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中文摘要
翻译
摘要 我们的总体项目目标是系统地将c/S调节元件iri前-mRNAs与控制人类细胞中选择性前-mRNAs剪接的rna结构特征联系起来。虽然已经研究了前mRNA结构在单个基因剪接事件控制中的作用,但对于人类转录组来说,全面了解RNA结构与剪接控制的相互作用及其与遗传变异的关系尚不清楚。
英文摘要
Summary Our overall project goal is to systematically link c/s-regulatory elements iri pre-mRNAs to RNA structural features that control alternative pre-mRNA splicing in human cells. While the role of pre-mRNA structure in control of splicing events has been studied for individual genes, a comprehensive understanding of the interplay of RNA structure with splicing control¿and its relation to genetic variation¿is not known for the human transcriptome.
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Enabling High-Throughput Analysis and Single-Cell Imaging of Bacterial Signals
  • 批准号:
    10709561
  • 项目类别:
  • 资助金额:
    $35.57万
  • 财政年份:
    2017
  • 负责人:
    Ming Chen Hammond
  • 依托单位:
Enabling High-Throughput Analysis and Single-Cell Imaging of Bacterial Signals
  • 批准号:
    9368567
  • 项目类别:
  • 资助金额:
    $32.36万
  • 财政年份:
    2017
  • 负责人:
    Ming Chen Hammond
  • 依托单位:
Enabling High-Throughput Analysis and Single-Cell Imaging of Bacterial Signals
  • 批准号:
    10522177
  • 项目类别:
  • 资助金额:
    $35.48万
  • 财政年份:
    2017
  • 负责人:
    Ming Chen Hammond
  • 依托单位:
Enabling High-Throughput Analysis and Single-Cell Imaging of Bacterial Signals
  • 批准号:
    9744967
  • 项目类别:
  • 资助金额:
    $35.08万
  • 财政年份:
    2017
  • 负责人:
    Ming Chen Hammond
  • 依托单位:
海外基金