The Global Partnership for AIDS Behavioral Research: South Africa and U.S.

描述(由申请人提供)：在南非，艾滋病毒继续未经控制，农村地区妇女的感染率在过去10年中翻了一番。南非在生物医学创新方面拥有丰富的科学专长，但如果要缩小公平差距，最近确定的生物医学干预措施的成功实施和推广将需要提高艾滋病毒行为方面的专门知识，特别是在高度边缘化的人群中。全球艾滋病行为研究伙伴关系(GPABR)是一个旨在：1)建设StellenBosch大学及其在南非的合作伙伴的科学能力，使其成为具有行为艾滋病毒专业知识的关键研究中心；2)确定和实施关于艾滋病毒联合预防、移动和快速诊断技术的使用以及适应循证干预(EBI)的行为研究议程；以及3)将教师、学生、顾问和基础设施工作人员联系起来。在正在进行的科学合作的基础上，GPABR将是来自StellenBosch大学、加州大学洛杉矶分校(UCLA)和埃默里大学的跨学科研究人员之间的合作。GPABR的基础设施核心和研究项目开发核心将动员科学家、倡导者、社区和卫生系统提供者和消费者转化StellenBosch大学社会科学中的艾滋病毒研究专业知识。我们将把研究重点放在东开普省一个高度农村的地点，以及开普敦郊区的地点。基础设施核心将：制定艾滋病毒行为研究议程；支持IRB的提交、出版物和赠款；促进多样化的跨学科研究团队。研究项目开发核心将：进行年度试点赠款竞争，并进行同行审查程序。我们预计GPABR的影响将体现在研究人员和研究产品的数量和质量、美国与南非的合作以及学员和教职员工对指导质量的评级上。总体而言，GPABR的目标是建立HLV行为科学家、科学和网络，以减少南非的艾滋病毒感染，并与全球合作伙伴分享专业知识。

DESCRIPTION (provided by applicant): HIV continues unchecked in South Africa, with rates of infection among women in rural areas doubling in the last 10 years. South Africa has significant scientific expertise in biomedical innovations, yet the successful implementation and scale up of recently-identified biomedical interventions will require enhanced HIV behavioral expertise, particularly among highly marginalized populations, if the equity gap is to be reduced. The Global Partnership for AIDS Behavioral Research (GPABR) is an organizational structure aiming: 1) to build the scientific capacity of Stellenbosch University and its partners in South Africa to be a key research center with behavioral HIV expertise; 2) to identify and implement a behavioral research agenda regarding HIV combination prevention, the use of mobile and rapid diagnostic technologies, and adapting evidence- based interventions (EBI); and 3) to network faculty, students, consultants, and infrastructure staff. Building on ongoing scientific collaborations, GPABR will be a collaboration among interdisciplinary researchers from Stellenbosch University, the University of California, Los Angeles (UCLA), and Emory University. An Infrastructure Core and a Research Project Development Core of the GPABR will mobilize scientists, advocates, community and health system providers and consumers to transform HIV research expertise in the social sciences at Stellenbosch University. We will focus our research in a highly rural site in the Eastern Cape, as well as peri-urban Cape Town sites. The Infrastructure Core will: set an HIV behavioral research agenda; support IRB submissions, publications, and grants; promote diverse interdisciplinary research teams. The Research Project Development Core will: conduct an annual competition for pilot grants and conduct a peer review process. We anticipate the impact of the GPABR will be demonstrated in the number and quality of researchers and research products, U.S.-South Africa collaborations; and ratings of trainees and faculty on the quality of mentoring. Overall, GPABR aims to build HlV behavioral scientists, science, and networks to reduce HIV in South Africa and to share expertise with partners globally.