Preventing tobacco use among adolescents in Uruguay: Project Activate

描述（由申请人提供）：本提案是根据福格蒂国际烟草与健康研究和能力建设项目第三轮RFA-TW-11-003提交的。本项目的研究目标是设计、提供和评估一种文化上适宜的、协调的多成分干预措施，以预防和减少乌拉圭蒙得维的亚青少年的烟草使用。这次干预被称为“行动起来！”将以已知的以证据为基础的干预战略为基础，这些战略可在高收入（如美国）和低收入（如印度）国家预防和减少年轻人的烟草使用，并“转化”用于这个中等收入国家。鉴于新的研究表明，促进身体活动实际上可以预防烟草使用，将采用额外的干预策略来鼓励和支持身体活动。鉴于乌拉圭目前存在的全面监管环境以及我们对现有证据基础和其中的基本要素的使用，我们预计对烟草使用产生短期和长期影响，并将对此进行测试。干预措施的有效性将在一项分组随机对照试验中进行评估，该试验将在乌拉圭蒙得维的亚对3200名青年进行为期3年的跟踪研究。能力建设将是我们研究计划的一个重要组成部分。能力建设战略将为非洲的公共卫生专业人员提供多种培训机会

DESCRIPTION (provided by applicant): This proposal is being submitted in response to RFA-TW-11-003, the third round of Fogarty's International Tobacco and Health Research and Capacity Building Program. The research goal of this project is to design, deliver, and evaluate a culturally-appropriate, coordinated, multiple component intervention to prevent and reduce tobacco use among adolescents in Montevideo, Uruguay. The intervention, called ¿Act¿vate!, will be grounded in evidence-based intervention strategies known to prevent and reduce tobacco use among young people in high-income (e.g., United States) and low-income (e.g., India) nations, "translated" for use in this middle-income country. Additional intervention strategies wil be employed to encourage and support physical activity, given new studies that suggest that promoting physical activity could actually prevent tobacco use. Given the comprehensive regulatory environment that currently exists in Uruguay and our use of the existing evidence-base and essential elements therein, we anticipate short- and long-term effects on tobacco use and will test for that. The efficacy of the intervention will be evaluated in a group-randomized, controlled trial that will follow a cohort of 3,200 youth in Montevideo, Uruguay over 3 years. Capacity building will be an integrated and significant part of our research program. Capacity building strategies will provide multiple training opportunities for public health professionals in Uruguay and the United States to suitably apply and enhance their skills specific to designing, implementing, and monitoring behavioral interventions for Latin American youth and conducting and evaluating large-scale research studies with adolescents. Capacity building activities will also engage and activate young people, their parents, and other community members to take action to prevent the onset and progression of tobacco use among adolescents in Uruguay. The US-based team is with the School of Public Health, University of Texas. They are well-positioned to lead this study, having been successful recipients of Fogarty funding in the previous two rounds of this mechanism. The Uruguay-based team is with CIET, the Tobacco Epidemic Research Center in Uruguay. CIET is at the forefront of tobacco control research, practice, and advocacy in Uruguay (and across the region of Latin America), well-known for their work with civil society and government officials, both locally and internationally. PUBLIC HEALTH RELEVANCE: This proposal is a collaborative endeavor between scientists in the United States and Uruguay. The research project focuses on designing, delivering, and evaluating a culturally-appropriate, multiple component intervention to prevent and reduce tobacco use among youth in Uruguay. This intervention, called ¿Act¿vate!, is grounded in evidence-based intervention strategies that will be "translated" for use in Uruguay and tested in a group-randomized trial of 3,200 youth (12- 14 years old). Capacity building strategies will support the development of health professionals in Uruguay and the United States, as well as youth, parents, and community members affiliated with ¿Act¿vate!,