Personal Patient Profile-Prostate: Testing and Implementation in Health Networks

描述(由申请人提供)：P3P是第一个针对局限性前列腺癌(LPC)男性患者的自动化和量身定制的干预措施，在美国样本中证明了有效性。我们有证据表明，P3P减少了决策冲突；用他们的话说，男性能够“为我选择最好的治疗方法。”然而，与许多决策支持技术和干预措施一样，部署作为癌症临床护理的一个组成部分尚未确定，特别是在作为常规做法的可行性和成本方面。LPC可采用一种或多种方法进行治疗，包括单独观察、手术、冷冻手术、激素治疗、近距离放射治疗或外照射。在北美环境下对这些治疗方法进行的随机研究中，很少有研究结果能够充分比较性功能障碍、膀胱功能障碍和肠道功能障碍的并发症。在未来的许多年里，男性将听取临床医生的建议，但也将被要求就前列腺癌的治疗做出重大选择。这些决定可以戏剧性地改变男人的生活。这项混合有效性-实施研究的目的是在地理、种族和种族多元化的医疗保健环境中部署和评估一种有效的、以患者为中心的治疗决策技术，作为支持患有新诊断的LPC的男性的一种手段。我们将收集与使用P3P计划与标准实践的治疗决策准备相关的资源成本。与P3P实施可行性相关的指标将在三个健康网络环境中的每一个中收集，这三个健康网络环境服务于前列腺癌男性的不同人群。

DESCRIPTION (provided by applicant): The P3P is the first automated and tailored intervention for men with localized prostate cancer (LPC) to demonstrate efficacy in a U.S. sample. We have evidence that the P3P decreases decisional conflict; men are able to, in their words, "choose the best treatment for me." Yet as with many decision support technologies and interventions, deployment as an integral component of cancer clinical care has not been established, notably with regard to feasibility as routine practice and to costs. LPC can be treated with one or more modalities including observation alone, surgery, cryosurgery, hormonal therapy, brachytherapy, or external beam radiation therapy. There are few findings from randomized studies of these treatment modalities in North American settings that adequately compare the complications of sexual, bladder, and bowel dysfunction. For many years to come, men will hear clinician recommendations but also will be asked to make major choices about prostate cancer treatments. These decisions can dramatically change men's lives. The purpose of this hybrid effectiveness-implementation study is to deploy and evaluate an efficacious, patient-centered, treatment decision technology in geographically, ethnically and racially diverse health care settings as a means to support men with newly diagnosed LPC. We will collect resource costs associated with preparation for the treatment decision using the P3P program versus standard practice. Metrics associated with viability of P3P implementation will be collected in each of three health network settings which serve a diverse population of men with prostate cancer.