HPV and Cancer mHealth Prevention Education for HIV Positive Women Pilot Study

应聘者是一名研究助理教授，接受过健康促进、教育和 行为，以及关于艾滋病毒/艾滋病预防、健康差距和卫生服务的博士后培训 研究。她还拥有数据管理专业知识和临床免疫学经验。候选人有 完成了两项初步研究，考察了HPV感染和宫颈癌预防知识、信念 以及对艾滋病毒携带者(WLH)妇女的行为进行筛查。应聘者正在寻求额外的培训 需要开发和实施有效的癌症健康(包括移动健康)沟通和社区 导航战略，以改进世界卫生组织及时利用癌症筛查、诊断和治疗服务以及 程序。候选人的长期目标是为她的独立候选人获得校外研究资金 未来重点预防和控制人乳头瘤病毒介导性癌症的研究计划 5-10年。晋升副教授(终身教职或研究轨道)是一个中间目标， 候选人正在努力在未来五年内实现。正式的说教训练和 将利用体验式学习机会获得癌症预防和控制研究技能 以下领域：癌症健康(包括mHealth)传播、癌症流行病学、HPV介导型 癌症生物学、社区导航、高级流行病学研究技能(例如，社会流行病学、n- OF-1研究性研究设计，以及多水平建模)。候选人将使用癌症预防和 通过拟议职业获得的控制研究和健康沟通知识和技能 发展奖，进行必要的形成性研究，为干预发展提供信息，她将在 审查世界卫生组织寻求和分享癌症健康信息以及他们的非临床艾滋病毒服务 提供者(例如，艾滋病毒/性传播感染风险降低顾问)。非临床艾滋病毒服务提供者将包括在内，因为， 除了这些人已经在世界妇女联合会中推广安全的性行为之外，他们还 还能够接触到世界卫生组织的边缘群体，如无家可归的人。这包括庇护和 无庇护所无家可归的妇女妇女会。候选人的导师和共同导师具有科学专业知识和 以社区为基础的参与式研究经验，将增加拟议的具体 目标正在顺利完成。候选人将首先研究HPV介导的癌症预防。 知识、信念和行为以及癌症健康传播寻求和分享行为 (包括利用技术查找健康信息)(目标1)。这些形成性的研究数据将被 用于为HPV的开发(目标2)和随后的试点测试和评估(目标3)提供信息- 旨在培训已担任同伴的WLH的介导式癌症预防mHealth教育干预 领导者和非临床艾滋病毒服务提供商使用mHealth工具和社区导航战略 开展人乳头瘤病毒介导性癌症预防教育。作为社区导航员，这些个人将使用 癌症健康(包括移动健康)沟通和社区导航战略，以提高认识 关于HPV介导的癌症风险。这将包括促进降低癌症风险的行为，如SAFE 性行为和及时使用推荐的癌症筛查、诊断和治疗服务以及 程序)。将发送召回和提醒消息进行筛查和后续癌症护理 预约。用户定义的社会支持消息也将发送给可能遇到 获得癌症护理障碍。候选人将把科学研究成果传播给当地、 地区、国家和国际观众通过她将在科学会议和 她将举行年度会议，并出版同行评议的出版物。与候选人最相关的问题 获得研究独立性的长期目标是增加她的同行评议出版物的数量 她目前的出版速度大约是每年三本，到年底每年出版四本或更多本 5年培训期，并在#年底前提交至少一份赠款提案(例如，R01级资助) 为期5年的训练期。拟议的职业发展/培训和研究活动将使 实现她长期职业目标的候选人，即成为一名具有以下专业知识的独立癌症研究人员 使用癌症健康通信、社区导航和移动健康技术来解决健康问题 脆弱的、医疗服务不足的世界卫生组织在癌症护理连续体系中遇到的系统故障。 持续的指导和团队科学研究合作的机会将促进候选人的 成功地成为一名独立的癌症研究人员。世界卫生组织和非临床艾滋病毒服务 提供者将从瑞安·怀特资助的诊所和位于城市和 南卡罗来纳州的农村地理区域，代表了艾滋病毒/艾滋病、癌症和 其他慢性病，给医疗服务不足的少数族裔人口带来不成比例的负担。寻址 沿着癌症护理连续体发生的导致错失机会的卫生系统故障 预防、检测、诊断和治疗HPV介导的癌症将有助于减轻癌症发病率的负担 和死亡率之间的这一高癌症风险，弱势群体的WLH。拟议中的HPV介导性癌症 移动健康预防教育干预将在社区环境中进行，并建立在 候选人与当地艾滋病服务组织之间现有的学术和社区合作伙伴关系。这个 候选人有一个支持性的、资源密集型的科学环境来进行她的癌症研究培训。

The candidate is a research assistant professor with academic training in health promotion, education, and behavior, as well as postdoctoral training in HIV/AIDS prevention, health disparities, and health services research. She also has data management expertise and clinical immunology experience. The candidate has completed two pilot studies that examined HPV infection and cervical cancer prevention knowledge, beliefs and screening behaviors among women living with HIV (WLH). The candidate is seeking additional training needed to develop and implement effective cancer health (including mHealth) communication and community navigation strategies to improve WLH's timely use of cancer screening, diagnostic and treatment services and procedures. The candidate's long-term goal is to obtain extramural research funding for her independent research program focusing on the prevention and control of HPV-mediated cancers among WLH over the next 5-10 years. Promotion to associate professor (tenure- or research-track) is an intermediate goal that the candidate is striving to attain within the next five years. A combination of formal didactic training and experiential learning opportunities will be used to acquire cancer prevention and control research skills in the following areas: cancer health (including mHealth) communication, cancer epidemiology, HPV-mediated cancer biology, community navigation, advanced epidemiological research skills (e.g., social epidemiology, n- of-1 research study designs, and, multilevel modeling). The candidate will use the cancer prevention and control research and health communication knowledge and skills acquired through the proposed career development award to conduct formative research needed to inform intervention development in which she will examine cancer health information seeking and sharing among WLH as well as their non-clinical HIV service providers (e.g., HIV/STI risk reduction counselors). Non-clinical HIV service providers will be included because, in addition to the fact that these individuals are already promoting safe sexual practices among WLH, they are also able to reach marginalized groups of WLH such as those who are homeless. This includes sheltered and unsheltered homeless WLH. The candidate's mentors and co-mentors have scientific expertise and community-based participatory research experience that will increase the likelihood of the proposed specific aims being successfully completed. The candidate will first examine HPV-mediated cancer prevention knowledge, beliefs and behaviors, as well as cancer health communication seeking and sharing behaviors (including the use of technology to find health information) (Aim 1). These formative research data will then be used to inform the development (Aim 2) and subsequent pilot testing and evaluation (Aim 3) of an HPV- mediated cancer prevention mHealth education intervention aimed at training WLH who already serve as peer leaders and non-clinical HIV service providers to use mHealth tools and community navigation strategies to disseminate HPV-mediated cancer prevention education. As community navigators, these individuals will use cancer health (including mHealth) communication and community navigation strategies to increase awareness about HPV-mediated cancer risk. This will include promoting cancer risk reducing behaviors such as safe sexual practices and the timely use of recommended cancer screening, diagnostic, and treatment services and procedures). Recall and reminder messages will be sent for screening and follow-up cancer care appointments. User-defined social support messages will also be sent to WLH who may be encountering access to cancer care barriers. The candidate will disseminate the scientific research findings to local, regional, national, and international audiences via presentations that she will give at scientific conferences and annual meetings as well as peer-reviewed publications that she will produce. Most relevant to the candidate's long-term goal of attaining research independence is increasing her number of peer-reviewed publications from her current publication rate of approximately three per year to four or more produced annually by the end of the 5-year training period and the submission of at least one grant proposal (e.g., R01-level funding) by the end of the 5-year training period. The proposed career development/training and research activities will enable the candidate to realize her long-term career goal of becoming an independent cancer researcher with expertise in using cancer health communication, community navigation, and mHealth technologies to address health system failures encountered by vulnerable, medically-underserved WLH along the cancer care continuum. Continued mentoring and opportunities for team science research collaborations will facilitate the candidate's successful progression to being an independent cancer researcher. WLH and non-clinical HIV service providers will be recruited from Ryan White funded clinics and AIDS-service organizations located in urban and rural geographical areas of South Carolina that represent a microcosm of disparities in HIV/AIDS, cancer, and other chronic illness that disproportionately burden medically underserved minority populations. Addressing health system failures that occur along the cancer care continuum that result in missed opportunities to prevent, detect, diagnose and treat HPV-mediated cancers will help to reduce the burden of cancer incidence and mortality among this high cancer risk, vulnerable group of WLH. The proposed HPV-mediated cancer mHealth prevention education intervention will be conducted in a community-based setting and builds upon an existing academic-community partnership between the candidate and a local AIDS-service organization. The candidate has a supportive, resource-intensive scientific environment for her cancer research training.