Texas Center for Minority Health, Education, Research and Outreach

描述（由申请人提供）：尽管在过去的二十年中，美国人的健康状况得到了全面改善，但基于种族和民族、性别、教育和收入水平以及其他社会特征，健康结果的显著差异仍然存在。美国社会的许多阶层日益认识到，健康方面的持续差距是不可接受的，通过协调一致和有针对性的行动，大多数健康差距是可以纠正的。成立于2005年，部分资金作为出口中心，在过去的六年中，得克萨斯州健康差异中心（TCHD）一直是健康差异研究，教育和推广的领导者，在当地社区，整个得克萨斯州，并在全国许多地区。TCHD及其伙伴机构基于其丰富的经验和广泛的关系，提议建立一个NIMHD卓越中心（COE），重点关注妇女的健康差异。与TCHD以社区为基础的参与性研究（CBPR）的重点一致，通过与地方和国家合作伙伴的大量社区对话，确定了对妇女健康的关注。拟议的COE将侧重于通过采用翻译和CBPR方法来确定HIV-1进展的新生物标志物，开发三阴性乳腺癌的检测和治疗策略，以及解决体重减轻和肥胖问题，从而减少健康差异。我们的COE将扩大和加强TCHD现有的基础设施和能力，以进行基础，临床，转化，参与和社会行为研究。我们对妇女健康差异的关注将解决美国种族和少数民族妇女的重大需求，德克萨斯州和我们当地的社区我们还将扩大和发展新的教育和社区外展活动与我们的合作伙伴代表性不足的少数民族（URM）机构和社区。我们的COE的目标是：1）促进现有的关系，并与URM机构发展新的关系; 2）对妇女的健康差异进行有效的研究，解决艾滋病毒预防，乳腺癌和肥胖减少; 3）为URM的学生和教师提供独特的培训和指导机会从URM机构在健康差异研究; 4。教育卫生专业受训人员、卫生保健从业人员和决策者，使他们认识到存在着长期存在的健康差距，并认识到解决这种差距的必要性; 5）通过传播健康信息、促进参与健康教育和研究以及开展疾病预防活动，为少数群体社区提供可靠的资源。

DESCRIPTION (provided by applicant): Despite the overall improvement in the health of Americans during the past two decades, significant disparities in health outcomes persist based on race and ethnicity, sex, level of education and income, and other social characteristics. There is a growing awareness in many segments of United States society that persistent health disparities are not acceptable, and that through, coordinated and targeted actions most health disparities are correctable. Created in 2005 with partial funding as an EXPORT Center, for the past six years the Texas Center for Health Disparities (TCHD) has been a leader in health disparities research, education, and outreach In its local community, throughout the State of Texas, and in many parts of the nation. Building on its significant experience and expansive relationships, the TCHD and its partner institutions propose the development of an NIMHD Center of Excellence (COE) with a focus on Women's Health Disparities. Consistent with the community-based participatory research (CBPR) focus of the TCHD, the focus on women's health was identified through substantial community dialogue with local and national partners. The proposed COE will focus on reducing health disparities by employing translational and CBPR approaches for identifying novel biomarkers for HIV-1 progression, developing detection and therapeutic strategies for triple negative breast cancer, and addressing weight loss and obesity. Our COE will augment and strengthen the existing infrastructure and capacity of the TCHD for conducting basic, clinical, translational, participatory, and socio-behavioral research. Our focus on Women's Health Disparities will address a significant need among racial and ethnic minority women in the U.S., the State of Texas, and our local community. We will also expand and develop new education and community outreach activities with our partner underrepresented minority (URM) institutions and community. The objectives of our COE are to: 1) Foster existing relationships and develop new relationships with URM institutions; 2) Conduct impactful research on Women's Health Disparities addressing HIV prevention, breast cancer, and obesity reduction; 3) Provide unique training and mentoring opportunities for URM students and faculty from URM institutions in health disparity research; 4. Educate health professions trainees, health care practitioners and policy makers on the existence and need to address persistent health disparities; and, 5) Serve as a reliable resource for minority communities by disseminating health information, promoting participation in health education and research, and implementing disease prevention activities.