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Conte Center for Computational Systems Genomics of Neuropsychiatric Phenotypes

Conte Center for Computational Systems Genomics of Neuropsychiatric Phenotypes
孔特神经精神表型计算系统基因组学中心
批准号：
8337330
负责人：
ANDREY RZHETSKY
金额：
$207.83万
依托单位：
UNIVERSITY OF CHICAGO
依托单位国家：
美国
项目类别：
财政年份：
2011
资助国家：
美国
项目状态：
已结题
起止时间：
2011-09-22 至 2016-07-31
来源：
https://reporter.nih.gov/project-details/8337330
关键词：
Adverse effectsAdverse eventAffectAlgorithmsAnxietyBiologicalChromosome MappingClinicalCommunitiesComplementComplexComputing MethodologiesDataDatabasesDiagnostic testsDiseaseDrug usageElementsEnvironmental ExposureEnvironmental Risk FactorFailureGenesGeneticGenomicsGoalsHealthHumanLinkLiteratureMapsMental DepressionMental HealthMethodsMiningModelingMolecularMolecular ProbesNeurologicPathway interactionsPatternPharmaceutical PreparationsPharmacologyPhenotypePhysiciansPopulationProteinsPublishingResearchSchizophreniaScienceSymptomsSystemTestingTimeVariantanalytical tooldesigndisorder riskgene environment interactiongenetic associationmultiple drug useneuropsychiatrynovelpopulation basedresponsesuccesstext searching

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英文摘要
DESCRIPTION (provided by applicant): We aim to develop, test, and apply a drastically new computational methodology for the analysis of more than one complex phenotype at a time, with the goal of generating novel biological results. Specifically, we propose to design and validate a battery of novel analytical tools for the inference of causal relationships among human genomic variations, environmental factors, and more than one mental health phenotype, explicitly exploiting the genetic and environmental non-independence of complex (multigenic) disorders.
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2/2-Measuring translational dynamics and the proteome to identify potential brain biomarkers for psychiatric disease
  • 批准号：
    9313326
  • 项目类别：
  • 资助金额：
    $31.6万
  • 财政年份：
    2016
  • 负责人：
    ANDREY RZHETSKY
  • 依托单位：
    UNIVERSITY OF CHICAGO
2/2-Measuring translational dynamics and the proteome to identify potential brain biomarkers for psychiatric disease
  • 批准号：
    9173991
  • 项目类别：
  • 资助金额：
    $31.6万
  • 财政年份：
    2016
  • 负责人：
    ANDREY RZHETSKY
  • 依托单位：
    UNIVERSITY OF CHICAGO
Conte Center for Computational Systems Genomics of Neuropsychiatric Phenotypes
  • 批准号：
    8531353
  • 项目类别：
  • 资助金额：
    $197.01万
  • 财政年份：
    2011
  • 负责人：
    ANDREY RZHETSKY
  • 依托单位：
    UNIVERSITY OF CHICAGO
Administration, education and outreach
  • 批准号：
    8935635
  • 项目类别：
  • 资助金额：
    $10.0万
  • 财政年份：
    2011
  • 负责人：
    ANDREY RZHETSKY
  • 依托单位：
    UNIVERSITY OF CHICAGO
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