Personal Patient Profile-Prostate: Testing and Implementation in Health Networks

个人患者档案 - 前列腺：健康网络中的测试和实施

• 批准号: 8906980
• 负责人: DONNA L. BERRY
• 金额: $ 9.01万
• 依托单位: DANA-FARBER CANCER INST
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-20 至 2016-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8906980
• 关键词: Adoption; American; Androgens; Bladder; Brachytherapy; Budgets; Caring; Clinical; Clinical Treatment; Conflict (Psychology); Consult; Cost Savings; Costs and Benefits; Cryosurgery; Decision Making; Diagnosis; Effectiveness; Effectiveness of Interventions; Enrollment; External Beam Radiation Therapy; Functional disorder; Goals; Health; Health Benefit; Healthcare; Hearing; Hybrids; Influentials; Intervention; Intestines; Malignant Neoplasms; Malignant neoplasm of prostate; Measures; Methods; Metric; Modality; Newly Diagnosed; Operative Surgical Procedures; Outcome; Participant; Patient Education; Patients; Perception; Physicians; Population Heterogeneity; Preparation; Process; Prostate; Publishing; Qualitative Methods; Randomized; Readiness; Recommendation; Research; Resources; Sampling; Site; Specialist; Technology; Testing; Time; Visit; Work; adverse outcome; cancer therapy; clinical care; cost; deprivation; efficacy testing; group intervention; hormone therapy; implementation trial; men; multi-site trial; patient oriented; preference; programs; promoter; public health relevance; randomized trial; response; routine care; routine practice; satisfaction; secondary outcome; treatment as usual; trial comparing; usability; willingness to pay

DESCRIPTION (provided by applicant): The P3P is the first automated and tailored intervention for men with localized prostate cancer (LPC) to demonstrate efficacy in a U.S. sample. We have evidence that the P3P decreases decisional conflict; men are able to, in their words, "choose the best treatment for me." Yet as with many decision support technologies and interventions, deployment as an integral component of cancer clinical care has not been established, notably with regard to feasibility as routine practice and to costs. LPC can be treated with one or more modalities including observation alone, surgery, cryosurgery, hormonal therapy, brachytherapy, or external beam radiation therapy. There are few findings from randomized studies of these treatment modalities in North American settings that adequately compare the complications of sexual, bladder, and bowel dysfunction. For many years to come, men will hear clinician recommendations but also will be asked to make major choices about prostate cancer treatments. These decisions can dramatically change men's lives. The purpose of this hybrid effectiveness-implementation study is to deploy and evaluate an efficacious, patient-centered, treatment decision technology in geographically, ethnically and racially diverse health care settings as a means to support men with newly diagnosed LPC. We will collect resource costs associated with preparation for the treatment decision using the P3P program versus standard practice. Metrics associated with viability of P3P implementation will be collected in each of three health network settings which serve a diverse population of men with prostate cancer.

描述（由申请人提供）：P3P是第一个针对局限性前列腺癌（LPC）男性的自动化和定制干预，在美国样本中证明了有效性。我们有证据表明P3P减少了决策冲突；用他们的话说，男性能够“选择最适合自己的治疗方法”。然而，与许多决策支持技术和干预措施一样，部署作为癌症临床护理的一个组成部分尚未建立，特别是在作为常规做法的可行性和成本方面。LPC可以通过一种或多种方式治疗，包括单独观察、手术、冷冻手术、激素治疗、近距离治疗或外部放射治疗。在北美地区对这些治疗方式进行的随机研究中，很少有足够的结果来比较性、膀胱和肠道功能障碍的并发症。在未来的许多年里，男性会听到临床医生的建议，但也会被要求对前列腺癌的治疗做出重大选择。这些决定可以极大地改变男人的生活。这项混合有效性-实施研究的目的是部署和评估一种有效的、以患者为中心的治疗决策技术，在地理、种族和种族不同的卫生保健环境中作为一种支持新诊断的LPC男性的手段。我们将收集与使用P3P程序和标准实践的治疗决策准备相关的资源成本。将在服务于不同前列腺癌男性人群的三个卫生网络环境中收集与P3P实施可行性相关的指标。