HIV Implementation Science Research Training Program

摘要 加州大学伯克利分校（UCB）/加州大学弗朗西斯科分校（UCSF）/斯坦福大学 大学/津巴布韦大学（UZ）福格蒂艾滋病毒实施科学研究培训计划将 为医生、护士、牙医提供多学科培训，以支持实施科学研究， 津巴布韦大学健康科学学院（UZCHS）的药剂师和科学家， 加强UZCHS进行高质量，创新和当地相关的艾滋病毒/艾滋病研究的能力。 拟议的培训方案建立在与艾滋病毒/艾滋病有关的 研究和培训，将针对UZCHS当前和未来的教师;它将增加和加强 UZCHS多个部门提供的研究培训（例如医学，牙科，医学微生物学， 儿科和儿童健康，社区健康，妇产科），在短期和长期 任期，使其能够填补一些目前空缺的教师职位与个人的国家的- 开展高质量艾滋病毒相关研究所需学科的艺术培训，特别是评估 干预措施的影响或比较各种战略和方法的相对有效性， 扩大预防和治疗活动（如流行病学、生物统计学、信息学、社会学和 行为科学，卫生政策和政策分析，以及经济学），从而提高其能力， 为津巴布韦未来几代调查人员提供硕士和博士水平的培训。学员 由该计划支持的学生将在UZCHS现有的博士学位课程中入学，或者在选定的 在这种情况下，是目前UZCHS教师谁可能会或可能不会已经拥有博士学位，但 谁需要额外的博士水平的研究培训。学员将花费有限的时间段（即 一个季度或一个学期的时间）在美国的一个参与美国机构，在那里他们将采取 高级课程在UZCHS不可用;接受指导他们的论文或（非论文） 在规划阶段进行研究，并协助分析、解释和编写摘要， 在数据分析阶段的手稿;并受益于其他类型的职业发展和教师 辅导活动。他们还将提高他们的课堂教学技能，并获得教学材料 他们回到津巴布韦后可以用来授课。论文（或非论文）研究 学员的项目，将尽可能利用数据和生物标本， 通过目前与艾滋病毒/艾滋病有关的合作研究项目和与艾滋病毒/艾滋病有关的预防工作收集的数据 和治疗方案（例如，通过NIH资助的UZ-UCSF临床试验单位及其 ACTG、HPTN、MTN和IMPAACT项目），并通过总统艾滋病紧急救援计划执行机构正在开展的工作， 这些研究机构或在这些项目的基础上，从现有的研究基础设施中受益。学员将 有资格竞争并获得适度的资金为他们的论文（或非论文）研究项目， 以及那些成功完成博士学位（或其他培训）并留在UZCHS的人 教师将有资格申请并获得适度的资金，以启动培训后的研究计划， UZCHS。将优先重视与艾滋病毒/艾滋病有关的研究、培训和研究， 创新的预防战略;扩大和实施预防和治疗方法;以及 影响评估此外，由于其作为疾病和死亡原因的重要性， 津巴布韦，与结核病（TB）有关的研究和研究培训将得到高度重视，特别是 当直接与正在进行的UZ-UCSF合作研究的发病率，传播模式， 结核病和耐多药结核病（MDRTB）的诊断和治疗。所有学员将接受 在计划、进行和分析人类研究结果时涉及的伦理问题。的 培训计划的结果将是UZCHS多个部门的教师人数增加 开展高质量的艾滋病毒/艾滋病和结核病相关研究，这些研究与当地相关，并有助于 加强预防和治疗方案。

Abstract The proposed University of California, Berkeley (UCB)/University of California, San Francisco (UCSF)/Stanford University/University of Zimbabwe (UZ) Fogarty HIV Implementation Science Research Training Program will provide multi-disciplinary training in support of implementation science research to physicians, nurses, dentists, pharmacists, and scientists at the University of Zimbabwe, College of Health Sciences (UZCHS), in order to strengthen the capacity of UZCHS to conduct high quality, innovative, and locally relevant HIV/AIDS research. The proposed training program, which builds on a > 20 year history of collaboration in HIV/AIDS-related research and training, will target current and future faculty of UZCHS; it will augment and strengthen the research training available in multiple departments of UZCHS (e.g. Medicine, Dentistry, Medical Microbiology, Pediatrics and Child Health, Community Health, and Obstetrics and Gynecology) in both the short and long term, enabling it to fill some of the many currently vacant faculty positions with individuals with the state-of-the- art training in disciplines required to conduct high quality HIV-related research, particularly studies that assess the impact of interventions or that compare the relative effectiveness of various strategies and approaches to scaling up prevention and treatment activities (e.g. Epidemiology, Biostatistics, Informatics, Social and Behavioral Sciences, Health Policy and Policy Analysis, and Economics) and thereby augment its ability to provide masters and doctoral level training to future generations of investigators from Zimbabwe. Trainees supported by this program will either be enrolled in existing doctoral degree programs at UZCHS or, in selected circumstances, be current UZCHS faculty who may or may not already possess a doctoral level degree, but who require additional doctoral level research training. Trainees will spend limited blocks of time (i.e. blocks of a quarter or a semester at a time) in the U.S. at one of the participating U.S. institutions, where they will take advanced courses not available at UZCHS; receive mentoring for their dissertation or (non-dissertation) research at the planning stage and assistance with analysis, interpretation, and preparation of abstracts and manuscripts at the data analysis stage; and benefit from other types of career development and faculty mentoring activities. They will also improve their classroom teaching skills and receive instructional materials they can use to give courses once they return to Zimbabwe. Dissertation (or non-dissertation) research projects of the trainees, will, whenever possible, take advantage of data and biological specimens being collected through current collaborative HIV/AIDS-related research projects and HIV/AIDS-related prevention and treatment programs in Zimbabwe (e.g. through the NIH-funded UZ-UCSF Clinical Trials Unit and its ACTG, HPTN, MTN, and IMPAACT projects) and through work being done by PEPFAR-implementing agencies, or build on these projects, benefiting from the existing research infrastructure. Trainees will be eligible to compete for and receive modest funding for their dissertation (or non-dissertation) research project, and those who successfully complete their doctoral degree (or other training) and remain on the UZCHS faculty will be eligible to apply for and receive modest funding to initiate a post-training research program at UZCHS. Priority will be given to HIV/AIDS-related research training and research that focuses on or relates to innovative prevention strategies; scaling up and implementation of prevention and treatment approaches; and impact assessment. In addition, because of its great importance as a cause of morbidity and mortality in Zimbabwe, research and research training related to tuberculosis (TB) will be given high priority, especially when directly linked to ongoing UZ-UCSF collaborative studies of the incidence, transmission patterns, diagnosis, and treatment of TB and multi-drug resistant TB (MDRTB). All trainees will receive training in the ethical issues involved when planning, conducting, and analyzing the results of human research studies. The result of the training program will be an increase in the number of faculty in multiple departments of UZCHS conducting high quality HIV/AIDS- and TB-related research that is locally relevant and that contributes to enhanced prevention and treatment programs.