Training in Anti-Cancer Drug Development
Training in Anti-Cancer Drug Development
批准号:
8311779
负责人:
JAMES T. STIVERS
金额:
$54.63万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
1978
资助国家:
美国
项目状态:
已结题
起止时间:
1978-09-30 至 2014-06-30
中文摘要
这是一份申请,要求继续支持抗癌药物开发培训基金,
英文摘要
This is an application requesting continued support for the Anti-Cancer Drug Development training grant,
T32 CA09243, presently in its 30th year. The program is administered by the Department of Pharmacology
& Molecular Sciences of the Johns Hopkins University, School of Medicine and its objective is to prepare
pre- and postdoctoral students for research and teaching careers in the area of cancer-related drug
development. *Predoctoral training provides highly qualified students with an integrated curriculum including
course work and research. A reorganized and envigorated series of core courses in the basic sciences is
taken during the first year and includes molecular biology and genomics, biochemical and biophysical
principles, macromolecular structure and analysis, organic mechanisms in biology, cell structure and
dynamics, pathways and regulation, and bioinformatics. Students receive additional instruction and
exposure to pharmacology and oncology through a required graduate pharmacology course in the second
year, and through elective courses, seminars, and journal clubs. Predoctoral trainees select a faculty
preceptor and research project during their first two years, and devote most of their time after that to their
thesis research and gaining experience with written and oral presentation of their work. Postdoctoral
trainees devote most of their time to research carried out more independently, but with appropriate guidance
from faculty mentors, for periods of one to three years. *The training program is interdisciplinary and brings
together faculty from eight departments: Pharmacology & Molecular Sciences, Oncology, Biophysics &
Biophysical Chemistry, Chemistry, Molecular Biology & Genetics, Cell Biology, Urology, and Environmental
Health Sciences. Extensive faculty interaction is promoted by four new research Centers established by the
Institute of Basic Biomedical Sciences and by common research interests. Extensive and productive
student-faculty and student-student interactions are promoted by seminars, journal clubs, and by student-
related activities such as recruiting weekends, research retreats, student-faculty dinners, and teaching, in
addition to the laboratory research experience. *Since its beginning in 1979, this training program has
supported over 130 pre-and postdoctoral trainees, most of whom have gone on to careers in science and
many of whom have assumed leadership roles in the field of cancer research.
期刊论文(63)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
DOI:
10.1158/1535-7163.mct-12-0618
发表时间:
2013-06
期刊:
Molecular cancer therapeutics
影响因子:
5.7
作者:
[Zinn RL, Gardner EE, Marchionni L, Murphy SC, Dobromilskaya I, Hann CL, Rudin CM]
通讯作者:
Rudin CM
Direct protective effect of NAD(P)H:quinone reductase against menadione-induced chemiluminescence of postmitochondrial fractions of mouse liver.
NAD(P)H:醌还原酶对甲萘醌诱导的小鼠肝脏线粒体后部分化学发光的直接保护作用。
DOI:
--
发表时间:
1987
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
[Prochaska,HJ, Talalay,P, Sies,H]
通讯作者:
Sies,H
Novel induction by herpes simplex virus of hybrid interferon gene transcripts driven by the strong cytomegalovirus IE94 promoter.
单纯疱疹病毒由强巨细胞病毒 IE94 启动子驱动的杂合干扰素基因转录物的新诱导。
DOI:
10.1128/jvi.61.3.819-828.1987
发表时间:
1987
期刊:
Journal of virology
影响因子:
5.4
作者:
[Mosca,JD, Jeang,KT, Pitha,PM, Hayward,GS]
通讯作者:
Hayward,GS
DOI:
10.1083/jcb.101.1.85
发表时间:
1985-07
期刊:
JOURNAL OF CELL BIOLOGY
影响因子:
7.8
作者:
[CHEN, JW, MURPHY, TL, WILLINGHAM, MC, PASTAN, I, AUGUST, JT]
通讯作者:
AUGUST, JT
Structural and functional components in normal and hyperplastic canine prostates.
正常和增生犬前列腺的结构和功能成分。
DOI:
--
发表时间:
1984
期刊:
Progress in clinical and biological research
影响因子:
--
作者:
[Isaacs,WB]
通讯作者:
Isaacs,WB
共 43 条
Discovery of Chemical Probes of SAMHD1 for Modulation of Cancer Therapy and the Immune System
-
批准号:10163140
-
项目类别:
-
资助金额:$37.46万
-
财政年份:2020
-
负责人:JAMES T. STIVERS
-
依托单位:
Discovery of Chemical Probes of SAMHD1 for Modulation of Cancer Therapy and the Immune System
-
批准号:10396629
-
项目类别:
-
资助金额:$36.71万
-
财政年份:2020
-
负责人:JAMES T. STIVERS
-
依托单位:
Discovery of Chemical Probes of SAMHD1 for Modulation of Cancer Therapy and the Immune System
-
批准号:10650716
-
项目类别:
-
资助金额:$36.71万
-
财政年份:2020
-
负责人:JAMES T. STIVERS
-
依托单位:
Fate of Invisible U/A Base Pairs Within HIV DNA in Myeloid Phagocytic Cells
-
批准号:9138025
-
项目类别:
-
资助金额:$40.15万
-
财政年份:2016
-
负责人:JAMES T. STIVERS
-
依托单位:
Persistence and Fate of Invisible U/A Pairs in HIV-1 Proviral DNA
-
批准号:8790165
-
项目类别:
-
资助金额:$16.65万
-
财政年份:2014
-
负责人:JAMES T. STIVERS
-
依托单位:
Persistence and Fate of Invisible U/A Pairs in HIV-1 Proviral DNA
-
批准号:8910622
-
项目类别:
-
资助金额:$15.1万
-
财政年份:2014
-
负责人:JAMES T. STIVERS
-
依托单位:
Purchase of a 600 MHz NMR Console and Probes
-
批准号:8051342
-
项目类别:
-
资助金额:$55.0万
-
财政年份:2011
-
负责人:JAMES T. STIVERS
-
依托单位:
Fluorescence-Based Screen for Human DNA 5-Cytosine-methyltransferase 1
-
批准号:8089372
-
项目类别:
-
资助金额:$3.98万
-
财政年份:2010
-
负责人:JAMES T. STIVERS
-
依托单位:
Fluorescence-Based Screen for Human DNA 5-Cytosine-methyltransferase 1
-
批准号:8010339
-
项目类别:
-
资助金额:$4.1万
-
财政年份:2010
-
负责人:JAMES T. STIVERS
-
依托单位:
High Throughput Assay:Topoisomerase Enzyme Targets (RMI)
-
批准号:7022489
-
项目类别:
-
资助金额:$8.15万
-
财政年份:2005
-
负责人:JAMES T. STIVERS
-
依托单位:
Mechanistic Biology of Topoisomerase 1B
-
批准号:6890397
-
项目类别:
-
资助金额:$27.8万
-
财政年份:2003
-
负责人:JAMES T. STIVERS
-
依托单位:
Chemical Approaches to DNA Topoisomerase Inhibition and Function
-
批准号:8073202
-
项目类别:
-
资助金额:$28.13万
-
财政年份:2003
-
负责人:JAMES T. STIVERS
-
依托单位:
Mechanistic Biology of Topoisomerase 1B
-
批准号:7492490
-
项目类别:
-
资助金额:$9.07万
-
财政年份:2003
-
负责人:JAMES T. STIVERS
-
依托单位:
Mechanistic Biology of Topoisomerase 1B
-
批准号:6752139
-
项目类别:
-
资助金额:$27.8万
-
财政年份:2003
-
负责人:JAMES T. STIVERS
-
依托单位:
Mechanistic Biology of Topoisomerase 1B
-
批准号:7059445
-
项目类别:
-
资助金额:$27.14万
-
财政年份:2003
-
负责人:JAMES T. STIVERS
-
依托单位:
Chemical Approaches to DNA Topoisomerase Inhibition and Function
-
批准号:7459992
-
项目类别:
-
资助金额:$28.7万
-
财政年份:2003
-
负责人:JAMES T. STIVERS
-
依托单位:
Mechanistic Biology of Topoisomerase 1B
-
批准号:6672728
-
项目类别:
-
资助金额:$27.8万
-
财政年份:2003
-
负责人:JAMES T. STIVERS
-
依托单位:
Chemical Approaches to DNA Topoisomerase Inhibition and Function
-
批准号:7619124
-
项目类别:
-
资助金额:$28.7万
-
财政年份:2003
-
负责人:JAMES T. STIVERS
-
依托单位:
MECHANISMS AND TRANSITION STATES FOR DNA GLYCOSYLASES
-
批准号:6151196
-
项目类别:
-
资助金额:$15.76万
-
财政年份:1998
-
负责人:JAMES T. STIVERS
-
依托单位:
DNA Repair in Non-Dividing Macrophages Through Reversible Go to pseudo-G1 Cell Cycle Transitions
-
批准号:10247072
-
项目类别:
-
资助金额:$45.85万
-
财政年份:1998
-
负责人:JAMES T. STIVERS
-
依托单位:
海外基金