In Vitro Testing Resources for AIDS Therapeutics Dev: Specialized Assays

艾滋病治疗开发的体外测试资源：专门化验

• 批准号: 8550707
• 负责人: MARINTHA HEIL
• 金额: $ 317.97万
• 依托单位: SOUTHERN RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-09-24 至 2013-09-23
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8550707
• 关键词: Acquired Immunodeficiency Syndrome; Biochemical; Biological Assay; Cells; Development; Drug toxicity; HIV; In Vitro; Local Microbicides; Resources; Therapeutic; Tissues; base; drug testing; in vitro testing; microbicide

To perform in vitro specialized testing of drug substances submitted to DAIDS for development as potential anti-HIV topical microbicides and anti-HIV therapeutics. Develop and conduct biochemical, cell-based, and tissue-based assays to evaluate both the efficacy and toxicity of the drug substances against HIV as theraputics or microbicides.

对提交给DAIDS用于开发潜在抗HIV局部杀微生物剂和抗HIV治疗剂的原料药进行体外专门检测。 开发并进行生物化学、细胞和组织分析，以评价原料药作为治疗剂或杀微生物剂抗HIV的有效性和毒性。