2009 Insulin-like Growth Factors in Physiology and Disease Gordon Conference

2009 生理学和疾病中的胰岛素样生长因子戈登会议

• 批准号: 8423719
• 负责人: Peter S Rotwein
• 金额: $ 1.2万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-02-15 至 2014-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8423719
• 关键词: Address; Affect; Aging; Amino Acids; Area; Binding Proteins; Biology; Blood Vessels; Bone Regeneration; California; Cardiac; Cardiovascular system; Communities; Development; Disease; Fatty acid glycerol esters; Glucose; Goals; Health; Human Biology; Human Development; Hypertrophy; International; Malignant Neoplasms; Metabolic; Metabolism; Muscle Development; Myocardial; Natural regeneration; Participant; Pathology; Pathway interactions; Physiological; Physiology; Proteins; Regenerative Medicine; Regulation; Request for Proposals; Research; Resolution; Scientist; Series; Signal Transduction Pathway; Skeletal Muscle; Somatomedins; Text; Tissues; abstracting; age related; cancer therapy; disorder control; human disease; meetings; posters; programs; receptor binding; symposium; therapeutic target; tumor progression; tumorigenesis

Abstract This proposal requests partial support for an international meeting on Insulin-like Growth Factors in Physiology and Disease as part of the Gordon Research Conference series, and will be held in Ventura, California during March 22 - 27, 2009, with subsequent meetings in 2011 and 2013. The Broad and Long-term Goals of the conference are to increase our understanding of the fundamental mechanisms controlling the actions of these proteins in human biology and disease. The Specific Aims of this meeting will be to convene 25 speakers who will represent critical areas of insulin-like growth factor (IGF) research with a total of 135 participants for a five-day conference in a relatively isolated setting. The program will have a keynote address and eight sessions, which will address current issues in IGF biology as they pertain to aging and age-related diseases, regenerative medicine, cancer (including tumorigenesis, cancer progression, and targeted therapeutics), cardiovascular biology (including control of vascular smooth muscle development and pathology, and regulation of myocardial hypertrophy), metabolic regulation (specifically signal transduction pathways controlling intermediary metabolism), and other aspects of the expression and function of IGFs, their receptors, and binding proteins in normal physiology and human disease. In addition, four afternoon poster sessions will permit all participants to contribute to these topics. The Significance of this application is that the Gordon Research Conference on Insulin-like Growth Factors in Physiology and Disease is a critical component of regular meetings that propels research in the international IGF scientific community. The Health Relatedness of this application is that discussions at this Gordon Research Conference will define key questions that require experimental resolution in areas that affect human development and aging, regeneration and repair of bone, skeletal muscle, and other tissues, cancer therapy, cardiac and vascular development and disease, and the control of glucose, fat, and amino metabolism in normal physiology and disease.

摘要