The Role of Protective Factors on Outcomes for Latinos with Schizophrenia

描述(由申请人提供)：家庭心理教育干预在精神分裂症患者及其家庭成员中显示出显著的临床和功能结果。特别是，纳入保护性因素的干预措施 文化适应的拉丁裔被发现对这一文化群体有利，这表明保护性因素在支持治疗效果方面具有影响。保护性因素，如家庭水平 消费者和家庭利用HOPE来改善因疾病而产生的困难体验。然而，很少有研究考察保护性因素在家庭心理教育干预中的作用。此外，家庭心理教育研究倾向于将复发作为治疗成功的标准，从而掩盖了其他潜在的干预好处。 由于文化在健康感知中发挥着重要作用，因此检查消费者和家庭成员对治疗结果的看法是很重要的。拟议的研究试图通过审查显著的保护因素(家庭凝聚力和适应性、家庭温暖、家庭希望程度)对消费者(症状、生活质量)和关键家庭成员(负担、疾病知识)的治疗结果的积极影响，来解决这些知识差距。这项研究将集中于以下目标：(1)与那些照常接受治疗的消费者和家庭相比，检查保护因素对参加基于文化的家庭干预的消费者和家庭结果的影响；(2)确定消费者和家庭成员在干预完成后对显著的临床和功能结果的文化具体看法。为了实现这些目标，本研究将通过文化交流框架提供信息，并将利用顺序解释性混合方法设计，使用来自NIMH资助的针对拉丁裔基于文化的家庭心理教育模式的干预发展研究的二级定量数据(N=)。第一阶段将审查保护因素随着时间的推移对消费者和家庭结果的影响，然后对保护因素对干预结果的影响进行调解分析(目标1)。研究结果将用于第二阶段的研究，在此期间，将收集和分析来自父母研究的一部分参与者(20名消费者和20名关键家庭成员)的定性数据，以探索文化上对健康的具体看法，以及干预措施如何影响对疾病、治疗和服务利用的看法(目标2)。本研究旨在阐明基于文化的心理教育干预如何增强文化显著的保护因素，并进一步支持这种干预措施在患有精神分裂症的拉丁裔消费者及其家人中的使用和有效性。

DESCRIPTION (provided by applicant): Family psychoeducation interventions have demonstrated significant clinical and functional outcomes among consumers with schizophrenia and their family members. In particular, interventions that incorporate protective factors with low acculturated Latinos have been found to benefit this cultural group, suggesting that protective factors are influential in supporting treatment effects. Protective factors such as family level of hope are used by consumers and families to improve difficult experiences resulting from the illness. However, few studies have examined the role of protective factors in family psychoeducation interventions. Moreover, family psychoeducation studies tend to focus on relapse as a criterion for treatment success, thus obscuring other potential intervention benefits. Because culture plays an instrumental role in perceptions of wellness, it is important to examine consumer and family member perceptions of treatment outcomes. The proposed study seeks to address these gaps in knowledge by examining the positive influence of salient protective factors (family cohesion and adaptability, family warmth, family level of hope) on treatment outcomes for consumers (symptoms, quality of life) and key family members (burden, knowledge of the illness). The study will focus on the following aims: (1) examine the effects of protective factors on outcomes for consumers and families who participated in a culturally based family intervention compared to those who received treatment as usual; and (2) identify culturally specific perceptions of salient clinical and functional outcomes experienced by consumers and family members following completion of the intervention. To achieve these aims, this study will be informed by a cultural exchange framework and will utilize a sequential explanatory mixed-method design with secondary quantitative data (N = 64) from an NIMH-funded intervention development study of a culturally based family psychoeducation model for Latinos. Phase 1 will involve examining the effects of protective factors on consumer and family outcomes over time, followed by mediation analyses of the influence of protective factors on intervention outcomes (Aim 1). Findings will inform the second phase of the study, during which qualitative data from a subset of participants (20 consumers and 20 key family members) from the parent study will be collected and analyzed to explore culturally specific perceptions of wellness and how the intervention influenced perceptions of the illness, treatment, and service utilization (Aim 2). This study seeks to elucidate how culturally based psychoeducation interventions may enhance culturally salient protective factors and further support the use and effectiveness of this intervention for Latino consumers with schizophrenia and their families.