In Vitro Testing Resources for AIDS Therapeutics Dev: Specialized Assays

艾滋病治疗开发的体外测试资源：专门化验

• 批准号: 8730037
• 负责人: MARINTHA HEIL
• 金额: $ 317.49万
• 依托单位: SOUTHERN RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-09-24 至 2014-09-23
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8730037
• 关键词: Acquired Immunodeficiency Syndrome; Biochemical; Biological Assay; Cells; Development; Drug toxicity; HIV; In Vitro; Local Microbicides; Resources; Therapeutic; Tissues; base; drug testing; in vitro testing; microbicide

To perform in vitro specialized testing of drug substances submitted to DAIDS for development as potential anti-HIV topical microbicides and anti-HIV therapeutics. Develop and conduct biochemical, cell-based, and tissue-based assays to evaluate both the efficacy and toxicity of the drug substances against HIV as theraputics or microbicides.

对提交给 DAIDS 开发的潜在抗 HIV 局部杀菌剂和抗 HIV 疗法的药物进行体外专门测试。 开发并进行基于细胞和组织的生化检测，以评估药物作为治疗剂或杀菌剂对抗 HIV 的功效和毒性。