Translational Research in Cancer

该癌症中心支持补助金（CCSG）的提案要求提供资金支持Kimmel癌症中心（KCC）的癌症研究活动，以通过将基础研究发现转化为预防，诊断，监测和治疗人类癌症的新策略来提高癌症患者的生存率和生活质量。Kimmel癌症中心的主要目标是发现和翻译癌症遗传学，细胞生物学，生物化学和免疫学的最新发现，并将其转化为治疗癌症的新方法。 Kimmel癌症中心由六个项目和十三个共享资源组成，以支持研究项目。每个项目的研究人员都参与了项目内和项目间的合作，并非常成功地为这些合作研究获得了同行评审的资金。KCC内的环境促进了许多合作研究和出版物，这些研究和出版物为癌症研究的重要进展做出了贡献。 KCC计划的资助总额为7830万美元。资金来自73个NCI赞助的项目，包括2个跨计划NCI计划项目赠款，总额为3440万美元。主任和他的新员工的努力，导致增加慈善大学和医院的支持。癌症研究和护理在托马斯杰斐逊大学的重要性反映在主任的临床和研究活动的机构，包括144，208平方米的权力。及兴建新设施（232，114平方呎）。包括新的乳腺中心，肿瘤中心和研究空间。这些新设施将容纳KCC研究人员的基础，临床和翻译工作。这些新的KCC设施将进一步加强Kimmel癌症中心的转化癌症研究工作。

This proposal for a Cancer Center Support Grant (CCSG) requests funding to support the cancer research activities of the Kimmel Cancer Center (KCC), in order to increase the survival and quality of life of cancer patients by translating basic research discoveries into new strategies to prevent, diagnose, monitor and cure human cancer. The major thrust of the Kimmel Cancer Center is in discovery and translation of the latest findings in the genetics, cell biology, biochemistry and immunology of cancer into novel modalities to cure cancer. The Kimmel Cancer Center consists of six programs and thirteen shared resources to support the research programs. Investigators in each program are involved in intra-programmatic and interprogrammatic collaborations and have been extremely successful in obtaining peer-reviewed funding for these collaborative studies. The environment within the KCC has facilitated numerous collaborative studies and publications that have contributed to im portant advances in cancer research. The KCC programs are supported by $78.3M in total sponsored funding. Funding comes from 73 NCI sponsored projects, including 2 inter-programmatic NCI program project grants, and totals $34.4M. The efforts of the Director and his recruits have resulted in increased philanthropic University and Hospital support. The importance of cancer research and care at Thomas Jefferson University is reflected in the Director's authority over clinical and research activities at the Institution, encompassing 144,208 sq. ft, and the construction of new facilities (232,114 sq. ft) including the new Breast Center, Oncology Center and research space. These new facilities will accommodate the basic, clinical and translational efforts of the KCC investigators. These new KCC facilities will enhance even further the translational cancer research effort of the Kimmel Cancer Center.