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中文摘要
翻译
总结 我们的总体项目目标是系统地连接c/s-调控元件IRI前mRNA的RNA结构特征,控制人类细胞中的替代前mRNA剪接。虽然前体mRNA结构在控制剪接事件中的作用已被研究用于单个基因,但对RNA结构与剪接控制的相互作用及其与遗传变异的关系的全面理解对于人类转录组尚不清楚。
英文摘要
Summary Our overall project goal is to systematically link c/s-regulatory elements iri pre-mRNAs to RNA structural features that control alternative pre-mRNA splicing in human cells. While the role of pre-mRNA structure in control of splicing events has been studied for individual genes, a comprehensive understanding of the interplay of RNA structure with splicing control¿and its relation to genetic variation¿is not known for the human transcriptome.
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Enabling High-Throughput Analysis and Single-Cell Imaging of Bacterial Signals
  • 批准号:
    10709561
  • 项目类别:
  • 资助金额:
    $35.57万
  • 财政年份:
    2017
  • 负责人:
    Ming Chen Hammond
  • 依托单位:
Enabling High-Throughput Analysis and Single-Cell Imaging of Bacterial Signals
  • 批准号:
    9368567
  • 项目类别:
  • 资助金额:
    $32.36万
  • 财政年份:
    2017
  • 负责人:
    Ming Chen Hammond
  • 依托单位:
Enabling High-Throughput Analysis and Single-Cell Imaging of Bacterial Signals
  • 批准号:
    10522177
  • 项目类别:
  • 资助金额:
    $35.48万
  • 财政年份:
    2017
  • 负责人:
    Ming Chen Hammond
  • 依托单位:
Enabling High-Throughput Analysis and Single-Cell Imaging of Bacterial Signals
  • 批准号:
    9744967
  • 项目类别:
  • 资助金额:
    $35.08万
  • 财政年份:
    2017
  • 负责人:
    Ming Chen Hammond
  • 依托单位:
海外基金