Training Program in Transplantation

移植培训计划

基本信息

  • 批准号:
    8500419
  • 负责人:
  • 金额:
    $ 9.44万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2004
  • 资助国家:
    美国
  • 起止时间:
    2004-04-01 至 2015-07-31
  • 项目状态:
    已结题

项目摘要

DESCRIPTION (provided by applicant): This is a resubmission of a competing renewal for a highly successful training program in transplantation immunology and stem cell biology. Over the past 11 years, a dynamic group of internationally recognized investigators in transplantation and stem cell biology were strategically recruited to the University of Louisville which is increasingly recognized for its comprehensive translational research in composite tissue allotransplantation, tolerance, and stem cell-mediated regenerative medicine. This training program directly addresses the mission of the NIH training grant program to help ensure that a diverse and highly trained workforce is available to assume leadership roles related to the nation's biomedical research agenda. All positions have been filled with outstanding applicants to date including six women (one minority), thereby addressing the major concern of all three reviewers. Applicants must have a Ph.D., D.V.M., or M.D. They are required to submit a CV, publication list, three letters of recommendation, and a statement of the specific research proposed. An Executive Training Committee comprised of the program Director and senior trainers selects the trainees. Trainees assemble a program and undertake basic research with one trainer and one or more co-mentors. Evaluation of the Training Program occurs on several levels, including manuscript and abstract submissions; oral presentations and participation at research seminar series; and completion and submission of an NRSA postdoctoral individual training grant or equivalent (AHA, JDRF, ASH, or other foundation or society fellowships) within the second year of training. The overall progress of this Training Program is assessed by an External Advisory Board through semiannual meetings and feedback. The External Advisory Board also assists in minority recruitment. The faculty in this training program has the expertise and breadth of background to successfully train fellows in well-equipped, centrally-located laboratories, it is our goal that our trainees will be qualified to assume leadership positions related to transplantation and stem cell biology in industry, academia, and biotechnology. Our established track record demonstrates that we are well on our way to achieving this goal.
描述(由申请人提供):这是一个非常成功的移植免疫学和干细胞生物学培训项目的重新申请。在过去的11年里,路易斯维尔大学战略性地招募了一批国际公认的移植和干细胞生物学研究人员,路易斯维尔大学在复合组织异体移植、耐受性和干细胞介导的再生医学方面的综合转化研究日益得到认可。该培训计划直接解决了NIH培训资助计划的任务,以帮助确保多样化和高度训练的劳动力可以承担与国家生物医学研究议程相关的领导角色。迄今为止,所有职位都有优秀的申请人填补,其中包括六名妇女(一个少数民族),从而解决了所有三名审查人员的主要关切。申请人必须具有博士学位,d.v.m.或M.D.。他们需要提交一份简历,出版清单,三封推荐信和一份具体研究计划的声明。由项目总监和高级培训师组成的执行培训委员会负责选拔学员。受训者与一名培训师和一名或多名共同导师组成一个项目并进行基础研究。培训计划的评估发生在几个层面,包括手稿和摘要提交;口头报告和参加研究系列讨论会;并在培训的第二年完成并提交NRSA博士后个人培训资助或同等资助(AHA, JDRF, ASH或其他基金会或社会奖学金)。该培训计划的总体进展由外部咨询委员会通过半年度会议和反馈进行评估。外部咨询委员会也协助少数民族的征聘工作。该培训项目的教师具有专业知识和广泛的背景,可以在设备齐全的中心实验室成功培训研究员,我们的目标是我们的学员将有资格在工业,学术界和生物技术领域担任与移植和干细胞生物学相关的领导职位。我们已有的记录表明,我们正在朝着实现这一目标的方向前进。

项目成果

期刊论文数量(3)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Immunomodulation with SA-FasL protein as an effective means of preventing islet allograft rejection in chemically diabetic NOD mice.
  • DOI:
    10.1016/j.transproceed.2013.01.041
  • 发表时间:
    2013-06
  • 期刊:
  • 影响因子:
    0.9
  • 作者:
    Yolcu, E. S.;Zhao, H.;Shirwan, H.
  • 通讯作者:
    Shirwan, H.
Evidence that FoxP3+ regulatory T cells may play a role in promoting long-term acceptance of composite tissue allotransplants.
  • DOI:
    10.1097/tp.0b013e31820fafb4
  • 发表时间:
    2011-04-27
  • 期刊:
  • 影响因子:
    6.2
  • 作者:
    Bozulic LD;Wen Y;Xu H;Ildstad ST
  • 通讯作者:
    Ildstad ST
Posttransplantation systemic immunomodulation with SA-FasL-engineered donor splenocytes has robust efficacy in preventing cardiac allograft rejection in mice.
使用 SA-FasL 改造的供体脾细胞进行移植后全身免疫调节在预防小鼠心脏同种异体移植排斥方面具有强大的功效。
  • DOI:
    10.1016/j.transproceed.2013.01.049
  • 发表时间:
    2013
  • 期刊:
  • 影响因子:
    0.9
  • 作者:
    Zhao,H;Woodward,KB;Shirwan,H;Grimany-Nuno,O;Yolcu,ES
  • 通讯作者:
    Yolcu,ES
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SUZANNE T ILDSTAD其他文献

SUZANNE T ILDSTAD的其他文献

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{{ truncateString('SUZANNE T ILDSTAD', 18)}}的其他基金

Delayed Tolerance Induction in Living Related Donor Renal Transplant Recipients
与生活相关的供体肾移植受者的延迟耐受诱导
  • 批准号:
    8252790
  • 财政年份:
    2012
  • 资助金额:
    $ 9.44万
  • 项目类别:
Tolerance Induction to Islet Transplants
胰岛移植耐受诱导
  • 批准号:
    8003242
  • 财政年份:
    2010
  • 资助金额:
    $ 9.44万
  • 项目类别:
Tolerance Induction to Islet Transplants
胰岛移植耐受诱导
  • 批准号:
    7488881
  • 财政年份:
    2005
  • 资助金额:
    $ 9.44万
  • 项目类别:
Induction of Donor Tolerance in Renal Transplants
肾移植中诱导供体耐受
  • 批准号:
    8058450
  • 财政年份:
    2005
  • 资助金额:
    $ 9.44万
  • 项目类别:
AMD-FCRx to Restore Damaged Pigment Epithelium
AMD-FCRx 可恢复受损的色素上皮
  • 批准号:
    6991727
  • 财政年份:
    2005
  • 资助金额:
    $ 9.44万
  • 项目类别:
Tolerance Induction to Islet Transplants
胰岛移植耐受诱导
  • 批准号:
    6970186
  • 财政年份:
    2005
  • 资助金额:
    $ 9.44万
  • 项目类别:
Tolerance Induction to Islet Transplants
胰岛移植耐受诱导
  • 批准号:
    7279886
  • 财政年份:
    2005
  • 资助金额:
    $ 9.44万
  • 项目类别:
Tolerance Induction to Islet Transplants
胰岛移植耐受诱导
  • 批准号:
    7674545
  • 财政年份:
    2005
  • 资助金额:
    $ 9.44万
  • 项目类别:
Induction of Donor Tolerance in Renal Transplants
肾移植中诱导供体耐受
  • 批准号:
    8333414
  • 财政年份:
    2005
  • 资助金额:
    $ 9.44万
  • 项目类别:
Tolerance Induction to Islet Transplants
胰岛移植耐受诱导
  • 批准号:
    7113228
  • 财政年份:
    2005
  • 资助金额:
    $ 9.44万
  • 项目类别:

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PFI (MCA):利用口腔微生物移植改进牙科技术
  • 批准号:
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  • 批准号:
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Regeneration of Retina with Physiological Functions by Hybrid Culture and Evaluation of Drugs / Production of Novel iPS Cells for Transplantation.
通过混合培养和药物评估/生产用于移植的新型 iPS 细胞来再生具有生理功能的视网膜。
  • 批准号:
    23K09017
  • 财政年份:
    2023
  • 资助金额:
    $ 9.44万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
The Phenomenon of Stem Cell Aging according to Methylation Estimates of Age After Hematopoietic Stem Cell Transplantation
根据造血干细胞移植后甲基化年龄估算干细胞衰老现象
  • 批准号:
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  • 财政年份:
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Basic research on Muse cell transplantation for Duchenne muscular dystrophy
Muse细胞移植治疗杜氏肌营养不良症的基础研究
  • 批准号:
    23K05627
  • 财政年份:
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Tailoring an Optimal Immune System for Each Patient: A Café Scientifique series hosted by the Canadian Donation and Transplantation Research Program.
为每位患者量身定制最佳免疫系统:由加拿大捐赠和移植研究计划主办的 Café Scientifique 系列。
  • 批准号:
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