Pilot Project

项目摘要：参与临床和预防研究的某些亚群人数少得不成比例，对科学成果的代表性产生重大影响，并导致社会和临床不公正。(1)在美国和纽约西部，拉丁美洲人是增长最快的人口群体之一，他们认为参加癌症筛查和自愿参加生物医学研究的风险同样高，这与黑人如出一辙。（二） 该提案将调查使布法罗的拉丁美洲人与罗斯韦尔公园癌症研究所的科学家接触的策略，以增加彼此之间的相互了解和参与癌症预防研究的生物标本捐赠，从而获得有关捐赠生物标本类型变化的试点数据（即，唾液和/或血液）。我们将在现有的合作伙伴关系的基础上，与500多名拉丁裔妇女和男子谁参加了社区为基础的乳腺癌和宫颈癌预防教育计划（研究标题：埃斯佩兰萨和维达），以解决以下具体目标：1）调查 来自布法罗拉丁裔社区代表的看法、知识和信念，以确定这些看法可能如何影响以帕塔银行和生物储存库（PBBR）为重点的研究参与，2）Pevelop是一项试点社区友好干预措施，旨在增强拉丁裔居民对研究的知识、理解、意图和参与，重点是参与PBBR，3）调查教育和招募拉丁妇女及其家庭生物标本的可行性和有效性 通过社区为基础的方法和干预措施，在Esperanza y维达研究队列中进行研究捐赠，通过出勤率，调查和研究参与来衡量。从tiiis研究的结果预计将确定具体的障碍，挑战和资产，研究参与与我们当地的拉丁裔社区; 以及研究机构和社区合作伙伴招募、积累和分析与癌症研究相关的措施所需的技术设施。这可以导致具体的可检验的研究假设，未来的环境流行病学CBPR研究的潜力，并提供指导方针和基础，为拉丁美洲社区的能力建设周围的研究项目。

Project Summary: The disproportionately lower number of certain subpopulations participating in clinical and prevention research has a significant impact on the representativeness of scientific outcomes and result in social and clinical injustices.(1) Latinos are one of the fastest growing population groups in the United States and in Western New York and mirror blacks in their perception of equally high levels of risk for participating in cancer screening examinations and for volunteering to become research participants in biomedical studies.(2) This proposal will investigate strategies to engage Latinos in Buffalo with scientists at Roswell Park Cancer Institute to increase mutual understanding of each other and participation in biospecimen donation for cancer prevention research, thereby, obtaining pilot data on variations in the types of biospecimens donated (i.e., saliva and/or blood). We will build on our existing partnership with a cohort of more than 500 Latina women and men who participated in a community-based breast and cervical cancer educational prevention inten/ention program (Study Title: Esperanza y Vida) to address the following specific aims: 1) Investigate the perceptions, knowledge and beliefs of representatives from the Latino community in Buffalo to determine how these perceptions are likely to impact participation in research using the Pata Bank & BioRepository (PBBR) as a focus, 2) Pevelop a pilot community-friendly intervention to enhance knowledge, understanding, intent, and participation in research by Latino residents that focuses on participation in the PBBR, 3) Investigate the feasibility and effectiveness of educating and recruiting Latina women and their families to biospecimen donation for research through community-based methods and interventions within the Esperanza y Vida study cohort as measured through attendance, surveys and study participation. Results from tiiis study are expected to identify specific barriers, challenges, and assets to research participation with our local Latino communities; and the technical accommodations necessary for a research institution and community partners to recruit, accrue, and analyze measures related to cancer research. This can lead to specific testable research hypotheses, potential for future environmental epidemiological CBPR studies, and provide guidelines and a foundation for building Latino community capacity around research projects.