Ripple Effect of Lifestyle Intervention During Pregnancy on Partners' Weight

描述(申请人提供)：针对超重个人的生活方式干预措施可以对家庭中未经治疗的超重伴侣产生积极的“涟漪”效应。有趣的是，当干预措施针对女性时，对伴侣体重的连锁反应似乎最明显。妇女，尤其是母亲，仍然是家庭的主要“营养看门人”。尽管人们普遍认为，母亲身份是行为改变的强大动力，但到目前为止，还没有研究调查针对母亲孕期体重增加的产前生活方式干预的“涟漪”影响。这项拟议研究的主要目的是确定预防超重/肥胖孕妇妊娠体重过度增加的生活方式干预措施是否对家庭中未接受治疗的伴侣产生积极的“连锁反应”。这项拟议的研究是LIFE-MOMS联盟的两个随机第三阶段临床试验(1U01HL114377-01，Pi Phelan；3U01DK094418-01S1，Pis Martin和Redman)的附属研究，这两个试验正在检查多组分生活方式干预措施的有效性，以防止总共650名超重/肥胖妇女过度妊娠体重增加。在这项辅助研究中，伴侣的体重、家庭环境和心理社会行为将在其怀孕伴侣怀孕~13周(研究条目)、怀孕35周以及产后6个月和12个月时进行评估。我们假设，与标准护理相比，随机接受生活方式干预的孕妇的伴侣将通过以下方式减轻更多体重 12个月。次要目的是检查伴侣在体重控制行为、家庭环境和心理社会参数方面的改善。该项目具有很高的创新性，因为它利用了现有的资助研究，是第一个研究多成分产前干预的连锁反应的研究。该项目的影响也很大，因为怀孕是家庭行为和环境变化的强大动机；如果产生积极的连锁反应，肥胖症治疗和预防领域可能会超越对个人层面的关注，转向生活方式干预措施往往未被认识到的人际影响。

DESCRIPTION (provided by applicant): Lifestyle interventions targeting overweight individuals can produce positive "ripple" effects on untreated overweight partners in the home. Interestingly, ripple effects on partners' weight appear most pronounced when the interventions target women. Women, and mothers in particular, remain the primary "nutritional gatekeepers" of the home. Despite widespread recognition that motherhood is a powerful motivator for behavior changes, no study to date has examined the "ripple" effects of prenatal lifestyle interventions that target mothers' gestational weight gain. The primary aim of the proposed study is to determine whether lifestyle interventions to prevent excessive gestational weight gain in overweight/obese pregnant women have positive "ripple" effects on untreated partners in the home. The proposed study is ancillary to two randomized phase III clinical trials in the LIFE-moms consortium (1U01HL114377-01, PI Phelan; 3U01DK094418-01S1, PIs Martin and Redman) that are examining the efficacy of multi-component lifestyle interventions to prevent excessive gestational weight gain in a total of 650 overweight/obese women. In this ancillary study, partners' weight, home environment, and psychosocial behaviors will be assessed when their pregnant partners are ~13 weeks gestation (study entry), 35 weeks gestation and at 6 and 12 months postpartum. We hypothesize that partners of pregnant women randomized to the lifestyle intervention, relative to those of standard care, will have greater weight losses through 12-months. Secondary aims examine partner improvements in weight control behaviors, the home environment, and psychosocial parameters. This project is highly innovative, as it capitalizes on existing funded research and is the first study to examine ripple effects of multicomponent prenatal interventions. The project also has high impact, as pregnancy is a powerful motivator for behavior and environmental changes in the home; and, if positive ripple effects occur, the field of obesity treatment and prevention could move beyond focus on individual level to the often unrecognized interpersonal effects of lifestyle interventions.