SUNY DOWNSTATE "R TRAIN": NEUROLOGY RESEARCH EDUCATION PROGRAM

描述（由申请人提供）：随着新的研究领域和治疗进展，基础、转化和临床神经科学知识的爆炸式增长，我们同时经历了临床科学家（K资助）向NINDS提出的竞争性申请数量的减少，特别是少数族裔（URM）申请人数量非常少。因此，我们必须系统地在下一代的职业生涯中尽早开始，将住院医师/临床研究员培训与正式的研究经验和工具结合起来。这是必要的，以激励我们的学员发展和保持“肚子里的火”，以正确地进行和领导持续的，资助的神经系统疾病的机制，病因和治疗研究。我们的R25申请来自纽约州立大学（SUNY）下州医学中心的神经科学研究教育项目，名为“神经科学研究活动住院医师培训”（SUNY“R TRAIN”），旨在正式培养纽约州立大学下州医学院的神经病学医师神经科学家。该项目提供研究和教育经验，为包括urm在内的受训者做好准备，使他们能够成功竞争个人奖学金/指导职业发展奖，从而促进独立的研究事业。具体来说，我们建议：每年招募一名神经内科住院医师，该住院医师必须清楚地表明其研究能力和愿望，并将从正式的研究指导中受益。主要目标包括：(1)让住院医师沉浸在一个研究密集、有指导的环境中，专注于将她/他培养成一名医师研究员，为候选人成功竞争K08或K23奖项做好准备；(2)进一步发展、完善和采用一套正式的神经内科住院医师/临床神经科学研究研究员第一年的研究培训课程。该项目，即纽约州立大学R TRAIN，将利用纽约州立大学下州分校已建立的项目和机构资源，为每位受训者创建一个合作指导团队（主要导师和合作教师），通过利用来自不同部门的额外现有研究共同指导机会，增强受训者在纽约州立大学R TRAIN项目中的多学科研究环境，并持续评估纽约州立大学R TRAIN项目。将有16位主要导师，他们有指导和资助的综合记录。鉴于我们的住院医师中几乎有一半是注册护士，我们计划填补培训注册护士成为神经病学研究的临床科学家的关键需求。

DESCRIPTION (provided by applicant): As basic, translational, and clinical neuroscience explodes in knowledge with new areas of research and treatment advances, we are simultaneously experiencing a reduction in the number of competitive applications to NINDS by clinician-scientists (K grants), and in particular, very low numbers of underrepresented minority (URM) applicants. We therefore must systematically begin earlier in the next generation's careers to meld residency/clinical fellowship training with formal research experiences and tools. This is necessary to invigorate our trainees to develop and maintain the "fire in their belly" to properly conduct and lead sustained, funded research on mechanisms, etiologies, and treatments of neurological diseases. Our R25 application from The Neuroscience Research Education Program at The State University of New York (SUNY) Downstate Medical Center called The "Resident Training In Research Activities In Neuroscience (SUNY "R TRAIN") is designed to formally develop physician neuroscientists in Neurology at SUNY Downstate College of Medicine. This program provides research and educational experiences that prepare the trainees, including URMs, to successfully compete for individual fellowships/mentored career development awards that should facilitate independent research careers. Specifically we propose to: Recruit one neurology resident each year who clearly demonstrates both ability and desire for research and who would benefit from formal research mentoring. The major goals include: (1) immerse the resident in a research intensive, mentored milieu focused on developing her/him into a physician researcher to prepare the candidates to compete successfully for K08 or K23 awards and (2) further develop, refine, and employ a formalized research training curriculum for the neurology residency/first year of clinical neuroscience research fellows. This program, The SUNY R TRAIN, will utilize established programs and institutional resources at SUNY Downstate to create a collaborative mentoring team (Primary Mentor and Collaborating Faculty) for each trainee, enhance the trainees' multi-disciplinary research milieu within the SUNY R TRAIN program by employing additional existing research co-mentorship opportunities from various departments, and evaluate the SUNY R TRAIN program on an ongoing basis. There will be sixteen primary mentors with a combined mentoring and funding track record. Given almost half of our residents are URMs, we project filling a critical need of training URMs as clinician-scientists in neurology research.