Correlates among nocturnal agitation, sleep, and urinary incontinence in dementia

痴呆症夜间躁动、睡眠和尿失禁之间的相关性

• 批准号: 8499431
• 负责人: Elena Perkhounkova
• 金额: $ 18.14万
• 依托单位: UNIVERSITY OF VIRGINIA
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-07-01 至 2015-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8499431
• 关键词: Agitation; Alzheimer' s Disease; Area; Behavior; Caregiver Burden; Caregivers; Caring; Communities; Cost Savings; Data; Data Analyses; Data Collection; Dementia; Development; Distress; Emotional; Environment; Family Caregiver; Frequencies; Healthcare Systems; Home environment; Impaired cognition; Incontinence; Institutionalization; Interruption; Intervention; Interview; Laboratories; Language; Lead; Life; Love; Measures; Methods; Outcome; Participant; Pattern; Persons; Quality of life; Questionnaires; Reporting; Research; Research Personnel; Resources; Savings; Sleep; Sleep disturbances; Specific qualifier value; Structure; Symptoms; System; Taxes; Technology; Testing; Time; United States; Urinary Incontinence; Wireless Technology; Work; base; bedwetting; boys; coping; cost; design; effective intervention; experience; innovation; loved ones; novel; nursing intervention; programs; psychologic; satisfaction; sensor; sleep onset

DESCRIPTION (provided by applicant): Seventy to ninety percent of all persons with Alzheimer's Disease (AD) receive care in their homes. For the millions of family caregivers for persons with AD in the U.S., nighttime agitation, sleep disturbances, and urinary incontinence in their care recipients add additional burden to these already burdened caregivers. These disturbances are often reported by caregivers as being the "tipping point" for seeking institutional care for their loved ones. While each of these disturbances are recognized independently in persons with AD, no research, to date, has studied the interrelationships of these challenging behaviors in community-dwelling persons. Effective interventions can be developed and tested once these relationships are better understood. We believe that a primary reason for limited research in this area is related to the resource-intensiveness of collecting these data using conventional methods (i.e., direct observations). Wireless, body sensor networks hold promise as innovative, reliable, and valid means to collect these data. Three specific aims will guide this study: (1) examine the feasibility and acceptability of the use of boy sensors in community-dwelling persons with AD and in their family caregivers; (2) describe patterns of nocturnal agitation, sleep continuity and duration, and nighttime urinary incontinence in community-dwelling persons with AD; and (3) examine the relationships among nocturnal agitation, sleep continuity and duration, and nighttime urinary incontinence (timing, frequency) in persons with AD. We will use a single-group, descriptive design with AD participants and their caregivers (N = 50). Data collection will take place over 5 weeknights in participants' home environments. To measure the feasibility and acceptability of these body sensor systems, we will query family caregivers using a semi-structured interview and questionnaire regarding their satisfaction and ease of enactment with the study components (use of body sensors; alarming systems). This will allow for collection of data concerning the immediate experience of the caregiver, while providing the study team with valuable information upon which to make any needed adjustments prior to our conducting a larger scale study. Wireless, body sensor systems will be used with persons with AD in their natural home settings to collect objective data on nighttime agitation (restlessness, physical and verbal agitation), sleep (sleep onset latency, frequency of nighttime awakenings, wake after sleep onset, and total sleep time), and urinary incontinence (timing, frequency). Data analysis will examine the relationships in terms of timing and duration between incontinence and agitation and the subsequent effects on sleep. Results from this study will provide us with the necessary data to develop and test interventions to decrease or eliminate these problematic disturbances in persons with AD, and to influence positively the daily lives of family caregivers.

描述（由申请人提供）：百分之七十到九十的阿尔茨海默病 (AD) 患者在家中接受护理。对于美国数百万 AD 患者的家庭护理人员来说，护理对象的夜间烦躁、睡眠障碍和尿失禁给这些本来就不堪重负的护理人员增添了额外的负担。护理人员经常将这些困扰报告为为其亲人寻求机构护理的“临界点”。虽然这些障碍中的每一种都在 AD 患者中被独立识别，但迄今为止，还没有研究研究社区居民中这些挑战性行为的相互关系。一旦更好地理解了这些关系，就可以制定和测试有效的干预措施。我们认为，该领域研究有限的主要原因与使用传统方法（即直接观察）收集这些数据的资源密集程度有关。无线身体传感器网络有望成为收集这些数据的创新、可靠和有效的手段。本研究将遵循三个具体目标：(1) 研究在社区 AD 患者及其家庭护理人员中使用男孩传感器的可行性和可接受性； (2) 描述社区 AD 患者的夜间躁动模式、睡眠连续性和持续时间以及夜间尿失禁； (3) 检查夜间躁动、睡眠连续性和持续时间以及夜间尿失禁（时间、频率）之间的关系 患有 AD 的人。我们将对 AD 参与者及其护理人员使用单组描述性设计 (N = 50)。数据收集将在参与者的家庭环境中进行，为期 5 个工作日的晚上。为了衡量这些身体传感器系统的可行性和可接受性，我们将使用半结构化访谈和问卷调查家庭护理人员对研究组件（身体传感器的使用；报警系统）的满意度和实施难易程度。这将有助于收集有关护理人员即时体验的数据，同时为研究团队提供有价值的信息，以便在我们进行更大规模的研究之前进行任何必要的调整。无线身体传感器系统将在 AD 患者的自然家居环境中使用，以收集有关夜间躁动（不安、身体和言语躁动）、睡眠（入睡潜伏期、夜间觉醒频率、入睡后醒来和总睡眠时间）和尿失禁（时间、频率）的客观数据。数据分析将检查失禁和躁动之间的时间和持续时间之间的关系以及随后对睡眠的影响。这项研究的结果将为我们提供必要的数据，以制定和测试干预措施，以减少或消除 AD 患者的这些问题性干扰，并积极影响家庭护理人员的日常生活。

项目成果

Use of Body Sensors to Examine Nocturnal Agitation, Sleep, and Urinary Incontinence in Individuals With Alzheimer's Disease.

使用身体传感器检查阿尔茨海默病患者的夜间躁动、睡眠和尿失禁情况。

• DOI: 10.3928/00989134-20180626-03
• 发表时间: 2018
• 期刊: Journal of gerontological nursing
• 影响因子: 1.3
• 作者: Rose,KarenM;Lach,John;Perkhounkova,Yelena;Gong,Jiaqi;Dandu,SriramRaju;Dickerson,Robert;Emi,IfatAfrin;Fan,Dawei;Specht,Janet;Stankovic,John
• 通讯作者: Stankovic,John

Correlates among nocturnal agitation, sleep, and urinary incontinence in dementia.

痴呆症患者夜间烦躁、睡眠和尿失禁之间存在相关性。

• DOI: 10.1177/1533317514524814
• 发表时间: 2015
• 期刊: American journal of Alzheimer's disease and other dementias
• 作者: Rose,Karen;Specht,Janet;Forch,Windy
• 通讯作者: Forch,Windy