Electronic system for wireless monitoring of patient medication adherence
用于无线监测患者用药依从性的电子系统
基本信息
- 批准号:8452976
- 负责人:
- 金额:$ 14.58万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2012
- 资助国家:美国
- 起止时间:2012-09-26 至 2014-02-28
- 项目状态:已结题
- 来源:
- 关键词:AdherenceAdoptionAlgorithmsAntibioticsBehaviorBehavior TherapyCar PhoneCaregiversCellular PhoneCessation of lifeChronic DiseaseClinicalCommunicationComputer softwareComputersCuesDataDevelopmentDevicesDoseDrug PrescriptionsElectronicsEventFeedbackHIVHealthHealth Care CostsHealth ProfessionalHealth systemHealthcare SystemsHome environmentHospitalizationHumanHuman ResourcesInsurance CarriersInterventionJournalsLearningLightMeasuresMemoryMethodsMonitorMonitoring Clinical TrialsMorbidity - disease rateMovementOutcomePatient MonitoringPatientsPerformancePersonsPharmaceutical PreparationsPharmacologic SubstancePhysiciansPilot ProjectsProcessRecordsRegimenReportingRiskRunningSiteSleepSystemTechnologyTelephoneTestingTimeTreatment outcomeUpdateUse EffectivenessWireless TechnologyWorkWritingcompliance behaviordesigndigitaleffective interventionfoothigh riskimprovedinnovationmedication complianceoperationpatient populationprematurepreventtooltransmission processviral resistance
项目摘要
DESCRIPTION (provided by applicant): Our objective is to provide patients and physicians with an effective new tool to increase patient compliance (aka adherence) to prescription drug regimens. Poor patient compliance diminishes patients' health, increases preventable morbidity, and results in avoidable healthcare costs. Even in monitored clinical trials, compliance is often poor and interventions to improve compliance are expensive and have mixed results. For some patient populations, like those with HIV, poor medication compliance can result in a rapid decline in health, increased resistance of the virus to antibiotics, and premature death. We propose a wireless dosing reporting system that will provide physicians and caregivers timely and accurate medication reminder and compliance reporting. The system will be designed to take advantage of wireless technologies like Bluetooth and the cellular phone system to provide dosing data to a patient monitor at little expense to the patient. The outcome of the work will be an electronic circuit that attaches to a standard medication container that can transmit dosing data to a patients' smartphone. A mobile phone application will collect the dosing data and transmit that information to a monitoring site in real time. Our company has dose reminding and recording circuitry that attaches to standard medication containers without interfering with the packaging or contents of the container. At dose time, a light prompts the patient to take their medication. The circuitry records the date and time of all dosing events as determined through algorithms designed to distinguish the difference between a dosing event and incidental movement of the container. We will extend the capability of the DoseCue circuitry to include wireless transmission of the dosing data stored in the circuitry's memory to a smartphone via Bluetooth communication. A mobile application installed on patients' phones will collect the dosing data from the circuitry at specific times and transmit the information to a central processing point, allowing for intervention in real time as needed. The system will be tested to verify ease of use, effectiveness in transmitting data wirelessly across the cell phone network, and accuracy of patient dosing data. The system provides real-time feedback of patients' home medication dosing to their doctor, caregiver, or other authorized person without requiring action by the patient (such as connecting to a computer via USB). By providing real-time warnings when a patient is not taking their medication as prescribed, a patient monitor can intervene before negative health effects occur. A completed wireless compliance system will benefit patient health and reduce healthcare costs.
PUBLIC HEALTH RELEVANCE: Poor medication dosing results in a decline in patient health and creates an unnecessary burden to the healthcare system. The DoseCue Mobile system provides a simple, direct method for providing real-time oversight of patient dosing behavior. The ability to intervene when patient dosing is poor can directly improve treatment outcomes and prevent serious health problems while reducing healthcare costs for high risk patients.
描述(由申请人提供):我们的目标是为患者和医生提供一种有效的新工具,以提高患者对处方药方案的依从性(即依从性)。患者依从性差会损害患者的健康,增加可预防的发病率,并导致可避免的医疗费用。即使在监测的临床试验中,依从性也往往很差,改善依从性的干预措施费用昂贵,结果好坏参半。对于一些患者群体,如艾滋病毒感染者,药物依从性差可能导致健康状况迅速下降,病毒对抗生素的耐药性增加,以及过早死亡。我们提出了一个无线给药报告系统,将提供医生和护理人员及时,准确的用药提醒和遵守报告。该系统将被设计为利用无线技术,如蓝牙和蜂窝电话系统,以向患者监护仪提供给药数据,而患者的费用很低。这项工作的成果将是一个电子电路,它连接到一个标准的药物容器,可以将剂量数据传输到患者的智能手机。移动的电话应用程序将收集剂量数据并将该信息真实的传输到监测站点。我们公司有剂量提醒和记录电路,连接到标准的药物容器,而不干扰包装或容器的内容物。在服药时间,一盏灯提示病人服药。该电路记录通过算法确定的所有定量给料事件的日期和时间,该算法设计用于区分定量给料事件和容器的偶然移动之间的差异。我们将扩展DoseCue电路的功能,以包括通过蓝牙通信将存储在电路存储器中的给药数据无线传输到智能手机。安装在患者手机上的移动的应用程序将在特定时间从电路收集给药数据,并将信息传输到中央处理点,从而允许根据需要进行真实的干预。将对该系统进行测试,以验证其易用性、通过手机网络无线传输数据的有效性以及患者给药数据的准确性。该系统向医生、护理人员或其他授权人员提供患者家庭用药剂量的实时反馈,而无需患者采取行动(例如通过USB连接到计算机)。通过在患者未按规定服药时提供实时警告,患者监护仪可以在负面健康影响发生之前进行干预。一个完整的无线合规系统将有利于患者健康并降低医疗成本。
公共卫生相关性:不良的药物剂量会导致患者健康状况下降,并给医疗保健系统带来不必要的负担。DoseCue移动的系统提供了一种简单、直接的方法,用于实时监督患者给药行为。当患者剂量不足时进行干预的能力可以直接改善治疗结果并预防严重的健康问题,同时降低高风险患者的医疗保健成本。
项目成果
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