Building a Multidisciplinary Research Program to Address Hypertension Disparities:Exploring the Neurocognitive Mechanisms of a Self-Management Intervention for African American Women with Hypertension

建立一个多学科研究计划来解决高血压差异:探索非裔美国高血压女性自我管理干预的神经认知机制

基本信息

  • 批准号:
    10334538
  • 负责人:
  • 金额:
    $ 14.94万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2019
  • 资助国家:
    美国
  • 起止时间:
    2019-02-01 至 2024-01-31
  • 项目状态:
    已结题

项目摘要

PROJECT ABSTRACT With a continued increased in the diagnosis and prevalence of hypertension among African American women, this group is particularly vulnerable to stroke, end-stage renal disease, and premature death. Although there are interventions available to help patients manage chronic disease, there is significant variability in blood pressure control among African American women. Current approaches to aid patients in making lifestyle changes have primarily been “one size fits all” methods. Self-management behaviors require cognitive effort – for planning and goal-setting, these factors are associated with distinct patterns of brain activity, referred to as “neuroprocessing.” The relationship between neuroprocessing and self-management behavior is poorly understood. Findings from our pilot studies show a large correlation between health information behavior (information sharing) and activation in the default mode network (comprised of the medial parietal and prefrontal cortices, and temporo-parietal junctions and responsible for social and emotional modes of thought) and the ventromedial prefrontal cortex (shown to mediate links between social connection and health). A better understanding of how brain activity (ability to differentiate between neurological prompts) changes in response to our hypertension education programs will improve the precision and tailoring of self-management interventions. The objective of this project is to develop and pilot test a newly designed, health information behavior enhanced intervention to improve self-management of hypertension in African American women. Using functional magnetic resonance imaging, or fMRI, we will examine brain activity (default mode network vs. task positive network) in response to video prompts. We will assess the influence of the intervention on neurocognitive processes associated with self-management in a subset of the sample to explore the neurobiological mechanisms underlying the intervention. This work will contribute to the reduction of the tremendous health disparities affecting African American women. The findings will be used to support future studies examining the effects of our information sharing intervention in a larger sample of African American women with hypertension. Dr. Jones's program of research is focused on designing and testing self-management interventions to improve blood pressure control among African American women, as well as detailing the individual neuroprocessing profiles associated with successful response to such interventions. The training and mentoring plan will promote development in three areas: 1) intervention design and testing, 2) cognitive neuroscience, and 3) grantsmanship. This multidisciplinary team of experienced mentors and advisors will oversee a range of training and research activities in these areas to ensure Dr. Jones's future success. The exceptional resources of a top university and a mentoring team with proven success in developing junior faculty in these topic areas make the University of Michigan an ideal environment for Dr. Jones's project.
项目摘要

项目成果

期刊论文数量(0)
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科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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Lenette M. Jones其他文献

HF STATS 2024: Heart Failure Epidemiology and Outcomes Statistics An Updated 2024 Report from the Heart Failure Society of America
HF 统计数据 2024:心力衰竭流行病学与结果统计——来自美国心力衰竭协会的 2024 年最新报告
  • DOI:
    10.1016/j.cardfail.2024.07.001
  • 发表时间:
    2025-01-01
  • 期刊:
  • 影响因子:
    8.200
  • 作者:
    Biykem Bozkurt;Tariq Ahmad;Kevin Alexander;William L. Baker;Kelly Bosak;Khadijah Breathett;Spencer Carter;Mark H. Drazner;Shannon M. Dunlay;Gregg C. Fonarow;Stephen J. Greene;Paul Heidenreich;Jennifer E. Ho;Eileen Hsich;Nasrien E. Ibrahim;Lenette M. Jones;Sadiya S. Khan;Prateeti Khazanie;Todd Koelling;Christopher S. Lee;Boback Ziaeian
  • 通讯作者:
    Boback Ziaeian
Internet Health Information Seeking (IHIS)
互联网健康信息搜索 (IHIS)
  • DOI:
  • 发表时间:
    2014
  • 期刊:
  • 影响因子:
    1.8
  • 作者:
    Lenette M. Jones;T. Veinot;S. Pressler;J. Seng;Alecia M. McCall;D. Fernandez;P. Coleman
  • 通讯作者:
    P. Coleman
Prevalence, Correlates, and Outcomes of Co-Occurring Depression and Hypertensive Disorders of Pregnancy.
妊娠期并发抑郁症和高血压疾病的患病率、相关性和结果。
  • DOI:
    10.1089/jwh.2018.7144
  • 发表时间:
    2019
  • 期刊:
  • 影响因子:
    0
  • 作者:
    M. Mogos;Lenette M. Jones;Nadia Robinson;Antonette O Whitehead;Ronald Piscotty;Gelila K. Goba
  • 通讯作者:
    Gelila K. Goba
Designing a Cocreated Intervention with African American Older Adults for Hypertension Self-Management
与非裔美国老年人共同设计高血压自我管理干预措施
Therapeutic Lifestyle Changes to Decrease Unhealthy Eating Patterns and Improve Blood Pressure in African Americans
改变生活方式以减少非裔美国人不健康的饮食模式并改善血压
  • DOI:
  • 发表时间:
    2015
  • 期刊:
  • 影响因子:
    0
  • 作者:
    M. Scisney;E. Brough;O. Daramola;Markia Jones;Lenette M. Jones;S. Holmes
  • 通讯作者:
    S. Holmes

Lenette M. Jones的其他文献

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{{ truncateString('Lenette M. Jones', 18)}}的其他基金

Building a Multidisciplinary Research Program to Address Hypertension Disparities:Exploring the Neurocognitive Mechanisms of a Self-Management Intervention for African American Women with Hypertension
建立一个多学科研究计划来解决高血压差异:探索非裔美国高血压女性自我管理干预的神经认知机制
  • 批准号:
    10214672
  • 财政年份:
    2019
  • 资助金额:
    $ 14.94万
  • 项目类别:
Building a Multidisciplinary Research Program to Address Hypertension Disparities:Exploring the Neurocognitive Mechanisms of a Self-Management Intervention for African American Women with Hypertension
建立一个多学科研究计划来解决高血压差异:探索非裔美国高血压女性自我管理干预的神经认知机制
  • 批准号:
    10569503
  • 财政年份:
    2019
  • 资助金额:
    $ 14.94万
  • 项目类别:

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