Clinical Hematology Research Career Development Program (K12) at Hopkins

描述（由申请人提供）：本提案旨在继续在约翰霍普金斯医疗机构（JHMI）的良性血液学和输血医学临床血液学职业发展计划。良性血液学和输血医学的下一代临床研究人员将需要包括具有技能，态度，早期研究培训和经验的个人，以利用这些学科的快速发展进步。在开发该计划时，我们将使用已建立的研究基础设施，包括独立的儿科血液学，内科和输血医学部门，致力于良性血液疾病的护理和研究，以及我们在约翰霍普金斯大学医学院和约翰霍普金斯大学彭博公共卫生学院的临床研究研究生培训计划（GTPCI）。我们的具体目标是：a）继续确定，招聘，培训和发展创造性和成功的临床研究人员，有能力与参与临床研究的多学科团队互动，参与和领导，解决复杂问题，并成为儿科，青少年和成人良性血液学和输血医学的国家领导者; B）为学员提供在这些领域从事临床研究所需的技能、知识、态度和经验，使其在学术生涯中取得成功。该培训将包括接触国家和国际领导人以及成功进行临床研究所需的多个学科的课程，包括良性血液学、输血医学、临床试验设计、流行病学、统计学、研究伦理和人类受试者保护; c） 提供丰富的指导环境。我们将整合JHMI的多个研究资源和研究人员，为学员提供最佳的研究经验和培训。我们将继续把我们的努力集中在六个领域，我们认为有我们的机构内的特别优势：骨髓衰竭和干细胞生物学，镰状细胞病（SCD），骨髓增生性疾病，输血医学，结果研究和遗传学。我们将与几位知名研究者和导师合作，为学员开发良性血液学的结构化课程和强有力的指导研究经验。仔细和广泛的指导将是这些努力的基石，接触到尖端的研究经验。通过该计划，我们的最终目标是提供一个临床研究人员的干部，谁将成为创造性的，独立的调查，照顾病人，并承担良性临床血液学的领导作用。

DESCRIPTION (provided by applicant): This proposal seeks to continue a Clinical Hematology Career Development Program in benign hematology and transfusion medicine at the Johns Hopkins Medical Institutions (JHMI). The next generation of clinical researchers in benign hematology and transfusion medicine will need to include individuals with the skills, attitudes, early research training and experience to capitalize on rapidly developing progress in these disciplines. In developing this program, we will use established research infrastructure, including free-standing Divisions of Hematology in Pediatrics, Internal Medicine and Transfusion Medicine that are dedicated to the care and study of benign hematologic disorders, as well as our Graduate Training Program in Clinical Investigation (GTPCI) at the Johns Hopkins University School of Medicine and Johns Hopkins University Bloomberg School of Public Health. Our specific aims are: a) To continue to identify, recruit, train and develop creative and successful clinical investigators, with the capability to interact with, participate in, and lead multidisciplinary teams involved in clinical research, address complex problems and become national leaders in pediatric, adolescent and adult benign hematology and transfusion medicine; b) To provide trainees with the requisite skills, knowledge, attitude and experience for successful academic careers in clinical research in these areas. This training will include exposure to national and international leaders and curriculum in the multiple disciplines necessary for successful clinical research, including benign hematology, transfusion medicine, clinical trials design, epidemiology, statistics, research ethics and human subjects protection; c) To provide a rich mentoring environment. We will integrate multiple research resources and investigators available at the JHMI to provide optimal exposure of trainees to research experiences and training. We will continue to focus our efforts in six areas where we feel there is particular strength within our institution: bone marrow failure and stem cell biology, sickle cel disease (SCD), myeloproliferative disorders, transfusion medicine, outcomes research and genetics. We will work with several established investigators and mentors to develop a structured curriculum in benign hematology and strong mentored research experiences for trainees. Careful and extensive mentoring will be the cornerstone of these efforts, with exposure to cutting edge research experiences. Through this program, we ultimately aim to provide a cadre of clinical researchers, who will become creative, independent investigators, care for patients and assume leadership roles in benign clinical hematology.