Relating laboratory measures of UE prosthesis performance to use in everyday life

描述(由申请人提供)： 研究建议：将UE假体性能的实验室测量与日常生活中的使用相关联：一项先导性研究。首席研究员：亚历山大·W·德罗梅里克医学博士摘要我们的长期目标是通过改善上肢截肢(UE)退伍军人和平民的治疗来改善他们的生活。在这个试点方案中，我们通过系统地评估假肢在日常生活中的使用情况，朝着这个目标前进。我们将使用客观和自我报告的测量方法，并将这些现实世界的测量方法与常用的和基于实验室的实验测量方法联系起来。这项工作将提供有关假肢日常使用的试点数据，以及它们如何与常用的实验室技能测量相关联。它还将客观地评估改进假体设计和训练的两个有希望的目标(躯干和残肢的代偿动作；握力控制)是否与现实世界的使用有关。如果是这样的话，这些可能成为未来假肢设计和训练方案的目标。这些试点数据将提供对这些重要领域的即时初步洞察，并将形成更大规模权威性研究的基础。我们的目标：具体目标1：检查日常假体使用(手臂运动和终端设备激活)的主观报告和客观指标之间的关系。这些数据将被用来估计效应大小，以便随后进行更大规模的确定性研究。具体目标2：检查实验室测量的粗大和精细运动能力、躯干代偿和握力运动控制与日常假体使用的主观和客观测量之间的关系。

DESCRIPTION (provided by applicant): Research Proposal: Relating laboratory measures of UE prosthesis performance to use in everyday life: A Pilot Study. Principal Investigator: Alexander W. Dromerick, MD Abstract Our long term objective is to improve the lives of veterans and civilians with upper extremity (UE) amputation by improving the treatments they receive. In this pilot proposal, we advance towards this goal by systematically evaluating use of prosthetic limbs in everyday life. We will use objective and self-report measures, and relate these real world measures to both commonly used and experimental laboratory-based measures. This work will provide pilot data about everyday use of prosthetic limbs and how they relate to commonly used laboratory measures of skill. It will also objectively evaluate whether two promising targets for improving prosthesis design and training (compensatory maneuvers of the trunk and residual limb; grip force control) are related to real-world use. If so, these could be targets for future prosthetic limb designs and training protocols. This pilot data will provide immediate preliminary insight into these important areas, and will form the basis for larger-scale definitive studies. Our Aims: Specific Aim 1: Examine the relationship between subjective reports and objective indicators of everyday prosthesis use (arm motion and terminal device activation). These data will be used to estimate effect size for a subsequent larger scale definitive study. Specific Aim 2: Examine the relationship between laboratory measures of gross and fine motor performance, trunk compensation, and grip motor control with subjective and objective measures of everyday prosthesis use.