Clinical and Translational Science Award

这是阿尔伯特·爱因斯坦学院临床和传播学科学奖(CTSA)的申请书 医学与蒙特菲奥里医疗中心合作。爱因斯坦-蒙特菲奥里临床与移植研究所 国家研究(卢旺达问题国际法庭)是我们2007年创建的CTSA方案的大本营，作为正式研究 这两个研究所之间的伙伴关系。卢旺达问题国际法庭具有学术实体的地位，拥有承诺的空间。 和资源，以促进临床和跨领域研究(CTR)，并有权在 临床实习及其他培训和职业发展计划。卢旺达问题国际法庭已经改变了CTR 在我们的机构内，并为我们的城墙以外的重大变化做出了贡献。新的CTSA的目标是 1)提供综合资源和服务，以支持和加快规划、实施和 完成整个研究范围的CTR；2)提高CTR的质量、安全和效率 针对我们环境中的所有疾病和状况；3)开发新的创新，以促进临床和 翻译科学；4)促进强有力的翻译研究的培训和职业发展 劳动力。为了实现这些目标，我们提出了一种具有横切支持的积分五方法 T1-T4跨学科、可互操作的生物医学信息学、治疗学发展、儿童健康 研究，以及以患者和人群为中心的结果研究。我们还建议在研究的基础上 发展和扩展的核心服务包括：1)临床试验和监管支持办公室 (CTRSO)；2)临床信息服务核心(CISC)；3)生物统计学、流行病学和研究设计 (BERD)；4)生物标志物和分析研究核心(BARC)；5)生物信息库(BASER)； 6)社区参与咨询核心(CECC)；7)研究信息核心(RIC)；8)项目 加速资源(PAR)。我们的研究培训、教育和职业发展计划将 创造以学习者为中心的教育环境；专注于核心能力 由CTSA开发；提供选项菜单，为处于不同发展阶段的学习者提供服务 跨越临床和跨领域研究的范围；并实施新颖的指导方法。 相关性(请参阅说明)： 这项CTSA申请提出了一项研究所临床和跨性别科学奖(U54)计划， 符合促进跨国界科学的国家中心的使命，如RFA中所述- TR-12-006。

This is an applicafion for a Clinical and Translafional Science Award (CTSA) at the Albert Einstein College of Medicine partnered with Montefiore Medical Center. The Einstein-Montefiore Institute for Clinical and Trans- lational Research (ICTR) serves as the home of our CTSA program created in 2007 as the formal research partnership between the two institufions. The ICTR has status as an academic entity with committed space and resources, to advance clinical and translafional research (CTR), with authority to sponsor a PhD in clinical invesfigation and other training and career development programs. The ICTR has transformed CTR within our institufions, and contributed to significant changes beyond our walls. The goals for the new CTSA are; 1) To provide integrated resources and services to support and expedite planning, implementafion, and completion of CTR across the entire range of research; 2) To enhance quality, safety, and efficiency of CTR for all diseases and condifions in our environment; 3) To develop new innovafions that advance clinical and translational sciences; 4) To facilitate the training and career development of a robust translafional research workforce. To accomplish these goals, we propose an integrafive approach with cross-cutting support for T1-T4 translafional sciences, interoperable biomedical informafics, therapeufics development, child health research, and patient- and population-centered outcomes research. We also propose to build on research core services that have evolved and expanded including: 1) Clinical Trials and Regulatory Support Office (CTRSO); 2) Clinical Invesfigafion Services Cores (CISC); 3) Biostafisfics, Epidemiology & Research Design (BERD); 4) Biomarker and Analyfic Research Core (BARC); 5) Biospecimen Repository (BioR); 6) Community Engagement Consultafion Core (CECC); 7) Research Informafics Core (RIC); and 8) Project Accelerafion Resource (PAR). Our Research Training, Education and Career Development program will create an educational environment with a learner-centered approach; focus on the core competencies developed by the CTSA; provide a menu of options to serve learners at various stages of development across the spectrum of clinical and translafional research; and to implement novel mentoring approaches. RELEVANCE (See instructions): This CTSA applicafion proposes an Institufional Clinical and Translafional Science Award (U54) program that conforms to the mission of the Nafional Center for Advancing Translafional Sciences, as expressed in RFA- TR-12-006.