Individualizing cytomegalovirus preventative strategies following solid organ transplantation: a precision medicine approach

实体器官移植后个体化巨细胞病毒预防策略：精准医学方法

• 批准号: nhmrc : GNT1150351
• 负责人: Dr Bradley Gardiner
• 金额: $ 12.64万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Postgraduate Scholarships
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/individualizing-cytomegalovirus-preventative-medicine-approach/1348924
• 关键词: Individualizing; cytomegalovirus; preventative; strategies; following

Cytomegalovirus (CMV) infection is a significant contributor to poor outcomes following solid organ transplantation. Current preventative strategies are somewhat effective but treat groups of patients similarly rather than targeting the individual, so many patients are treated unnecessarily & breakthrough disease still occurs. We propose a program of research directed towards individualizing CMV prevention strategies in solid organ transplant recipients, incorporating new diagnostic tests.

巨细胞病毒（CMV）感染是实体器官移植后不良结局的重要因素。目前的预防策略在一定程度上是有效的，但对患者群体进行类似的治疗，而不是针对个人，因此许多患者接受了不必要的治疗，突破性疾病仍然发生。我们提出了一项针对实体器官移植受者个体化CMV预防策略的研究计划，并结合新的诊断测试。