2013-2015 Bioenergetics Gordon Research Conference

2013-2015年生物能量学戈登研究会议

• 批准号: 8517951
• 负责人: Karlett J Parra
• 金额: $ 0.3万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-05-01 至 2014-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8517951
• 关键词: Academy; Address; Adoption; Affect; Aging; Anniversary; Area; Basic Science; Bioenergetics; Biological Aging; Biological Process; Biological Sciences; Biophysics; Cells; Chemistry; Communities; Complex; Defect; Development; Disease; Energy Metabolism; Fostering; Future; Goals; Health; Human; Human Pathology; Inborn Genetic Diseases; International; Knowledge; Lead; Malignant Neoplasms; Metabolic Diseases; Mitochondria; Molecular; Molecular Medicine; Nerve Degeneration; Oxidative Phosphorylation; Participant; Pathologic Processes; Physiological Processes; Postdoctoral Fellow; Process; Regulation; Request for Proposals; Research; Research Personnel; Role; Running; Scientist; Shapes; Site; Solutions; Structure; System; Techniques; Technology; Time; Training and Education; United States National Institutes of Health; Work; career; graduate student; human disease; insight; interest; meetings; multidisciplinary; next generation; novel; novel strategies; posters; programs; public health relevance; structural biology; symposium

DESCRIPTION (provided by applicant): This proposal requests partial support for the Bioenergetics Gordon Research Conference (GRC) (2 conferences) to be held at Proctor Academy, June 23 - June 28, 2013, and in the summer of 2015 at yet to be determined site. Bioenergetics is a fundamental cellular mechanism affecting aging and a wide spectrum of major human disease, including cancer, neurodegeneration, and metabolic disorders. Celebrating its 50th anniversary in 2013, the Bioenergetics GRCs have witnessed, shaped and fostered a remarkable scientific development both in terms of understanding its basic mechanisms and its impact on an ever increasing scope of human disease. The broad and long term goal of this GRC is to promote an integrated approach for the expanding role of molecular and cellular bioenergetics in physiological and pathological processes that underlie human aging and diseases. The Bioenergetics GRC offers a venue to communicate progress toward an understanding of mitochondrial energy transduction and the consequences of defects in oxidative phosphorylation. The specific aims of these meetings will be to convene about 32 speakers and discussion leaders that represent critical areas of bioenergetics research with a total of over 130 participants for two (2013, 2015) five day conferences. The program in 2013 will feature eight sessions that broadly address current issues in bioenergetic systems in health and disease, including adaptation, structures, functions, mechanisms, supramolecular organizations, and emerging techniques. In addition, poster presenter short talks and discussion session will permit all participants to contribute to these topics. In 2015, a similar program will cover fundamental structural and mechanistic aspects of bioenergetic systems and place continued and increased emphasis on its role in aging, neurodegeneration, metabolic disease, and cancer. The significance of this application is that the Bioenergetics GRC is the premier international scientific meeting covering nearly all aspects in the continuously expanding field of bioenergetics. These conferences direct and propel a broad community of bioenergetics scholars by gathering premier senior and the most promising junior international scientists who represent the future leader in this field. They provide opportunities for graduate students and post-docs to present their work in poster format and exchange ideas with leaders in the field thus, nurturing the next generation of bioenergetics research leaders. The health relatedness of this application is that bioenergetics is a fundamental biological process that impacts nearly all facets of human health. Altered energy metabolism is causative for a significant number of inherited disorders and is involved in biological aging, neurodegeneration, cancer, metabolic diseases, etc.

描述（由申请人提供）：本提案要求对将于2013年6月23日至28日在普罗克特学院举行的生物能量学戈登研究会议（GRC）（2次会议）提供部分支持，并于2015年夏季在待定地点举行。生物能量学是影响衰老和广泛的主要人类疾病的基本细胞机制，包括癌症，神经变性和代谢紊乱。在2013年庆祝其成立50周年之际，生物能量学GRCs见证了，塑造和促进了一个显着的科学发展，无论是在理解其基本机制及其对人类疾病范围不断扩大的影响方面。该GRC的广泛和长期目标是促进分子和细胞生物能量学在人类衰老和疾病的生理和病理过程中发挥更大作用的综合方法。生物能量学GRC提供了一个场所，以交流对线粒体能量转导的理解和氧化磷酸化缺陷的后果的进展。这些会议的具体目标将是召集约32位代表生物能量学研究关键领域的演讲者和讨论领导人，共有130多名与会者参加两次（2013年，2015年）为期五天的会议。该计划将在2013年举行八次会议，广泛讨论健康和疾病中生物能量系统的当前问题，包括适应，结构，功能，机制，超分子组织和新兴技术。此外，海报展示者的简短演讲和讨论会将允许所有参与者对这些主题做出贡献。2015年，一个类似的计划将 涵盖生物能量系统的基本结构和机械方面，并继续强调其在衰老，神经变性，代谢疾病和癌症中的作用。这一申请的意义在于，生物能量学GRC是首屈一指的国际科学会议，涵盖了不断扩大的生物能量学领域的几乎所有方面。 生物能量学这些会议通过聚集代表该领域未来领导者的高级和最有前途的初级国际科学家来指导和推动生物能量学学者的广泛社区。他们为研究生和博士后提供机会，以海报形式展示他们的工作，并与该领域的领导者交流思想，从而培养下一代生物能量学研究领导者。这种应用的健康相关性是生物能量学是一种基本的生物过程，几乎影响人类健康的所有方面。改变的能量代谢是大量遗传性疾病的原因，并且涉及生物老化、神经变性、癌症、代谢疾病等。