Mechanics of Hearing Workshop

听觉力学工作坊

• 批准号: 8598161
• 负责人: Kiriaki Domenica Karavitaki
• 金额: $ 4万
• 依托单位: HARVARD MEDICAL SCHOOL
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-07-01 至 2016-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8598161
• 关键词: Affect; Area; Auditory; Auditory system; Biological; Biomechanics; Biophysics; Cochlea; Communities; Complex; Computers; Country; Data; Educational workshop; Engineering; Etiology; Experimental Models; Frequencies; Funding; Germany; Goals; Greece; Hair Cells; Health; Hearing; Human; Impairment; Individual; Institution; International; Japan; Knowledge; Learning; Location; Massachusetts; Measurement; Mechanics; Modeling; Molecular; Molecular Biology; Motion; Mutation; Netherlands; Neurosciences; Optical Tomography; Organ of Corti; Outer Hair Cells; Participant; Peripheral; Physiological; Physiology; Postdoctoral Fellow; Production; Property; Proteins; Publications; Request for Proposals; Research; Research Personnel; Scholarship; Sensory; Societies; Structure; Students; System; Talents; Techniques; Travel; United Kingdom; United States; United States National Institutes of Health; Visual; Work; World Health Organization; base; cell motility; cellular transduction; college; cost; deafness; doctoral student; hearing impairment; in vivo; mathematical model; mechanical behavior; medical schools; molecular dynamics; molecular mechanics; new technology; public health relevance; symposium; tectorial membrane

DESCRIPTION (provided by applicant): We are requesting partial support to cover the expenses of the 12th Mechanics of Hearing Workshop to be held in Attica, Greece in 2014. Since their inception in 1983, the Mechanics of Hearing Workshops have provided the primary forum for presenting, debating, and sparking advances in the fields of auditory biomechanics and biophysics. Convened at three-year intervals, Workshops bring together for a week of intense discussion researchers working on the mechanics of hearing at the molecular, cellular and systems levels using biological, mathematical, and engineering techniques. Attendees are from a wide range of U.S. and international institutions, and the Workshop has historically been held in both domestic and international locations. The previous Workshop was held at Williams College in Massachusetts; it attracted 162 participants from 20 countries and five continents. Previous Workshops were held in the Netherlands, United Kingdom, Japan, Germany and United States. The 2014 Workshop is organized by Harvard Medical School and will be held near Athens, Greece. Greece was chosen as a central location that allows easy travel for the majority of the participants. This, the 12th Workshop, aims to (i) synthesize new results in this rapidly progressing, multi-disciplinary research area; (ii) establish new research goals and collaborative projects; (iii) attract new talent to the field; and (iv) disseminate knowledge to th broader community. For graduate and post-doctoral students, the Workshops offer an invaluable opportunity to discuss their work, develop new ideas, and talk with established investigators. The Workshop will focus on the biomechanics, biophysics, and cellular/molecular physiology of the peripheral auditory system. Contributions related to the mechanics of non-mammalian auditory and vestibular systems, as well as other biological mechano-transducing systems, will also be encouraged. A key addition to the 2014 MoH will be topics in molecular mechanics: the atomic structures and mechanical properties of single proteins in the mechanotransduction and electromotility complexes, how these act in the overall context of the intact cochlea, and how mutations that affect mechanics may cause hearing loss. A goal will be to integrate mechanics from the level of single proteins to cochlear macro-mechanics. In this proposal, we request funds from the NIH to cover student and post doctoral scholarships and travel, and a portion of audio-visual and publication costs.

描述（由申请人提供）：我们要求部分支持，以支付2014年在希腊阿提卡举行的第12届听力研讨会的费用。自1983年成立以来，听力研讨会的机制为展示，辩论和在听觉生物力学和生物学领域的影响提供了主要论坛。研讨会以三年的间隔召集，将使用生物学，数学和工程技术在分子，细胞和系统水平上从事听力机制进行一周的激烈讨论研究人员。与会者来自美国和国际机构各个机构，该研讨会历史上一直在国内和国际地点举行。以前的研讨会在马萨诸塞州的威廉姆斯学院举行；它吸引了来自20个国家和五大洲的162名参与者。以前的讲习班在荷兰，英国，日本，德国和美国举行。 2014年的研讨会由哈佛医学院组织，将在希腊雅典附近举行。希腊被选为中心位置，可轻松地为大多数参与者出行。这是第12届研讨会，目的是（i）在这个迅速发展的多学科研究领域中综合新的结果； （ii）建立新的研究目标和协作项目； （iii）吸引新的人才进入该领域； （iv）将知识传播给更广泛的社区。对于研究生和博士后学生，研讨会为讨论他们的工作，发展新想法并与既定的调查人员进行了交谈提供了宝贵的机会。该研讨会将重点放在外围听觉系统的生物力学，生物物理学和细胞/分子生理学上。还将鼓励与非哺乳动物听觉和前庭系统以及其他生物机械转化系统的力学有关的贡献。 2014年MOH的一个关键将是分子力学中的主题：单蛋白在机械传输和电动元中的原子结构和力学性质，这些蛋白质在完整的耳蜗的整体背景下如何起作用，以及影响力学的突变如何引起听力损失。一个目标是将机械师从单蛋白的水平集成到耳蜗宏观力学。在此提案中，我们要求NIH的资金涵盖学生，并在博士后奖学金和旅行，以及一部分视听和出版成本。