Clinical Hematology Research Career Development Program (K12) at Hopkins

描述（由申请人提供）：本提案旨在继续约翰霍普金斯医疗机构（JHMI）良性血液学和输血医学的临床血液学职业发展计划。良性血液学和输血医学的下一代临床研究人员将需要包括具有技能、态度、早期研究培训和经验的个人，以利用这些学科快速发展的进展。在开发这个项目的过程中，我们将利用现有的研究基础设施，包括致力于良性血液疾病的护理和研究的儿科血液学、内科和输血医学的独立部门，以及我们在约翰霍普金斯大学医学院和约翰霍普金斯大学彭博公共卫生学院的临床研究研究生培训计划（GTPCI）。我们的具体目标是：a)继续识别、招募、培训和发展具有创造性和成功的临床研究人员，具有与临床研究的多学科团队互动、参与和领导的能力，解决复杂的问题，并成为儿科、青少年和成人良性血液学和输血医学的国家领导者；b)为受训者提供必要的技能、知识、态度和经验，使他们在这些领域的临床研究中取得成功。该培训将包括接触国内和国际领导人以及成功临床研究所需的多学科课程，包括良性血液学、输血医学、临床试验设计、流行病学、统计学、研究伦理和人类受试者保护；c)

DESCRIPTION (provided by applicant): This proposal seeks to continue a Clinical Hematology Career Development Program in benign hematology and transfusion medicine at the Johns Hopkins Medical Institutions (JHMI). The next generation of clinical researchers in benign hematology and transfusion medicine will need to include individuals with the skills, attitudes, early research training and experience to capitalize on rapidly developing progress in these disciplines. In developing this program, we will use established research infrastructure, including free-standing Divisions of Hematology in Pediatrics, Internal Medicine and Transfusion Medicine that are dedicated to the care and study of benign hematologic disorders, as well as our Graduate Training Program in Clinical Investigation (GTPCI) at the Johns Hopkins University School of Medicine and Johns Hopkins University Bloomberg School of Public Health. Our specific aims are: a) To continue to identify, recruit, train and develop creative and successful clinical investigators, with the capability to interact with, participate in, and lead multidisciplinary teams involved in clinical research, address complex problems and become national leaders in pediatric, adolescent and adult benign hematology and transfusion medicine; b) To provide trainees with the requisite skills, knowledge, attitude and experience for successful academic careers in clinical research in these areas. This training will include exposure to national and international leaders and curriculum in the multiple disciplines necessary for successful clinical research, including benign hematology, transfusion medicine, clinical trials design, epidemiology, statistics, research ethics and human subjects protection; c) To provide a rich mentoring environment. We will integrate multiple research resources and investigators available at the JHMI to provide optimal exposure of trainees to research experiences and training. We will continue to focus our efforts in six areas where we feel there is particular strength within our institution: bone marrow failure and stem cell biology, sickle cel disease (SCD), myeloproliferative disorders, transfusion medicine, outcomes research and genetics. We will work with several established investigators and mentors to develop a structured curriculum in benign hematology and strong mentored research experiences for trainees. Careful and extensive mentoring will be the cornerstone of these efforts, with exposure to cutting edge research experiences. Through this program, we ultimately aim to provide a cadre of clinical researchers, who will become creative, independent investigators, care for patients and assume leadership roles in benign clinical hematology.