SUNY DOWNSTATE "R TRAIN": NEUROLOGY RESEARCH EDUCATION PROGRAM

描述（由申请人提供）：随着基础、转化和临床神经科学知识的爆炸，以及新的研究和治疗领域的进步，我们同时经历了临床科学家（K赠款）对NINDS的竞争性申请数量的减少，特别是代表性不足的少数民族（URM）申请人的数量非常少。因此，我们必须在下一代的职业生涯中系统地开始，将住院医师/临床研究员培训与正式的研究经验和工具相结合。这对于激励我们的学员发展和保持“肚子里的火”是必要的，以正确地进行和领导关于神经系统疾病的机制，病因和治疗的持续，资助的研究。我们的R25申请来自州立大学纽约（SUNY）Downstate医学中心的神经科学研究教育计划，称为“神经科学研究活动的住院医师培训”（SUNY“R TRAIN”），旨在正式培养SUNY Downstate医学院神经病学的医生神经科学家。该计划提供研究和教育经验，为学员（包括URM）成功竞争个人奖学金/指导职业发展奖做好准备，这些奖学金/指导职业发展奖应促进独立研究职业。具体而言，我们建议：每年招募一名神经病学住院医师，他必须清楚地展示出研究的能力和愿望，并能从正式的研究指导中受益。主要目标包括：（1）使住院医师沉浸在研究密集型的指导环境中，重点是将她/他培养成一名医生研究员，为候选人成功竞争K 08或K23奖项做好准备，（2）进一步开发，完善和采用神经病学住院医师/临床神经科学研究员第一年的正式研究培训课程。该计划，纽约州立大学R培训，将利用既定的计划和机构资源在纽约州立大学Downstate创建一个协作辅导团队（主要导师和协作教师）为每个学员，提高学员的多学科研究环境内的纽约州立大学R培训计划，通过采用额外的现有研究共同导师的机会，从各个部门，并评估纽约州立大学R培训计划在持续的基础上。将有16名主要导师，他们具有指导和资助的综合记录。鉴于近一半的居民是URM，我们项目填补了培训URM作为神经病学研究的临床科学家的迫切需求。

DESCRIPTION (provided by applicant): As basic, translational, and clinical neuroscience explodes in knowledge with new areas of research and treatment advances, we are simultaneously experiencing a reduction in the number of competitive applications to NINDS by clinician-scientists (K grants), and in particular, very low numbers of underrepresented minority (URM) applicants. We therefore must systematically begin earlier in the next generation's careers to meld residency/clinical fellowship training with formal research experiences and tools. This is necessary to invigorate our trainees to develop and maintain the "fire in their belly" to properly conduct and lead sustained, funded research on mechanisms, etiologies, and treatments of neurological diseases. Our R25 application from The Neuroscience Research Education Program at The State University of New York (SUNY) Downstate Medical Center called The "Resident Training In Research Activities In Neuroscience (SUNY "R TRAIN") is designed to formally develop physician neuroscientists in Neurology at SUNY Downstate College of Medicine. This program provides research and educational experiences that prepare the trainees, including URMs, to successfully compete for individual fellowships/mentored career development awards that should facilitate independent research careers. Specifically we propose to: Recruit one neurology resident each year who clearly demonstrates both ability and desire for research and who would benefit from formal research mentoring. The major goals include: (1) immerse the resident in a research intensive, mentored milieu focused on developing her/him into a physician researcher to prepare the candidates to compete successfully for K08 or K23 awards and (2) further develop, refine, and employ a formalized research training curriculum for the neurology residency/first year of clinical neuroscience research fellows. This program, The SUNY R TRAIN, will utilize established programs and institutional resources at SUNY Downstate to create a collaborative mentoring team (Primary Mentor and Collaborating Faculty) for each trainee, enhance the trainees' multi-disciplinary research milieu within the SUNY R TRAIN program by employing additional existing research co-mentorship opportunities from various departments, and evaluate the SUNY R TRAIN program on an ongoing basis. There will be sixteen primary mentors with a combined mentoring and funding track record. Given almost half of our residents are URMs, we project filling a critical need of training URMs as clinician-scientists in neurology research.