Training in HIV-related Non-communicable Disease Complications in Malawi

描述（由申请人提供）：这一艾滋病毒研究培训方案的总体目标是提高马拉维大学医学院和其他地方机构开展艾滋病毒/艾滋病非传染性疾病并发症研究的能力。该中心目前开展与艾滋病毒相关的研究，但通过战略培训和能力建设，它将朝着在这一资源有限和优先事项相互竞争的新兴和具有挑战性的领域制定经过深思熟虑、协调一致的研究和临床服务议程。通过在国家和区域内平衡约翰霍普金斯大学的短期、中期和长期学位和非学位培训机会，这一培训方案将提高对非传染性疾病研究至关重要的以下专业的技能：艾滋病毒相关并发症和治疗相关并发症的科学和流行病学；随机和观察性临床研究的设计；获得新的临床评估和调查技能，包括应用实验室方法、活检和成像，以实施这些研究；负责任的研究行为；以及数据分析、翻译和向科学界传播信息。学员将与所选专业领域的项目教师联系；因此，项目主任和高级主要合作者组成了一个由来自非洲和美国机构的项目教员组成的多学科团队。增加的研究能力将从两个层面来衡量：培训人员的水平，其中包括接受培训的个人人数、培训人员研究成果的传播、以及将艾滋病毒相关的非传染性疾病研究和规划纳入非洲经委会和马拉维其他机构；机构层面，其中包括对艾滋病毒并发症研究的成功研究奖励，以及制定包括具体目标在内的机构研究战略。JHU-COM合作培训环境的一个关键和独特因素是马拉维布兰太尔20多年的艾滋病毒研究和现有基础设施，可以此为基础，支持当地和全球艾滋病毒相关非传染性疾病的研究工作。在培训赠款期结束时，联合保健中心和联合保健中心的培训协作将加强马拉维当地的人力能力，并培养一批训练有素的人员，以满足患有艾滋病毒和与治疗有关的非传染性疾病并发症的患者和人群的新需求。虽然JHU-COM的合作已经证明了它在成功、独立的艾滋病毒研究方面的能力，但新的福格蒂艾滋病毒研究培训计划将是一个创新和重要的补充，以建立一个非洲研究环境，进行艾滋病毒相关并发症的区域培训。

DESCRIPTION (provided by applicant): The overall objective of this HIV research training program is to increase capacity of the College of Medicine (COM), University of Malawi and other local institutions to conduct research in non-communicable disease complications of HIV/AIDS. The COM currently conducts HIV related studies, but through strategic training and capacity building, it will move toward a deliberate, coordinated research and clinical service agenda in this emerging and challenging area for countries with limited resources and competing priorities. Through a balance of short, medium, and long-term degree and non-degree training opportunities at the Johns Hopkins University (JHU), in-country and regionally, this training program will increase skills in the following concentrations which are essential to research in non-communicable diseases (NCDs): the science and epidemiology of HIV-related and treatment-related complications; the design of randomized and observational clinical research studies; the acquisition of new clinical assessment and investigation skills, including applied laboratory methods, biopsies and imaging, to implement these studies; the responsible conduct of research; and data analysis, translation and dissemination of information to the scientific community. Trainees will be linked to program faculty in their selected area of specialization; as such, the program director and senior key collaborator have formed a multidisciplinary team of program faculty from African and U.S. institutions. Increased research capacity will be measured at two levels: the level of the trainee, which includes numbers of individuals trained, dissemination of trainee research, and integration into HIV-related NCD research and planning at COM and other institutions in Malawi; and the level of the institution, which includes successful research awards for HIV complications research and establishing an institutional research strategy including specific targets. A critical and unique element of the training setting for the JHU-COM collaboration is the 20+ years of research in HIV in Blantyre, Malawi and the existing infrastructure from which to build upon to support local and global research efforts in HIV- related NCDs. At the completion of the training grant period, the JHU-COM training collaboration will have strengthened local human capacity in Malawi and created a critical mass of highly trained individuals to address the emerging needs of patients and populations with HIV- and treatment-related NCD complications. While the JHU-COM collaboration has demonstrated its capacity for successful, independent HIV research, the new Fogarty HIV Research Training Program will be an innovative and important addition to establish an African research setting for regional training in HIV-related complications.