Basic Training at the Intersection of Innate and Adaptive Immunity in Disease

疾病中先天免疫和适应性免疫交叉点的基础训练

• 批准号: 8548071
• 负责人: Pamela J Fink
• 金额: $ 16.04万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-08-01 至 2018-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8548071
• 关键词: Disease; Natural Immunity; Training; adaptive immunity

DESCRIPTION (provided by applicant): In this application, we request support for six students each year in our pre-doctoral training program in the Department of Immunology at the University of Washington, with Dr. Pamela Fink as Program Director, and Dr. Michael Bevan as Co-Director. This new application reflects the long history of our department, dating back to its inception in 1989, with founding members derived from backgrounds in biochemistry, molecular biology, infectious disease research, and basic immunology. Our department faculty has grown to include specialists in basic research as well as clinicians who study and treat human infectious diseases, autoimmunity, and immunodeficiencies. Our training program combines didactic coursework with student-led discussion groups and rigorous qualifying and general exams, with the goal of developing the next generation of scientists who think, write, and speak clearly about the key scientific questions and how to solve them. Our students are recruited from our own Immunology graduate program, from the UW Molecular and Cellular Biology graduate program, and from the Medical Scientist Training Program. These students benefit from the rich, diverse, and interactive Immunology community at UW and its affiliated institutions. Our pre-doctoral training program incorporates unique elements that will enrich the graduate student experience for supported trainees. These include opportunities to attend specific national meetings annually, formal evaluation of trainees' scientific presentations and progress by a committee composed of members of our training faculty, and dedicated interactions with selected Immunology seminar speakers. An External Advisory Committee will provide ongoing evaluation of the program. Building on 25 consecutive years of NIH T32 support, this application refocuses our training program to draw on the strengths of our departmental research at the interface of innate and adaptive immunity, with an emphasis on allergy, autoimmunity, and infectious disease.

描述（由申请人提供）：在本申请中，我们要求每年支持6名学生参加华盛顿大学免疫学系的博士前培训计划，Pamela Fink博士担任项目主任，Michael Bevan博士担任联合主任。这个新的应用程序反映了我们部门的悠久历史，可以追溯到1989年成立，创始成员来自生物化学，分子生物学，传染病研究和基础免疫学的背景。我们部门的教师已经发展到包括基础研究专家以及研究和治疗人类传染病，自身免疫和免疫缺陷的临床医生。我们的培训计划将教学课程与学生主导的讨论小组和严格的资格考试和一般考试相结合，旨在培养下一代科学家，他们思考，写作和清晰地谈论关键的科学问题以及如何解决这些问题。我们的学生是从我们自己的免疫学研究生课程，从UW分子和细胞生物学研究生课程，并从医学科学家培训计划招募。这些学生受益于UW及其附属机构丰富，多样和互动的免疫学社区。我们的博士前培训计划结合了独特的元素，将丰富研究生的经验，支持学员。这些包括每年参加特定国家会议的机会，由我们培训教师组成的委员会对学员的科学演示和进展进行正式评估，以及与选定的免疫学研讨会发言人进行专门的互动。一个外部咨询委员会将对该方案进行持续评估。在连续25年的NIH T32支持的基础上，该应用程序重新调整了我们的培训计划，以利用我们在先天免疫和适应性免疫界面上的部门研究优势，重点是过敏，自身免疫和传染病。