Body Image and Self-care in HIV-infected MSM

HIV 感染 MSM 的身体形象和自我护理

• 批准号: 8497752
• 负责人: Aaron J Blashill
• 金额: $ 17.06万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-07-01 至 2017-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8497752
• 关键词: AIDS prevention; AIDS/HIV problem; Acute; Address; Adherence; Affect; Alcohol or Other Drugs use; Anus; Appearance; Area; Attention; Award; Behavior; Behavior Therapy; Behavioral; Body Image; Caring; Chemoprophylaxis; Child Sexual Abuse; Cities; Clinical Trials; Control Groups; Data; Development Plans; Face; General Hospitals; Goals; Grant; HIV; HIV risk; Health; Health behavior; Highly Active Antiretroviral Therapy; Individual; Intervention; Interview; Life; Link; Massachusetts; Mental Depression; Mental Health; Mental disorders; Mentors; Mentorship; Meta-Analysis; Mid-Career Clinical Scientist Award (K24); Modeling; Outcome; Participant; Peer Review; Population; Positioning Attribute; Postdoctoral Fellow; Preventive Intervention; Process; Prophylactic treatment; Public Health; Publications; Quality of life; Randomized; Randomized Controlled Trials; Research; Research Personnel; Research Project Grants; Risk; Risk Behaviors; Risk Reduction; Role; Secondary Prevention; Self Care; Sexual Transmission; Substance abuse problem; Testing; Training; Treatment Efficacy; Virus; active control; antiretroviral therapy; arm; behavior change; body dissatisfaction; career; career development; condoms; design; efficacy testing; experience; high risk; improved; medical schools; medication compliance; men who have sex with men; novel; primary outcome; prospective; psychosocial; research and development; secondary outcome; sex risk; skills; therapy development; transmission process; treatment as usual; trial comparing; uptake

DESCRIPTION (provided by applicant): This is an amended, previously well-received, K23 proposal addressing health risk behaviors in men who have sex with men (MSM) within the context of syndemics (co-occurring psychosocial problems), and a particular focus on body image disturbance and depression. MSM constitute, by far, the largest number (H60%) of individuals with HIV in the U.S. Modest effects of behavioral interventions for MSM may be because they generally do not address the unique and varied psychosocial context for this population. Study after study concludes that co-occurring syndemics contribute to poor self-care behaviors including, sexual risk and HAART non-adherence, and may interfere with uptake of interventions for MSM1-7. One example of an understudied psychosocial problem among HIV-infected MSM is dissatisfaction with one's appearance. It is estimated that 31% of HIV-infected MSM have elevated body dissatisfaction8, which is syndemic to depression, sexual transmission risk, and HAART non-adherence. CANDIDATE: I am a postdoctoral fellow at Massachusetts General Hospital/Harvard Medical School with 15 peer-reviewed publications (12 first-authored) on psychosocial problems such as body dissatisfaction and depression among MSM, HAART adherence, and HIV sexual transmission risk behaviors. The present proposal will allow me to acquire needed skills to achieve my goal of becoming an independent researcher studying co-occurring psychosocial and self-care problems among MSM living with and at risk for acquiring HIV. MENTORING: Dr. Steven Safren, the primary mentor, has expertise in addressing psychosocial problems in the context of interventions for self-care in HIV, including depression, HAART adherence, and HIV prevention. Drs. Kenneth Mayer and Sabine Wilhelm are secondary mentors and add considerable unique expertise to the mentoring team, with their respective research specializations in HIV prevention and body dissatisfaction interventions. RESEARCH: As an example of a way to integrate improving self-care behaviors while addressing an important psychosocial syndemic indicator, I will develop a novel intervention which addresses body dissatisfaction, syndemic to depression, secondary HIV prevention, and HAART adherence among HIV-infected MSM. With mentorship, this intervention will be developed through an initial iterative process, and then piloted in a randomized control trial. TRAINING: I will receive direct mentoring in addressing psychosocial problems in the context of self-care (HIV prevention and adherence), the iterative process of developing and testing interventions that focus on both psychosocial problems and self-care, as well as dissemination. This is directly tied to my primary mentor's K24 award (and his other grants), on which I can be part of, and observe the iterative intervention development related to syndemics. I will also receive training in advanced statistical analysis, take courses on clinical trials, longitudinal modeling, qualitative analysis, and missing data.

描述（由申请人提供）：这是一个经过修改的，以前已备受的K23提案，涉及与男性发生性关系的男性（MSM）的健康风险行为（共同发生的社会心理问题），并特别关注身体形象扰动和抑郁症。到目前为止，MSM构成了在美国对MSM行为干预措施中适度的艾滋病毒中最多的人（H60％），可能是因为它们通常无法解决该人群的独特和多样化的社会心理环境。一项研究的研究得出的结论是，同时发生的集团有助于自我保健行为不良，包括性风险和不遵守性，并且可能会干扰MSM1-7的干预措施。在感染HIV的MSM中，研究不足的社会心理问题的一个例子是对自己的外观不满意。据估计，感染HIV的MSM的31％的身体不满8，这是抑郁症，性传播风险和HAART不遵守的集团的升高。候选人：我是马萨诸塞州综合医院/哈佛医学院的博士后研究员，其中有15个经过同行评审的出版物（12个首次撰写），涉及社会心理问题，例如身体不满和MSM，HAART依从性和HIV HIV性传播风险行为。本提案将使我能够获得所需的技能，以实现我成为一名独立研究人员，研究在与获取HIV的MSM和有风险的MSM中共同出现的社会心理和自我保健问题。指导：主要导师史蒂文·萨夫伦（Steven Safren）博士在解决艾滋病毒自我护理的情况下，在包括抑郁症，哈特依从性和预防艾滋病毒的情况下解决社会心理问题的专业知识。博士。肯尼斯·梅耶（Kenneth Mayer）和萨宾·威廉（Sabine Wilhelm）是次要导师，并为指导团队增加了相当大的专业知识，并在各自的艾滋病毒预防和身体不满意干预方面进行了研究专业。研究：作为一种在解决重要的心理社会联合指标的同时整合改善自我保健行为的方法的例子，我将开发一种新颖的干预措施，以解决身体不满，对抑郁症，二次HIV预防和HAART的HAART遵守HIV感染的MSM。通过指导，将通过初始迭代过程制定这种干预措施，然后在随机对照试验中进行试验。培训：我将在自我保健（预防艾滋病毒和依从性）的背景下直接指导解决社会心理问题，这是开发和测试侧重于心理社会问题和自我保健的迭代过程，以及传播。这与我的主要导师K24奖（以及他的其他赠款）直接相关，我可以参与其中，并观察与Syndemics相关的迭代干预开发。我还将接受高级统计分析的培训，参加临床试验，纵向建模，定性分析和缺失数据的课程。