Minority Populations Resource Core

描述（由申请人提供）：为响应RFA-AA-12-010，本U24申请建议在布朗大学酒精研究中心（ARCH; P01AA019072, Monti， PI）内建立性少数群体资源核心（“SMP核心”）。布朗大学ARCH的中心主题是：(i)通过基础科学、干预科学和转化科学，开展酒精与艾滋病毒相互作用的最先进、综合和多学科研究；（ii）作为地方、区域和国家的酒精性艾滋病毒研究和传播资源。SMP核心的首要目标是通过在美国性少数群体中进行理论驱动的分析和支持艾滋病毒风险和酒精以及其他健康挑战共同发生的调查，扩展和加强布朗大学ARCH。SMP核心将特别强调分析和调查男男性行为者的种族/族裔亚群体和其他性少数群体在艾滋病毒风险和酒精方面的健康差异，重点关注非裔美国人和西班牙裔男男性行为者之间的差异。这将通过三个具体目标来实现：(i)对现有大型调查数据集进行汇编和基于理论的二次分析，这些数据集包括艾滋病毒、酒精以及男男性行为者和其他性少数群体中共同出现的挑战的措施；（二）综合和严格评价与这些人群中艾滋病毒、酒精和共存挑战有关的预防和干预科学研究状况；㈢与布朗大学、其他附属机构的科学家和社区团体开展合作，传播研究成果，并将成果转化为解决男男性行为者和其他性少数群体中艾滋病毒和酒精问题的新举措。这些活动将促进美国国立卫生研究院艾滋病研究办公室、NIAAA、国家艾滋病政策办公室和医学研究所的目标，加强对受艾滋病毒、酒精和相关健康挑战影响最严重的人群的研究和干预。

DESCRIPTION (provided by applicant): In response to RFA-AA-12-010, this U24 application proposes to form a Sexual Minority Populations Resource Core ("SMP Core") within the Brown University Alcohol Research Center on HIV (ARCH; P01AA019072, Monti, PI). The central themes of the Brown University ARCH are (i) to conduct state-of-the art, integrative, and multidisciplinary research on alcohol-HIV interactions through basic, intervention, and translational science; (ii) to serve as a local, regional, and national resource for alcohol-HIV research and dissemination. The overarching objective of the SMP Core is to extend and enhance the Brown University ARCH by conducting theory-driven analyses and supporting investigations on the co-occurrence of HIV risk and alcohol, and other health challenges, among sexual minority populations in the United States. The SMP Core will place special emphasis on analysis and investigations of health disparities in HIV risk and alcohol among racial/ethnic subgroups of MSM and other sexual minority populations, with a focus on disparities among African American and Hispanic MSM. This will be achieved through three specific aims: (i) compiling and performing theory-based secondary analysis of existing large survey datasets that include measures of HIV, alcohol, and co-occurring challenges in MSM and other sexual minority populations; (ii) synthesizing and critically appraising the state of prevention and intervention science research related to HIV, alcohol, and co-occurring challenges in these populations; (iii) developing collaborations with scientists at Brown University, other affiliated institutions, and with community groups in order to disseminate research and translate findings into new initiatives addressing HIV and alcohol in MSM and other sexually minority populations. These activities will advance the goals of the NIH Office of AIDS Research, NIAAA, as well as the Office of National AIDS Policy and the Institute of Medicine toward strengthening research and intervention in the populations most severely affected by HIV, alcohol, and related health challenges.