Basic Training at the Intersection of Innate and Adaptive Immunity in Disease

描述（由申请人提供）：在此申请中，我们要求每年支持六名学生参加我们在华盛顿大学免疫学系的博士前培训项目，由Pamela Fink博士担任项目主任，Michael Bevan博士担任联合主任。这个新的应用程序反映了我们部门的悠久历史，可以追溯到1989年成立之初，创始成员来自生物化学、分子生物学、传染病研究和基础免疫学的背景。我们系的师资队伍已经发展到包括基础研究专家以及研究和治疗人类传染病、自身免疫和免疫缺陷的临床医生。我们的培训计划将教学课程与学生主导的讨论小组以及严格的资格和一般考试相结合，旨在培养下一代科学家，他们能够对关键科学问题进行清晰的思考，写作和表达，并能够解决这些问题。我们的学生来自我们自己的免疫学研究生项目，来自华盛顿大学分子和细胞生物学研究生项目，以及来自医学科学家培训项目。这些学生受益于华盛顿大学及其附属机构丰富、多样和互动的免疫学社区。我们的博士前培训计划包含独特的元素，将丰富研究生的经验，支持学员。这些包括每年参加特定国家会议的机会，由我们培训教员组成的委员会对受训者的科学报告和进展进行正式评估，以及与选定的免疫学研讨会演讲者进行专门的互动。外部咨询委员会将对该计划进行持续评估。在连续25年的NIH T32支持的基础上，该应用程序重新集中了我们的培训计划，以利用我们部门在先天免疫和适应性免疫界面的研究优势，重点是过敏，自身免疫和传染病。

DESCRIPTION (provided by applicant): In this application, we request support for six students each year in our pre-doctoral training program in the Department of Immunology at the University of Washington, with Dr. Pamela Fink as Program Director, and Dr. Michael Bevan as Co-Director. This new application reflects the long history of our department, dating back to its inception in 1989, with founding members derived from backgrounds in biochemistry, molecular biology, infectious disease research, and basic immunology. Our department faculty has grown to include specialists in basic research as well as clinicians who study and treat human infectious diseases, autoimmunity, and immunodeficiencies. Our training program combines didactic coursework with student-led discussion groups and rigorous qualifying and general exams, with the goal of developing the next generation of scientists who think, write, and speak clearly about the key scientific questions and how to solve them. Our students are recruited from our own Immunology graduate program, from the UW Molecular and Cellular Biology graduate program, and from the Medical Scientist Training Program. These students benefit from the rich, diverse, and interactive Immunology community at UW and its affiliated institutions. Our pre-doctoral training program incorporates unique elements that will enrich the graduate student experience for supported trainees. These include opportunities to attend specific national meetings annually, formal evaluation of trainees' scientific presentations and progress by a committee composed of members of our training faculty, and dedicated interactions with selected Immunology seminar speakers. An External Advisory Committee will provide ongoing evaluation of the program. Building on 25 consecutive years of NIH T32 support, this application refocuses our training program to draw on the strengths of our departmental research at the interface of innate and adaptive immunity, with an emphasis on allergy, autoimmunity, and infectious disease.