SUNY DOWNSTATE "R TRAIN": NEUROLOGY RESEARCH EDUCATION PROGRAM

描述(由申请人提供)：随着基础、翻译和临床神经科学知识随着研究和治疗新领域的进步而爆炸式增长，我们同时面临着临床医生-科学家对NINDS的竞争性申请(K补助金)的数量减少，特别是代表不足的少数族裔(URM)申请者的数量非常少。因此，我们必须在下一代职业生涯的早期系统地开始，将住院医师/临床研究员培训与正式的研究经验和工具结合起来。这是必要的，以激励我们的受训者发展和保持“腹中之火”，适当地开展和领导关于神经系统疾病的机制、病因和治疗的持续的、受资助的研究。我们从纽约州立大学(SUNY)下州医学中心的神经科学研究教育计划申请的R25名为“神经科学研究活动住院医师培训”(SUNY“R TRAIN”)，旨在正式培养纽约州立大学下州医学院的神经学内科神经学家。该计划提供研究和教育经验，为学员(包括URM)成功竞争个人奖学金/指导职业发展奖做好准备，这些奖项应该有助于独立研究职业生涯。具体地说，我们建议：每年招聘一名神经学住院医生，他必须清楚地表明自己的研究能力和愿望，并将从正式的研究指导中受益。主要目标包括：(1)让住院医生沉浸在一个密集的、有指导的环境中，专注于将她/他培养成一名内科研究员，为候选人成功竞争K08或K23奖项做好准备；以及(2)为神经学住院医师/临床神经科学研究员的第一年进一步开发、完善和采用正式的研究培训课程。这一项目，即纽约州立大学R培训项目，将利用纽约州立大学北部现有的项目和机构资源，为每个学员创建一个协作指导团队(主要导师和协作教师)，通过从不同部门聘用更多现有的研究共同指导机会，增强学员在纽约州立大学R培训项目中的多学科研究环境，并对纽约州立大学R培训项目进行持续评估。将有16名主要导师，他们的指导和资助记录相结合。鉴于我们几乎一半的住院医生是URM，我们计划满足将URM培训为神经学研究临床医生科学家的迫切需求。

DESCRIPTION (provided by applicant): As basic, translational, and clinical neuroscience explodes in knowledge with new areas of research and treatment advances, we are simultaneously experiencing a reduction in the number of competitive applications to NINDS by clinician-scientists (K grants), and in particular, very low numbers of underrepresented minority (URM) applicants. We therefore must systematically begin earlier in the next generation's careers to meld residency/clinical fellowship training with formal research experiences and tools. This is necessary to invigorate our trainees to develop and maintain the "fire in their belly" to properly conduct and lead sustained, funded research on mechanisms, etiologies, and treatments of neurological diseases. Our R25 application from The Neuroscience Research Education Program at The State University of New York (SUNY) Downstate Medical Center called The "Resident Training In Research Activities In Neuroscience (SUNY "R TRAIN") is designed to formally develop physician neuroscientists in Neurology at SUNY Downstate College of Medicine. This program provides research and educational experiences that prepare the trainees, including URMs, to successfully compete for individual fellowships/mentored career development awards that should facilitate independent research careers. Specifically we propose to: Recruit one neurology resident each year who clearly demonstrates both ability and desire for research and who would benefit from formal research mentoring. The major goals include: (1) immerse the resident in a research intensive, mentored milieu focused on developing her/him into a physician researcher to prepare the candidates to compete successfully for K08 or K23 awards and (2) further develop, refine, and employ a formalized research training curriculum for the neurology residency/first year of clinical neuroscience research fellows. This program, The SUNY R TRAIN, will utilize established programs and institutional resources at SUNY Downstate to create a collaborative mentoring team (Primary Mentor and Collaborating Faculty) for each trainee, enhance the trainees' multi-disciplinary research milieu within the SUNY R TRAIN program by employing additional existing research co-mentorship opportunities from various departments, and evaluate the SUNY R TRAIN program on an ongoing basis. There will be sixteen primary mentors with a combined mentoring and funding track record. Given almost half of our residents are URMs, we project filling a critical need of training URMs as clinician-scientists in neurology research.