Training in HIV-related Non-communicable Disease Complications in Malawi

项目摘要 该艾滋病毒研究培训计划的总体目标是提高医学院的能力 (COM)马拉维大学和其他地方机构进行非传染性疾病研究 艾滋病毒/艾滋病并发症。该委员会目前正在进行艾滋病毒相关的研究，但通过战略 培训和能力建设，它将转向一个深思熟虑的，协调的研究和临床服务， 在这一新兴和具有挑战性的领域， 优先事项通过短期、中期和长期学位和非学位培训机会的平衡 在约翰霍普金斯大学（JHU），在国内和地区，这一培训计划将提高技能， 以下是对非传染性疾病（NCD）研究至关重要的重点： HIV相关和治疗相关并发症的科学和流行病学;随机设计 和观察性临床研究;获得新的临床评估和研究 技能，包括应用实验室方法、活组织检查和成像，以实施这些研究; 负责任地开展研究;以及数据分析、翻译和传播信息， 科学界。受训人员将与他们所选专业领域的课程教师联系起来; 因此，项目主任和高级关键合作者组成了一个多学科的项目团队， 来自非洲和美国机构的教师。研究能力的提高将在两个层面上加以衡量： 受训者的水平，包括受训人数、受训者研究的传播情况，以及 将其纳入马拉维COM和其他机构与艾滋病毒有关的非传染性疾病研究和规划;以及 机构一级，其中包括艾滋病毒并发症研究的成功研究奖， 制定机构研究战略，包括具体目标。一个关键的和独特的元素， JHU-COM合作的培训环境是在马拉维的布兰太尔进行了20多年的艾滋病毒研究， 现有的基础设施，以支持当地和全球的艾滋病毒研究工作- 与NCD有关。在培训补助期结束时，JHU-COM培训合作将 加强了马拉维当地人的能力，并培养了一批训练有素的人员， 满足艾滋病毒和治疗相关非传染性疾病患者和人群的新需求 并发症虽然JHU-COM合作已经证明了其成功的能力，独立的 艾滋病毒研究，新的福格蒂艾滋病毒研究培训计划将是一个创新和重要的补充 为艾滋病毒相关并发症的区域培训建立非洲研究环境。

PROJECT SUMMARY The overall objective of this HIV research training program is to increase capacity of the College of Medicine (COM), University of Malawi and other local institutions to conduct research in non-communicable disease complications of HIV/AIDS. The COM currently conducts HIV related studies, but through strategic training and capacity building, it will move toward a deliberate, coordinated research and clinical service agenda in this emerging and challenging area for countries with limited resources and competing priorities. Through a balance of short, medium, and long-term degree and non-degree training opportunities at the Johns Hopkins University (JHU), in-country and regionally, this training program will increase skills in the following concentrations which are essential to research in non-communicable diseases (NCDs): the science and epidemiology of HIV-related and treatment-related complications; the design of randomized and observational clinical research studies; the acquisition of new clinical assessment and investigation skills, including applied laboratory methods, biopsies and imaging, to implement these studies; the responsible conduct of research; and data analysis, translation and dissemination of information to the scientific community. Trainees will be linked to program faculty in their selected area of specialization; as such, the program director and senior key collaborator have formed a multidisciplinary team of program faculty from African and U.S. institutions. Increased research capacity will be measured at two levels: the level of the trainee, which includes numbers of individuals trained, dissemination of trainee research, and integration into HIV-related NCD research and planning at COM and other institutions in Malawi; and the level of the institution, which includes successful research awards for HIV complications research and establishing an institutional research strategy including specific targets. A critical and unique element of the training setting for the JHU-COM collaboration is the 20+ years of research in HIV in Blantyre, Malawi and the existing infrastructure from which to build upon to support local and global research efforts in HIV- related NCDs. At the completion of the training grant period, the JHU-COM training collaboration will have strengthened local human capacity in Malawi and created a critical mass of highly trained individuals to address the emerging needs of patients and populations with HIV- and treatment-related NCD complications. While the JHU-COM collaboration has demonstrated its capacity for successful, independent HIV research, the new Fogarty HIV Research Training Program will be an innovative and important addition to establish an African research setting for regional training in HIV-related complications.