2013-2015 Bioenergetics Gordon Research Conference

2013-2015年生物能量学戈登研究会议

• 批准号: 8517951
• 负责人: Karlett J Parra
• 金额: $ 0.3万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-05-01 至 2014-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8517951
• 关键词: Academy; Address; Adoption; Affect; Aging; Anniversary; Area; Basic Science; Bioenergetics; Biological Aging; Biological Process; Biological Sciences; Biophysics; Cells; Chemistry; Communities; Complex; Defect; Development; Disease; Energy Metabolism; Fostering; Future; Goals; Health; Human; Human Pathology; Inborn Genetic Diseases; International; Knowledge; Lead; Malignant Neoplasms; Metabolic Diseases; Mitochondria; Molecular; Molecular Medicine; Nerve Degeneration; Oxidative Phosphorylation; Participant; Pathologic Processes; Physiological Processes; Postdoctoral Fellow; Process; Regulation; Request for Proposals; Research; Research Personnel; Role; Running; Scientist; Shapes; Site; Solutions; Structure; System; Techniques; Technology; Time; Training and Education; United States National Institutes of Health; Work; career; graduate student; human disease; insight; interest; meetings; multidisciplinary; next generation; novel; novel strategies; posters; programs; public health relevance; structural biology; symposium

DESCRIPTION (provided by applicant): This proposal requests partial support for the Bioenergetics Gordon Research Conference (GRC) (2 conferences) to be held at Proctor Academy, June 23 - June 28, 2013, and in the summer of 2015 at yet to be determined site. Bioenergetics is a fundamental cellular mechanism affecting aging and a wide spectrum of major human disease, including cancer, neurodegeneration, and metabolic disorders. Celebrating its 50th anniversary in 2013, the Bioenergetics GRCs have witnessed, shaped and fostered a remarkable scientific development both in terms of understanding its basic mechanisms and its impact on an ever increasing scope of human disease. The broad and long term goal of this GRC is to promote an integrated approach for the expanding role of molecular and cellular bioenergetics in physiological and pathological processes that underlie human aging and diseases. The Bioenergetics GRC offers a venue to communicate progress toward an understanding of mitochondrial energy transduction and the consequences of defects in oxidative phosphorylation. The specific aims of these meetings will be to convene about 32 speakers and discussion leaders that represent critical areas of bioenergetics research with a total of over 130 participants for two (2013, 2015) five day conferences. The program in 2013 will feature eight sessions that broadly address current issues in bioenergetic systems in health and disease, including adaptation, structures, functions, mechanisms, supramolecular organizations, and emerging techniques. In addition, poster presenter short talks and discussion session will permit all participants to contribute to these topics. In 2015, a similar program will cover fundamental structural and mechanistic aspects of bioenergetic systems and place continued and increased emphasis on its role in aging, neurodegeneration, metabolic disease, and cancer. The significance of this application is that the Bioenergetics GRC is the premier international scientific meeting covering nearly all aspects in the continuously expanding field of bioenergetics. These conferences direct and propel a broad community of bioenergetics scholars by gathering premier senior and the most promising junior international scientists who represent the future leader in this field. They provide opportunities for graduate students and post-docs to present their work in poster format and exchange ideas with leaders in the field thus, nurturing the next generation of bioenergetics research leaders. The health relatedness of this application is that bioenergetics is a fundamental biological process that impacts nearly all facets of human health. Altered energy metabolism is causative for a significant number of inherited disorders and is involved in biological aging, neurodegeneration, cancer, metabolic diseases, etc.

描述（由申请人提供）：该提案要求对生物能量戈登研究会议（GRC）（2个会议）的部分支持，将于2013年6月23日至6月28日在Proctor Academy举行，并在2015年夏季尚未确定地点。生物能力是一种基本的细胞机制，影响衰老和广泛的主要人类疾病，包括癌症，神经变性和代谢性疾病。在2013年庆祝其成立50周年，生物能力GRC在了解其基本机制及其对不断增长的人类疾病范围的影响方面见证，塑造和促进了非凡的科学发展。该GRC的广泛而长期的目标是促进一种综合方法，以扩大分子和细胞生物能学在人类衰老和疾病基础的生理和病理过程中的扩大作用。生物能力GRC提供了一个场所，可以传达对线粒体能量转导和氧化磷酸化缺陷的后果的进展。这些会议的具体目的是召集大约32名演讲者和讨论领导者，代表生物能力研究的关键领域，共有130多名参与者（2013年，2015年）为期5天。该计划将在2013年举办八个会议，这些会议详细介绍了健康和疾病中生物能体系中的当前问题，包括适应，结构，功能，机制，超分子组织和新兴技术。此外，海报主持人的简短会谈和讨论会议将使所有参与者都能为这些主题做出贡献。在2015年，类似的计划将 涵盖生物能系统的基本结构和机械方面，并继续进行地位，并越来越重视其在衰老，神经变性，代谢疾病和癌症中的作用。该应用的意义在于，生物能量GRC是国际首屈一指的大会，涵盖了几乎不断扩大领域的所有方面 生物能学。这些会议通过聚集了代表该领域的未来领导者的最有前途的初级科学家，指导并推动广泛的生物能学者学者社区。他们为研究生和博士后提供了机会，以海报格式介绍他们的作品，并与该领域的领导者交流想法，从而培养下一代的生物能力研究领导者。该应用的健康相关性是，生物能学是一个基本的生物学过程，几乎影响了人类健康的所有方面。能量代谢改变是大量遗传性疾病的原因，并且参与了生物衰老，神经退行性，癌症，代谢疾病等。