Texas Center for Minority Health, Education, Research and Outreach

描述(由申请人提供)：尽管美国人的健康状况在过去20年中得到了全面改善，但基于种族和民族、性别、教育水平和收入以及其他社会特征，健康结果仍然存在显著差异。美国社会的许多阶层越来越意识到，持续的健康差距是不可接受的，通过协调和有针对性的行动，大多数健康差距是可以纠正的。得克萨斯健康差异中心(TCHD)成立于2005年，作为一个出口中心，在过去的六年里，该中心在其当地社区、整个德克萨斯州和全国许多地区的健康差异研究、教育和推广方面一直处于领先地位。在其丰富的经验和广泛的关系的基础上，TCHD及其伙伴机构建议建立NIMHD英才中心(COE)，重点关注妇女的健康差距。与TCHD以社区为基础的参与性研究(CBPR)的重点一致，通过与当地和国家合作伙伴的大量社区对话，确定了对妇女健康的重点。拟议的COE将专注于通过采用翻译和CBPR方法来确定HIV-1进展的新生物标记物，开发针对三阴性乳腺癌的检测和治疗策略，以及解决体重减轻和肥胖问题，从而减少健康差距。我们的COE将扩大和加强TCHD进行基础、临床、翻译、参与性和社会行为研究的现有基础设施和能力。我们对妇女健康差距的关注将解决美国、德克萨斯州和我们当地社区中种族和少数民族妇女的重大需求。我们还将扩大和发展新的教育和社区外展活动，与我们的合作伙伴代表不足的少数族裔机构和社区。我们医疗保健中心的目标是：1)培养现有的关系，并与医疗保健机构发展新的关系；2)针对艾滋病毒预防、乳腺癌和减少肥胖的问题，就妇女的健康差距开展有影响力的研究；3)为医疗保健机构的学生和教职员工提供独特的培训和指导机会，进行健康差距研究；4)教育保健专业实习生、保健从业者和政策制定者，使他们了解解决持续存在的健康差距的存在和需要；以及5)通过传播健康信息、促进参与健康教育和研究以及开展疾病预防活动，成为少数族裔社区的可靠资源。

DESCRIPTION (provided by applicant): Despite the overall improvement in the health of Americans during the past two decades, significant disparities in health outcomes persist based on race and ethnicity, sex, level of education and income, and other social characteristics. There is a growing awareness in many segments of United States society that persistent health disparities are not acceptable, and that through, coordinated and targeted actions most health disparities are correctable. Created in 2005 with partial funding as an EXPORT Center, for the past six years the Texas Center for Health Disparities (TCHD) has been a leader in health disparities research, education, and outreach In its local community, throughout the State of Texas, and in many parts of the nation. Building on its significant experience and expansive relationships, the TCHD and its partner institutions propose the development of an NIMHD Center of Excellence (COE) with a focus on Women's Health Disparities. Consistent with the community-based participatory research (CBPR) focus of the TCHD, the focus on women's health was identified through substantial community dialogue with local and national partners. The proposed COE will focus on reducing health disparities by employing translational and CBPR approaches for identifying novel biomarkers for HIV-1 progression, developing detection and therapeutic strategies for triple negative breast cancer, and addressing weight loss and obesity. Our COE will augment and strengthen the existing infrastructure and capacity of the TCHD for conducting basic, clinical, translational, participatory, and socio-behavioral research. Our focus on Women's Health Disparities will address a significant need among racial and ethnic minority women in the U.S., the State of Texas, and our local community. We will also expand and develop new education and community outreach activities with our partner underrepresented minority (URM) institutions and community. The objectives of our COE are to: 1) Foster existing relationships and develop new relationships with URM institutions; 2) Conduct impactful research on Women's Health Disparities addressing HIV prevention, breast cancer, and obesity reduction; 3) Provide unique training and mentoring opportunities for URM students and faculty from URM institutions in health disparity research; 4. Educate health professions trainees, health care practitioners and policy makers on the existence and need to address persistent health disparities; and, 5) Serve as a reliable resource for minority communities by disseminating health information, promoting participation in health education and research, and implementing disease prevention activities.