Developing and Improving Institutional Animal Resources (G20)

描述（由申请人提供）：堪萨斯大学实验动物资源部是一家集中管理的动物机构，为KUMC的所有动物用户提供服务。动物护理和使用计划是迅速扩大的研究计划的一个组成部分。癌症研究是KU医疗中心的首要任务。在过去的几年里，25个新的院系被招募到这个计划。2012年7月12日，KUMC获得了国家癌症研究所的称号。近十年的努力使顶级癌症研究人员来到KU癌症中心，并为该地区提供了数百万美元的癌症研究资金。动物护理和使用计划有必要支持研究企业的这种增长。根据最近的动物护理和使用方案批准以及先进的动物采购要求，我们预计动物饲养建筑明年将接近其容量。该申请的依据是主要动物饲养场所（研究支持机构大楼）需要更可靠的HVAC系统。因此，该项目的目标是更换一楼的空气处理装置，安装一个辅助装置，在机械故障或维修期间作为备份，并更换定容控制箱。这一建筑升级将使KUMC能够满足第8版指南规定的环境参数标准，包括在无病原体和ABSL-2动物群中适当的动物房加压。

DESCRIPTION (provided by applicant): The University of Kansas Laboratory Animal Resources is a centrally managed animal facility that provides services to all animal users at KUMC. The animal care and use program is an integral part of a rapidly expanding research programs. Cancer research is the #1 priority for KU Medical Center. In the past few years, twenty-five new faculties were recruited to this program. On July 12, 2012, KUMC received the National Cancer Institute designation. Nearly a decade-long effort has brought top cancer researchers to KU Cancer Center, and millions of dollars in cancer research funding to the region. The animal care and use program has essential needs to support this growth in the research enterprise. We anticipate the animal housing buildings will be near its capacity next year based on recent animal care and use protocol approvals, and advanced animal procurement requests. The rationale for this application is based on a need for more reliable HVAC system in the principal animal housing site, the Research Support Facility building. Thus, the goals of this project are to replace the ground-first floor air handling unit, install an auxilary unit to serve as back up in times of mechanical failure or during maintenance, and replace the constant volume control boxes. This building upgrade will enable KUMC to meet environmental parameter standards prescribed by the 8th edition Guide, including adequate animal room pressurization in the pathogen free and ABSL-2 animal colonies.