International Conference on Nausea and Vomiting 2013

描述（由申请方提供）：恶心和呕吐是胃肠道疾病患者常见的高度厌恶性经历，导致食欲下降、生活质量下降和对药物的依从性下降，并伴有这些副作用。对恶心和呕吐的生物学和治疗的理解进展缓慢，部分原因是目前没有专门的科学会议来讨论和合作这些研究课题。目前的R13申请是一项请求，以支持将于2013年10月3日至4日在匹兹堡大学举行的关于恶心和呕吐机制的综合科学会议“恶心和呕吐国际会议2013”。这次会议将大大有助于国家消化疾病委员会的目标，以“了解有害的内脏信号导致恶心和呕吐有关的胃神经电和/或运动功能障碍和双向脑肠相互作用。“会议有四个目标：1）提供一个跨学科交流思想的论坛，以推进恶心和呕吐生物学机制的研究，2）促进年轻研究人员的互动，以展示研究结果，并与实验室和在恶心和呕吐研究领域工作的更资深的研究人员建立联系，3）提供一个论坛，让治疗恶心和呕吐患者的科学家和临床医生可以交流信息，4）概述和讨论恶心和呕吐生物学中尚未解决的主要问题，并提供最新的方法。会议将包括五个主要会议：1）个性化医学和遗传学; 2）胃轻瘫和周期性呕吐综合征; 3）前庭和胃肠道整合; 4）恶心的评估和控制;和5）细胞生物学和未来方向。演讲者将使用遗传学，电生理学，神经成像和电子患者报告方法，介绍与胃轻瘫，妊娠，周期性呕吐综合征，晕动病和药物反应（化疗，阿片类镇痛药）相关的恶心和呕吐的前沿研究。还将提供一个以年轻研究人员为主角的科学海报会议。会议记录将发表在同行评审期刊《实验大脑研究》上。与会者将主要包括科学家（神经科学，营养学和药理学），医生（胃肠病学，肿瘤学和麻醉学）和其他医疗保健提供者（护士，营养师）。重点将放在早期研究人员和学员的出席，以促进下一代研究人员。

DESCRIPTION (provided by applicant): Nausea and vomiting are common highly aversive experiences for patients with gastrointestinal disease and result in reductions of appetite, qualit of life, and adherence to medications with these side effects. Progress in understanding the biology and treatment of nausea and vomiting has been slow partly because there is currently no focused scientific meeting to discuss and collaborate on these research topics. The current R13 application is a request to support a comprehensive scientific conference on the mechanisms of nausea and vomiting, "International Conference on Nausea and Vomiting 2013," to be held at University of Pittsburgh (October 3-4, 2013). This conference will substantially contribute to the goal of the National Commission on Digestive Diseases to "understand the noxious visceral signaling causing nausea and vomiting related to gastric neuro-electrical and/or motor dysfunction and the bi-directional brain-gut interactions." There are four objectives of the conference: 1) Provide a forum for cross-disciplinary exchange of ideas to advance research on the biological mechanisms for nausea and vomiting, 2) Foster interactions for young investigators to present research findings and connect with laboratories and more senior investigators working in the field of nausea and vomiting research, 3) Offer a forum where scientists and clinicians who treat patients with nausea and vomiting can exchange information, and 4) Produce an overview and discussion of the major unresolved questions in nausea and vomiting biology and provide the latest methodology. The conference will include five primary sessions: 1) Personalized Medicine and Genetics; 2) Gastroparesis and Cyclic Vomiting Syndrome; 3) Vestibular and Gastrointestinal Integration; 4) Assessment and Control of Nausea; and 5) Cellular Biology and Future Directions. Speakers will present cutting edge research on nausea and vomiting related to gastroparesis, pregnancy, cyclic vomiting syndrome, motion sickness, and drug responses (chemotherapy, opioid analgesics) using genetic, electrophysiological, neuroimaging, and electronic patient reporting approaches. A scientific poster session featuring young investigators will also be provided. The proceedings of the conference will be published in a peer-reviewed journal: Experimental Brain Research. Conference attendees will primarily include scientists (neuroscience, nutrition, and pharmacology), physicians (gastroenterology, oncology, and anesthesiology), and other heathcare providers (nurses, nutritionists). Emphasis will be placed on attendance by early stage investigator faculty and trainees to facilitate the next generation of researchers.