Stroke National Capital Area Network for Research (SCANR)

中风国家首都地区研究网络 (Scanr)

• 批准号: 8662832
• 负责人: Alexander W Dromerick
• 金额: $ 39.16万
• 依托单位: MEDSTAR HEALTH RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-30 至 2018-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8662832
• 关键词: Acute; Adult; Area; Biological Markers; Brain; Capital; Childhood stroke; Clinical Research; Clinical Trials Design; Communities; Development; District of Columbia; Extramural Activities; Fellowship Program; Funding; Hospitals; Individual; Intervention; Magnetic Resonance Imaging; Medical center; Mentorship; Modeling; Multimodal Imaging; National Institute of Neurological Disorders and Stroke; Neurology; Neurorehabilitation; Participant; Patients; Pediatric Hospitals; Phase; Positioning Attribute; Recruitment Activity; Rehabilitation therapy; Research; Research Training; Residencies; Robotics; Sampling; Scientist; Site; Staging; Stroke; Training; Translating; Universities; University Hospitals; Washington; acute stroke; base; career; career development; experience; multidisciplinary; pre-clinical; programs; public health relevance

DESCRIPTION (provided by applicant): SCANR, the Stroke National Capital Area Network for Research is based in Washington, DC. SCANR is composed of 5 hospitals that already collaborate on stroke research: Washington Hospital Center, National Rehabilitation Hospital, Children's National Medical Center, Georgetown University Hospital, and Howard University Hospital. The NINDS Intramural Stroke Program is also affiliated. With the addition of George Washington University Hospital in Year 3, we will capture nearly all DC stroke patients. SCANR sites evaluated over 2100 acute strokes in 2012. Our NINDS-funded trial recruitment is excellent; we were or are in the top 5 sites for MR RESCUE, MR WITNESS, ICARE, SITT, and the IPSS. SCANR offers the Trial Network expertise in the following: acute multimodal MRI, neurorehab, pediatric stroke, and disparities. Of particular significance is our experience with recruiting urban underserved stroke patients into studies; our existing Participant Recruitment and Retention Core (PRRO Core) can be a model for other sites. We have an unusual ability to recruit a sample fully representative of our community. SCANR's scientific base includes two Carnegie Research Universities and two CTSA programs. Our preclinical expertise includes multimodal imaging, biomarkers, brain stimulation, robotics, neurorehabilitation trials, adaptive trial design, and disparities research. We are well positioned to translate early phase NINDS intramural studies into the extramural setting. We have a Phase III and two Phase II neurorehabilitation trials proposals in varying stages of development. SCANR will provide outstanding research training and mentorship for stroke clinician fellows, preparing them for productive stroke research careers. There are currently 5 directly relevant fellowship programs and two adult neurology residencies. This training joins strong multidisciplinary clinical and research expertise in stroke with much experience in research training and career development of clinician scientists.

描述（由申请人提供）：SCANR，卒中国家首都地区研究网络，总部设在华盛顿。SCANR由已经在中风研究方面合作的5家医院组成：华盛顿医院中心、国家康复医院、儿童国家医疗中心、乔治敦大学医院和霍华德大学医院。NINDS校内中风项目也是附属项目。随着乔治华盛顿大学医院在第三年的加入，我们将捕获几乎所有的DC中风患者。 SCANR研究中心在2012年评估了超过2100例急性卒中。我们的NINDS资助的试验招募非常出色;我们曾经或现在是MR RESCUE、MR WITNESS、ICARE、SITT和IPSS的前5名研究中心。 SCANR在以下方面提供试验网络专业知识：急性多模式MRI，神经康复，儿科中风和差异。特别重要的是我们招募城市服务不足的卒中患者参与研究的经验;我们现有的参与者招募和保留核心（PRRO核心）可以成为其他研究中心的模型。我们有一种不同寻常的能力，可以招募一个完全代表我们社区的样本。 SCANR的科学基础包括两所卡内基研究型大学和两个CTSA项目。我们的临床前专业知识包括多模式成像，生物标志物，脑刺激，机器人，神经康复试验，适应性试验设计和差异研究。我们有能力将早期的NINDS内部研究转化为外部环境。我们有一个III期和两个II期神经康复试验提案，处于不同的发展阶段。 SCANR将为中风临床医生研究员提供出色的研究培训和指导，为他们从事富有成效的中风研究事业做好准备。目前有5个直接相关的奖学金计划和两个成人神经病学住院医师。这种培训结合了强大的多学科临床和研究专业知识，在中风的研究培训和临床医生科学家的职业发展方面有很多经验。