Minority Populations Resource Core

描述(由申请人提供)：为响应RFA-AA-12-010，本U24申请建议在布朗大学艾滋病毒酒精研究中心(ARCH；P01AA019072，蒙蒂，PI)内形成一个性少数群体资源核心(SMP核心)。布朗大学ARCH的中心主题是(I)通过基础科学、干预学和转化科学对酒精与艾滋病毒的相互作用进行最先进的、综合的和多学科的研究；(Ii)作为酒精与艾滋病毒研究和传播的地方、地区和国家资源。SMP核心的总体目标是通过对美国性少数群体中艾滋病毒风险和酒精以及其他健康挑战的共同出现进行理论驱动的分析和支持调查，来扩展和加强布朗大学的ARCH。SMP核心将特别重视分析和调查MSM种族/民族亚群和其他性少数群体在艾滋病毒风险和酒精方面的健康差异，重点是非裔美国人和西班牙裔MSM之间的差异。这将通过三个具体目标来实现：(I)对现有的大型调查数据集进行基于理论的二级分析，其中包括对MSM和其他性少数群体中艾滋病毒、酒精和共生挑战的测量；(Ii)综合和批判性地评估与这些人群中艾滋病毒、酒精和共生挑战有关的预防和干预科学研究的状况；(Iii)与布朗大学、其他附属机构和社区团体发展合作，以便传播研究成果，并将研究结果转化为解决MSM和其他性少数群体中艾滋病毒和酒精问题的新举措。这些活动将推进NIH艾滋病研究办公室、国家艾滋病政策办公室和医学研究所的目标，以加强对受艾滋病毒、酒精和相关健康挑战影响最严重的人群的研究和干预。

DESCRIPTION (provided by applicant): In response to RFA-AA-12-010, this U24 application proposes to form a Sexual Minority Populations Resource Core ("SMP Core") within the Brown University Alcohol Research Center on HIV (ARCH; P01AA019072, Monti, PI). The central themes of the Brown University ARCH are (i) to conduct state-of-the art, integrative, and multidisciplinary research on alcohol-HIV interactions through basic, intervention, and translational science; (ii) to serve as a local, regional, and national resource for alcohol-HIV research and dissemination. The overarching objective of the SMP Core is to extend and enhance the Brown University ARCH by conducting theory-driven analyses and supporting investigations on the co-occurrence of HIV risk and alcohol, and other health challenges, among sexual minority populations in the United States. The SMP Core will place special emphasis on analysis and investigations of health disparities in HIV risk and alcohol among racial/ethnic subgroups of MSM and other sexual minority populations, with a focus on disparities among African American and Hispanic MSM. This will be achieved through three specific aims: (i) compiling and performing theory-based secondary analysis of existing large survey datasets that include measures of HIV, alcohol, and co-occurring challenges in MSM and other sexual minority populations; (ii) synthesizing and critically appraising the state of prevention and intervention science research related to HIV, alcohol, and co-occurring challenges in these populations; (iii) developing collaborations with scientists at Brown University, other affiliated institutions, and with community groups in order to disseminate research and translate findings into new initiatives addressing HIV and alcohol in MSM and other sexually minority populations. These activities will advance the goals of the NIH Office of AIDS Research, NIAAA, as well as the Office of National AIDS Policy and the Institute of Medicine toward strengthening research and intervention in the populations most severely affected by HIV, alcohol, and related health challenges.