Developing and Improving Institutional Animal Resources (G20)

描述（由申请人提供）：堪萨斯大学实验动物资源是一个集中管理的动物设施，为KUMC的所有动物用户提供服务。动物护理和使用计划是一个迅速扩大的研究计划的组成部分。癌症研究是堪萨斯大学医学中心的首要任务。在过去的几年里，这个项目招募了25名新教员。2012年7月12日，KUMC获得了国家癌症研究所的指定。近十年的努力为堪萨斯大学癌症中心带来了顶尖的癌症研究人员，并为该地区提供了数百万美元的癌症研究资金。动物护理和使用项目有必要支持研究企业的这种增长。根据最近动物护理和使用协议的批准，以及先进的动物采购请求，我们预计明年动物住房将接近其容量。这项应用的基本原理是基于对主要动物住房场地，研究支持设施大楼更可靠的暖通空调系统的需求。因此，本项目的目标是更换地面至一楼的空气处理机组，安装一个辅助机组作为机械故障或维护期间的备份，并更换恒容控制箱。这次建筑升级将使KUMC达到第八版指南规定的环境参数标准，包括在无病原体和ABSL-2动物菌落中适当的动物室压力。

DESCRIPTION (provided by applicant): The University of Kansas Laboratory Animal Resources is a centrally managed animal facility that provides services to all animal users at KUMC. The animal care and use program is an integral part of a rapidly expanding research programs. Cancer research is the #1 priority for KU Medical Center. In the past few years, twenty-five new faculties were recruited to this program. On July 12, 2012, KUMC received the National Cancer Institute designation. Nearly a decade-long effort has brought top cancer researchers to KU Cancer Center, and millions of dollars in cancer research funding to the region. The animal care and use program has essential needs to support this growth in the research enterprise. We anticipate the animal housing buildings will be near its capacity next year based on recent animal care and use protocol approvals, and advanced animal procurement requests. The rationale for this application is based on a need for more reliable HVAC system in the principal animal housing site, the Research Support Facility building. Thus, the goals of this project are to replace the ground-first floor air handling unit, install an auxilary unit to serve as back up in times of mechanical failure or during maintenance, and replace the constant volume control boxes. This building upgrade will enable KUMC to meet environmental parameter standards prescribed by the 8th edition Guide, including adequate animal room pressurization in the pathogen free and ABSL-2 animal colonies.