Stroke National Capital Area Network for Research (SCANR)

描述（由申请人提供）：SCANR，中风国家首都区域研究网络，总部设在华盛顿特区。SCANR由5家已经在中风研究方面进行合作的医院组成：华盛顿医院中心、国家康复医院、国家儿童医学中心、乔治城大学医院和霍华德大学医院。NINDS的校内中风项目也是附属项目。随着乔治华盛顿大学医院在第三年的加入，我们将捕获几乎所有的DC中风患者。2012年，扫描站点评估了2100多例急性中风。我们国家卫生研究院资助的试验招募非常出色；我们曾经或现在是MR RESCUE， MR WITNESS， ICARE， SITT和IPSS的前5位站点。SCANR为试验网络提供以下专业知识：急性多模态MRI，神经康复，小儿中风和差异。特别重要的是我们在招募城市服务不足的中风患者进行研究方面的经验；我们现有的参与者招募和保留核心（PRRO Core）可以成为其他网站的典范。我们有一种不同寻常的能力来招募一个完全代表我们社区的样本。SCANR的科学基础包括两所卡内基研究大学和两个CTSA项目。我们的临床前专业知识包括多模态成像、生物标志物、脑刺激、机器人、神经康复试验、适应性试验设计和差异研究。我们完全有能力将早期的NINDS校内研究转化为校外环境。我们有一个III期和两个II期神经康复试验提案处于不同的发展阶段。SCANR将为中风临床研究员提供优秀的研究培训和指导，为他们从事富有成效的中风研究工作做好准备。目前有5个直接相关的奖学金项目和2个成人神经病学住院医师。本次培训结合了脑卒中领域强大的多学科临床和研究专业知识以及临床科学家在研究培训和职业发展方面的丰富经验。

DESCRIPTION (provided by applicant): SCANR, the Stroke National Capital Area Network for Research is based in Washington, DC. SCANR is composed of 5 hospitals that already collaborate on stroke research: Washington Hospital Center, National Rehabilitation Hospital, Children's National Medical Center, Georgetown University Hospital, and Howard University Hospital. The NINDS Intramural Stroke Program is also affiliated. With the addition of George Washington University Hospital in Year 3, we will capture nearly all DC stroke patients. SCANR sites evaluated over 2100 acute strokes in 2012. Our NINDS-funded trial recruitment is excellent; we were or are in the top 5 sites for MR RESCUE, MR WITNESS, ICARE, SITT, and the IPSS. SCANR offers the Trial Network expertise in the following: acute multimodal MRI, neurorehab, pediatric stroke, and disparities. Of particular significance is our experience with recruiting urban underserved stroke patients into studies; our existing Participant Recruitment and Retention Core (PRRO Core) can be a model for other sites. We have an unusual ability to recruit a sample fully representative of our community. SCANR's scientific base includes two Carnegie Research Universities and two CTSA programs. Our preclinical expertise includes multimodal imaging, biomarkers, brain stimulation, robotics, neurorehabilitation trials, adaptive trial design, and disparities research. We are well positioned to translate early phase NINDS intramural studies into the extramural setting. We have a Phase III and two Phase II neurorehabilitation trials proposals in varying stages of development. SCANR will provide outstanding research training and mentorship for stroke clinician fellows, preparing them for productive stroke research careers. There are currently 5 directly relevant fellowship programs and two adult neurology residencies. This training joins strong multidisciplinary clinical and research expertise in stroke with much experience in research training and career development of clinician scientists.