binational Center provide an exceptionally stimulating environment for the training of graduate students and postdoctoral fellows. The interactive research of our Training Grant Faculty and our state-of-the-art Facility Cores extend the training environment from a single laboratory-oriented domain into a multidisciplinary experience strongly supportive of collaborative research. The University provides financial support for first year Ph.D. students, providing a large pool of highly qualified candidates for competitive selection of predoctoral trainees. Predoctoral training is achieved through a combination of coursework, laboratory research, and supplemental enrichment activities. Postdoctoral trainees participate in innovative research programs and are guided to develop professional skills in oral and written communication and in supervision. Over past five years, the curricular changes parallel the evolving expertise of the Training Grant Faculty in utilizing state-of-the-art technology for research projects. We have recruited 3 senior (Professor) and 3 junior (Assistant Professor) faculty into the Training Grant, which significantly enhances the strength in the core of mechanistic based molecular toxicology training. We have opened the Training Grant for University-wide selection to further stimulate interdisciplinary/multidisciplinary approaches in research and training. The request for continuation of NIEHS support is validated by the highly successful nature of our program, the clear demand for our graduates, the strong emphasis we place on leadership skills for our trainees and postdoctoral fellows, the increasing number of students interested in toxicology, substantial institutional commitment, strong and well-funded research programs of our faculty, and the excellence of the training environment.